R.L. Clarke

ORCID: 0000-0003-1859-2502
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About
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Research Areas
  • Ultrasound and Hyperthermia Applications
  • Ultrasound Imaging and Elastography
  • Medical Imaging Techniques and Applications
  • Engineering Education and Curriculum Development
  • Photoacoustic and Ultrasonic Imaging
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Ear Surgery and Otitis Media
  • Atomic and Subatomic Physics Research
  • Head and Neck Anomalies
  • Quantum Chromodynamics and Particle Interactions
  • Otolaryngology and Infectious Diseases
  • Nuclear Physics and Applications
  • Congenital Diaphragmatic Hernia Studies
  • Electrocatalysts for Energy Conversion
  • Vestibular and auditory disorders
  • High-Energy Particle Collisions Research
  • Neonatal and fetal brain pathology
  • Advanced Radiotherapy Techniques
  • Particle physics theoretical and experimental studies
  • Infectious Encephalopathies and Encephalitis
  • Ultrasound and Cavitation Phenomena
  • Electrokinetic Soil Remediation Techniques
  • Histiocytic Disorders and Treatments
  • Neurological diseases and metabolism
  • Analytical Chemistry and Sensors

The University of Texas Southwestern Medical Center
2017-2024

Southwestern Medical Center
2023

Medical City Children's Hospital
2023

Children's Medical Center
2017

Intellectual Ventures (United States)
2009

Carleton University
1973-2003

Institute of Cancer Research
1991-1997

Royal Marsden NHS Foundation Trust
1991-1995

Royal Marsden Hospital
1991-1995

Chevron (United States)
1988

10.1023/a:1003469427858 article EN Journal of Applied Electrochemistry 1998-01-01

Two related methods are described for the determination of electron density a small selected volume within an irregular non-uniform object. The immediate medical application these is in direct measurement mineral content bone. involve manipulation two beams gamma -rays. Four intensities measured, transmitted and scattered radiation. difference between techniques lies ranges energies -rays that can be used.

10.1088/0031-9155/18/4/005 article EN Physics in Medicine and Biology 1973-07-01

SummaryHigh intensity ultrasound may be focused within tissue to produce 'trackless' lesions, that is, destroy selected volumes without damage structures lying between the source of sound beam (the transducer) and target volume. This physical property provides potential for use in a non-invasive 'surgical' technique destruction tissues at depth human body.In this paper, design equipment carry out such surgery is described, its case study involving cat with metastatic melanoma liver outlined....

10.3109/13645709109152791 article EN Minimally Invasive Therapy 1991-01-01

10.1016/s0301-5629(02)00693-2 article EN Ultrasound in Medicine & Biology 2003-01-01

Abstract Using a focused 1.7 MHz ultrasound field (focal length/transducer diameter ratio of 1.7) and in situ intensities spatially averaged within the half-pressure maximum contour range 100–400 W cm−2, ablative lesions have been prescriptively placed singly arrays, livers bladder walls adult female Large White pigs. Exposures were made through skin with up to 8 cm intervening tissue. Ablative under ultrasonic guidance, specific lesion echoes subsequently observed two cases. Animals...

10.1259/0007-1285-67-795-267 article EN British Journal of Radiology 1994-03-01

Background Myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD) is a relatively new entity in the field of demyelinating disorders. Its first diagnostic criteria have recently been published. Objectives We evaluated positive predictive value (PPV) for MOG-IgG testing and report clinical radiologic features with respect to published criteria. Methods A retrospective study was conducted at three centers Dallas, Texas. Patients on cell-based assays any time were included....

10.1177/20552173241274610 article EN cc-by-nc Multiple Sclerosis Journal - Experimental Translational and Clinical 2024-07-01

Cochlear malformations may be subtle on imaging studies. The purpose of this study was to evaluate the angle and depth lateral second interscalar ridge or notch in ears without sensorineural hearing loss (normal ears) compare them with that have a documented incomplete type II partition malformation.The were measured MR normal by single experienced neuroradiologist. images malformation then randomly mixed for 2 novice evaluators measure both blinded manner. For group, interobserver agreement...

10.3174/ajnr.a5585 article EN cc-by American Journal of Neuroradiology 2018-03-15

High-intensity focused ultrasound surgery (FUS) has been developed for the extracorporeal treatment of various benign and malignant soft tissue tumors. The system at Institute Cancer Research/Royal Marsden (ICR/RM) National Health Service (NHS) Trust incorporates a 150 mm focal length bowl transducer operated 1.7 MHz, is currently undergoing Phase 1 clinical trials prostatic hyperplasia superficial bladder cancer. However, application this limited by its to maximum depth 100 mm, power...

10.1109/58.542047 article EN IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 1996-11-01

Recurrent painful ophthalmoplegic neuropathy is a form of cranial neuralgia and rare source pediatric headache. We present 2 children who presented with headaches accompanied by visual symptoms including eye pain, blurry vision, diplopia. MRI in both patients demonstrated enhancement the cisternal segment oculomotor nerve affected side, correlating observed symptoms.

10.1016/j.radcr.2019.05.029 article EN cc-by-nc-nd Radiology Case Reports 2019-06-12

10.1016/0301-5629(94)00128-z article EN Ultrasound in Medicine & Biology 1995-01-01

Neurotoxicity is a rare side effect of metronidazole therapy. Shown here are findings toxicity in patient, who received chronic as prophylaxis for pseudomembranous colitis following bowel resection an infant. Findings depicted include increased T2 signal the dentate nuclei and brainstem. Discontinuing medication resulted reversal findings.

10.1016/j.radcr.2018.09.026 article EN cc-by-nc-nd Radiology Case Reports 2018-10-22

Task-based functional MRI (tb-fMRI) is now considered the standard, noninvasive technique in establishing language laterality children for surgical planning. The evaluation can be limited due to several factors such as age, barriers, and developmental cognitive delays. Resting-state (rs-fMRI) offers a potential path establish dominance without active task participation. authors sought compare ability of rs-fMRI lateralization pediatric population with conventional tb-fMRI used gold...

10.3171/2023.1.peds22497 article EN Journal of Neurosurgery Pediatrics 2023-03-03

Head and neck cancer comprises approximately 12% of all childhood malignancies.1 Common head tumors include those that can occur in other regions the body, such as neuroblastoma, rhabdomyosarcoma, lymphoma, Ewing sarcoma, osteosarcoma, well arising tissues specific to neck, salivary gland malignancies, nasopharyngeal carcinoma, odontogenic neoplasms.1 The presenting signs symptoms pediatric are variable. However, most come attention due presence a visible or palpable mass, functional deficit...

10.1002/pbc.30151 article EN Pediatric Blood & Cancer 2022-12-22

Menkes disease is a rare X-linked recessive disorder caused by impaired copper absorption and transport. Presented here case of 12-week-old male who presented with hypotonia multiple metaphyseal fractures. Further imaging workup revealed diagnosis disease. While nonaccidental trauma much more common cause bone fractures, encephalopathy, subdural hematomas in infants, syndrome should be considered the setting corroborating signs symptoms, as early treatment can delay progression

10.1016/j.radcr.2019.05.012 article EN cc-by-nc-nd Radiology Case Reports 2019-06-05

A search has been made in bubble-chamber film of 7.9 GeV/c deuteron-deuteron interactions for anomalous behavior the collision fragments. No positive effect is seen distribution secondary mean free paths, although stringent limits are placed on primary production rate.

10.1103/physrevd.27.2773 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields 1983-06-01

<title>Abstract</title> <underline><bold>Background</bold></underline><bold>: </bold>Spinal dysraphic states are one of the major indications for fetal MRI. Although widely established nomenclature has been used to describe these lesions in pediatric literature, application studies is inconsistent. <underline><bold>Objective</bold></underline><bold>: </bold>To spinal on MRI using defined measurements and descriptors. An additional objective perform gestational age analysis open dysraphism's...

10.21203/rs.3.rs-5424313/v1 preprint EN cc-by Research Square (Research Square) 2024-11-29

10.1016/s0301-5629(99)00088-5 article EN Ultrasound in Medicine & Biology 1999-11-01

10.1016/0020-708x(75)90126-x article EN The International Journal of Applied Radiation and Isotopes 1975-01-01
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