A5078033073- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- Oral and gingival health research
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Wound Healing and Treatments
- Eosinophilic Disorders and Syndromes
- Autoimmune Bullous Skin Diseases
- Bone Tumor Diagnosis and Treatments
- Tumors and Oncological Cases
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Biomedical Research and Pathophysiology
- Cancer-related molecular mechanisms research
- Medical Imaging and Pathology Studies
- Dental Trauma and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Drug Transport and Resistance Mechanisms
- Cancer Cells and Metastasis
- Cancer and Skin Lesions
- Oral and Craniofacial Lesions
- Molecular Biology Techniques and Applications
- Ear and Head Tumors
- Sinusitis and nasal conditions
- Clinical Nutrition and Gastroenterology
Boston University
2002-2025
Ball State University
2022
Northern Health and Social Care Trust
2016
Antrim Area Hospital
2002-2013
Peterborough and Stamford Hospitals NHS Foundation Trust
2011
Boston Medical Center
2009
Hull Royal Infirmary
2008
BC Cancer Agency
2007
Vancouver General Hospital
2006-2007
University of British Columbia
2007
Transforming growth factor alpha (TGF-alpha) is a pleuripotential cytokine with diverse biological effects, including the ability to influence proliferation of normal cells or neoplastic epithelial cells. Eosinophils are subset granulocytes that normally enter peripheral tissues, particularly those beneath gastrointestinal, respiratory, and urogenital epithelium, where they reside in close proximity elements. In this study, we demonstrate great majority eosinophils infiltrating interstitial...
Abstract Tumour necrosis factor (TNF) α, interleukin (IL) 1β, IL-6 and IL-8 are thought to play a central role in the pathophysiology of sepsis but their acute pancreatitis is unknown. In present study, monocytes were isolated from peripheral blood 26 patients with moderate or severe without biliary sepsis. Secretion these cytokines vitro was measured at intervals during first week illness. Sixteen developed systemic complications. Peak TNF-α secretion significantly higher who complications...
Journal Article TGF-α and EGF-receptor mRNAs in human oral cancer Get access Randy Todd, Todd Department of Oral Medicine Pathology, Harvard School Dental Medicine188 Longwood Avenue, Boston, MA 02115, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Bruce R. Donoff, Donoff Robert Gertz, Gertz Allen L. C. Chang, Chang Phoebe Chow, Chow Karekine Matossian, Matossian Jim McBride, McBride Tao Chiang, Chiang George T. Gallagher, Gallagher David W. Wong 1 1To...
Carcinoma associated fibroblasts (CAFs) form the main constituents of tumor stroma and play an important role in growth invasion. The presence CAFs is a strong predictor poor prognosis head neck squamous cell carcinoma. Despite significant progress determining progression, mechanisms contributing to their activation remain poorly characterized, part due fibroblast heterogeneity scarcity reliable surface markers. To search for such markers oral carcinoma (OSCC), we applied novel approach that...
In order to evaluate the impact of anatomy on spectral properties oral tissue, we used reflectance and fluorescence spectroscopy characterize nine different anatomic sites. All spectra were collected in vivo from healthy mucosa. We analyzed 710 cavity 79 volunteers. From spectra, extracted parameters related morphological biochemical tissue. The parameter distributions for sites compared, also physical tissue site. k-Means cluster analysis was performed identify or groups that showed similar...
ABSTRACT Expression of kératinocyte transglutaminase, a specific differentiation marker, has been examined by immunogold-silver cytochemistry in human epidermis and oral epithelium, mucosal hyperplasia neoplasia. Two major findings have obtained. First, considerable immunoreactivity was evident not only at the plasma membrane (the site cross-linked envelope formation) but also cytoplasm spinous cells, suggesting cytoplasmic function for this transglutaminase. Staining cell border seen...
Aberrant expression of TGF-a is associated with human malignant oral epithelium. Experiments were initiated to determine the cellular sources transforming growth factor-alpha (TGF-a) in cancer. Ten freshly resected cancers and four specimens normal epithelium studied by situ hybridization immunohistochemistry. Tissues probed 35S-labeled sense antisense riboprobes (i) (hTGF-a), (ii) epidermal factor receptor (EGFR) distribution responsive cells, (iii) histone H3 examine and/or EGFR's possible...
We report on multiwavelength target-of-opportunity observations of the blazar PKS 0735+178, located 2.2$^\circ$ away from best-fit position IceCube neutrino event IceCube-211208A detected December 8, 2021. The source was in a high-flux state optical, ultraviolet, X-ray, and GeV gamma-ray bands around time event, exhibiting daily variability soft X-ray flux. data Swift-XRT NuSTAR characterize transition between low-energy high-energy components broadband spectral energy distribution (SED),...