A5100779271- Hepatitis C virus research
- Metabolism and Genetic Disorders
- Fish Biology and Ecology Studies
- Folate and B Vitamins Research
- Cancer, Hypoxia, and Metabolism
- Assisted Reproductive Technology and Twin Pregnancy
- Acute Myocardial Infarction Research
- Cancer Risks and Factors
- Lung Cancer Treatments and Mutations
- PARP inhibition in cancer therapy
- Blood Coagulation and Thrombosis Mechanisms
- Gestational Diabetes Research and Management
- Biomarkers in Disease Mechanisms
- Lung Cancer Diagnosis and Treatment
- Genomic variations and chromosomal abnormalities
- TGF-β signaling in diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Multiple and Secondary Primary Cancers
- Cancer Research and Treatments
- Plant Pathogens and Fungal Diseases
- Bone health and treatments
- Cardiac Ischemia and Reperfusion
- Berberine and alkaloids research
- Preterm Birth and Chorioamnionitis
- Fish Ecology and Management Studies
Henry M. Jackson Foundation
2024
Uniformed Services University of the Health Sciences
2024
Shandong University
2006-2020
Shandong Provincial Hospital
2020
Anhui Medical University
2012-2018
Nanjing Medical University
2018
Wenzhou Medical University
2018
First Affiliated Hospital of Wenzhou Medical University
2018
Academy of Military Medical Sciences
2015-2017
307th Hospital of Chinese People’s Liberation Army
2015
Background. Long-term studies of the outcome very prematurely born infants have clearly documented that majority such significant motor, cognitive, and behavioral deficits. However, there is a limited understanding nature cerebral abnormality underlying these adverse neurologic outcomes. Aim. The overall aim this study was to define quantitatively alterations in tissue volumes at term equivalent large longitudinal cohort low birth weight premature comparison term-born by using advanced...
Importance The bioequivalence of denosumab biosimilar has yet to be studied in a 53-week, multicenter, large-scale, and head-to-head trial. A clinically effective may help increase access patients with solid tumor–related bone metastases. Objectives To establish the biosimilarity MW032 metastases based on large-scale study. Design, Setting, Participants In this randomized, double-blind, phase 3 equivalence trial, tumors metastasis were recruited from 46 clinical sites China. Overall, 856...
The role of genetic abnormality δ-sarcoglycan (δ-SG) gene in dilated (DCM) and hypertrophied (HCM) cardiomyopathy patients is still unfolding. In this study we first defined the promoter region then searched for polymorphisms/mutations among promoter, 5'-untranslated region, encoding exons δ-SG 104 Chinese with DCM, 145 HCM, 790 normal controls. Two novel polymorphisms were found, an 11 base-pair (bp) deletion (c.-100~-110; -) a missense polymorphism A848G resulting p.Q283R highly conserved...
Individual response to medications varies significantly among different populations, and great progress in understanding the molecular basis of drug action has been made past 50 years. The field pharmacogenomics seeks elucidate inherited differences disposition effects. While we know that populations ethnic groups are genetically heterogeneous, have not found any information regarding minority groups, such as Tajik group northwest China.We genotyped 85 Very Important Pharmacogene (VIP)...
Background Diabetes has been associated with increased risk of fracture and impaired healing. The aim this study was to examine the influence diabetes on perioperative complications, length stay ambulatory ability recovery in individuals hip fracture, determine whether changes could be made improve treatment outcome. Methods included 707 patients treated at Beijing Jishuitan Hospital between July 2009 December 2010. medical history complications were compared non-diabetic diabetic groups....
The present study aimed to investigate the correlation between cystathionine β-synthase (CBS) T833C polymorphisms and primary hypertension. A case-control was conducted by genotyping representative variation in 545 hypertensive individuals (aged 49.23±7.56 years) 500 normotensive 49.90±10.01 years). genetic of CBS enzyme were detected all subjects amplification refractory mutation system polymerase chain reaction (PCR) analysis. polymorphism successfully genotyped general population with a...
To evaluate the feasibility and reliability of cobas 4800 HPV test for cervical cancer screening cytology referral.cobas hybrid capture 2 (HC-2) were used to detect high risk DNA in 670 specimens liquid-based collected from three hospitals. The agreement between HC-2 tests was assessed. PCR detection (HybriBio) gene sequencing genotyping, HPV16 18 genotyped by HybriBio evaluated. Histological diagnosis considered as a gold standard estimate sensitivity specificity vs. detecting CIN2(+)...
Objective This research was aimed to study the safety and efficacy of higher order multifetal pregnancy reduction (MFPR). Study Design a retrospective patients from an academic maternity center between 2005 2015. We evaluated outcomes 131 consecutive who underwent MFPR (quadruplets greater). performed at 11 18 weeks gestation in all cases. In total, 122 cases multiple were reduced twins. discuss perinatal MFPR, followed by comparative analysis that twins 101 nonreduced twin pregnancies....
The delayed effects of radiation alone and combined with skin injury on the kidney are poorly understood. We aimed to unravel compare inflammatory, oxidative stress, survival signaling pathways in cortex before mice manifested renal dysfunction after these two injuries. Mice were analyzed 30 days post irradiation (9.5 Gy for alone, 9.0 a wound). Radiation did not significantly alter BUN, NGAL, or KIM-1 protein levels, indicating preserved function. However, had increased nuanced effect...
Treatment options for patients with squamous cell carcinoma of the lung (SCC) are limited in chemotherapy. However, not all could benefit form standard platinum regimen. Considering dismal prognosis advanced SCC, a greater focus on selecting sensitive chemotherapy regimens remains upmost importance to improve outcomes this disease. In study, we used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry detect pre-chemotherapy serum peptides accepting paclitaxel...
Pedicularis rex C. B. Clarke ex Maxim., an endemic species with potential horticultural traits from Himalaya, has a unique cup-like petiole structure and highly infraspecific floral variation among members of the lousewort genus (Orobanchaceae). We developed 13 microsatellite markers three microsatellite-enriched libraries (AG, AC, AAG) P. modified biotin–streptavidin capture technique. Polymorphism each locus was assessed in 22 individuals representation five populations . Number alleles...