A5101936261- Bioinformatics and Genomic Networks
- Neuroinflammation and Neurodegeneration Mechanisms
- Epigenetics and DNA Methylation
- Pancreatic function and diabetes
- Bauxite Residue and Utilization
- T-cell and B-cell Immunology
- Plant-derived Lignans Synthesis and Bioactivity
- Immune cells in cancer
- Endoplasmic Reticulum Stress and Disease
- Birth, Development, and Health
- Immune Response and Inflammation
- Genomics, phytochemicals, and oxidative stress
- Prenatal Screening and Diagnostics
- Electrokinetic Soil Remediation Techniques
- Genetic Syndromes and Imprinting
- RNA modifications and cancer
- Reproductive Health and Technologies
- Microbial Metabolic Engineering and Bioproduction
- Biological Activity of Diterpenoids and Biflavonoids
- Liver Disease Diagnosis and Treatment
- Clay minerals and soil interactions
- Childhood Cancer Survivors' Quality of Life
- Neonatal Respiratory Health Research
- Immune Cell Function and Interaction
Tianjin University of Traditional Chinese Medicine
2024
Hunan Agricultural University
2017-2021
Sun Yat-sen University
2015
Lurie Children's Hospital
2012-2013
Memorial Medical Center
2012
Beijing Proteome Research Center
2011
Maternal obesity is associated with a variety of common diseases in the offspring. One possible underlying mechanism could be maternal induced alterations DNA methylation. However, this hypothesis yet to tested. We performed epigenomic mapping cord blood among 308 Black mother‐infant pairs delivered at term Boston Medical Center using Illumina HumanMethylation27 BeadChip. Linear regression and pathway analyses were conducted evaluate associations between methylation levels prepregnancy BMI...
Prenatal development and early childhood are critical periods for establishing the tissue-specific epigenome, may have a profound impact on health disease in later life. However, epigenomic profiles at birth remain largely unexplored. The focus of this report is to examine individual variation longitudinal pattern genome-wide DNA methylation levels from through first two years life 105 Black children (59 males 46 females) enrolled Boston Medical Center. We performed mapping cord blood venous...
Cigarette smoke‐ (CS‐) induced oxidative stress and inflammation in the lung are serious health problems. Primary reprocessed tea products contain multiple antioxidants that have been reported to protect against CS‐induced injury. However, beneficial effects of Eurotium cristatum fermented loose dark (ECT) particle metabolites (ECP) on injury its potential hepatic metabolic detoxification still unclear. Therefore, sixty mice were randomly divided into six equal groups. CS‐exposed prevented...
The family of Toll-like receptors (TLRs) has recently been reported to play a role in ischemic injury, but the time course and cell types post-stroke TLR9 upregulation remain unclear. In this study, we investigated dynamic changes expression neurons glial cells after cerebral ischemia reperfusion mice.Focal was induced by middle artery occlusion for 90 min male C57BL/6 mice. levels tissue surrounding infarct were detected Western Blot at 6 h, 3 d, 7 14 21 28 d reperfusion. observed...
Modifications of red mud for activating available silicon (Si) by phosphates were carried on in this paper. And then the modified materials used to stabilize Cd an ore soil. Results indicated that efficiently increase content Si mud. In stabilization, exchange was decreased 90.97% when using 5% potassium dihydrogen phosphate mud, which better than raw re as decrease 77.08%. rice pot soil, increases residue positively correlated with (P<0.05, R=0.9965). Contents root increased 53.87% while...
Genomic imprinting is an epigenetic phenomenon of the monoallelic expression genes depending on their parental origin.Studies animal models show that superovulation and in vitro manipulation culture gametes preimplantation embryos can lead to aysregulation imprinting.These procedures occur also assisted reproductive technology(ART)and might result same changes imprinting.At present time,ART remains imperfect technology with lower embryo implantation rate,higher clinical abortion rate,and...