A5092649054- Photoreceptor and optogenetics research
- DNA Repair Mechanisms
- Molecular Biology Techniques and Applications
- Bacterial Genetics and Biotechnology
- RNA Research and Splicing
Nantes Université
2023
Unité en Sciences Biologiques et Biotechnologies de Nantes
2023
Centre National de la Recherche Scientifique
2023
ABSTRACT To maintain its genome integrity, the cell uses complementary and orchestrated processes, among which is DNA Damage Response. Pre mRNA maturation an essential step of damage response that provides adapted proteome in order to face genotoxic stress. We describe here a new phosphorylation RAD51 recombinase, on Ser97 residue. This Aurora A mediated modulates vitro activity evaluated by D-loop polymerization assays. Using recombinant proteins, we show RNA binding protein affinity ....