- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Organ Transplantation Techniques and Outcomes
- Neuroscience and Neural Engineering
- Health Systems, Economic Evaluations, Quality of Life
- Pulmonary Hypertension Research and Treatments
- Retinal Development and Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Pregnancy and Medication Impact
- Neonatal Respiratory Health Research
- Endometrial and Cervical Cancer Treatments
- Neurological disorders and treatments
- Maternal and fetal healthcare
- Glaucoma and retinal disorders
- Telomeres, Telomerase, and Senescence
- Infrared Thermography in Medicine
- Uterine Myomas and Treatments
- Cardiac Imaging and Diagnostics
- Gynecological conditions and treatments
- Acute Myocardial Infarction Research
- Single-cell and spatial transcriptomics
- Maternal and Perinatal Health Interventions
Manipal Hospital
2015-2024
Singapore Eye Research Institute
2024
Duke-NUS Medical School
2022-2024
University of Oxford
2020-2023
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Background: Conception by IVF has been associated with an increased incidence of several obstetrical and perinatal complications. is complications like OHSS (Ovarian Hyper Stimulation Syndrome), multiple pregnancies thromboembolism, ectopic pregnancy, congenital malformations, small for gestational age, low birth weight etc. This study done to evaluate compare the obstetric between assisted reproduction spontaneous conception. The objective present was maternal neonatal outcome IVF/ICSI...
There is a growing need to better characterise senescent cells in the CNS and retina. The recently published SenMayo gene panel was developed identify transcriptomic signatures of senescence across multiple organ systems, but retina not included. While other approaches have identified retina, these largely focused on experimental models young animals. We therefore conducted detailed single-cell RNA-seq analysis cell populations different aged mice compared with five comprehensive human mouse...
Abstract Ca 2+ entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated channels (LTCCs) contributes respectively to pacemaker activity DA release, has long been thought contribute vulnerability degeneration in Parkinson’s disease. LTCC function is greater from substantia nigra pars compacta than ventral tegmental area, but this not explained by channel expression level. We tested the hypothesis that LTCC-control of release governed rather local mechanisms, focussing...
Adenomyosis is an abnormality in the uterine wall of women that adversely affects their normal life style. If not treated properly, it may lead to severe health issues. The symptoms adenomyosis are identified from MRI images. It a gynaecological disease infertility. presence red dots uterus major symptom adenomyosis. difference extent these extracted images shows how significant deviation normality is. Thus, we proposed entroxon-based bio-inspired intelligent water drop back-propagation...
To evaluate the potential for change to costs from a decision adopt novel diagnostic pathway referrals cardiology outpatients with symptoms of chest pain.