A5070223960- Human Health and Disease
- Healthcare Systems and Public Health
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Trypanosoma species research and implications
- Environmental Science and Water Management
- Cardiovascular Effects of Exercise
- Legal and Regulatory Analysis
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Physical Education and Training Studies
- Education and Social Development in Ukraine
- Lysosomal Storage Disorders Research
- Vascular Anomalies and Treatments
- Economic and Technological Developments in Russia
- Military Technology and Strategies
- Educational Robotics and Engineering
- Cardiac Arrhythmias and Treatments
- Cellular transport and secretion
- Global Health Workforce Issues
- Studies on Chitinases and Chitosanases
- Social and Behavioral Studies
- Sports Science and Education
Federal Almazov North-West Medical Research Centre
2018-2025
Ministry of Health of the Russian Federation
2017-2024
S. M. Kirov Military Medical Academy
2020
Civil Service
2020
Cardiovascular morbidity and mortality are associated with high demographic economic losses. Their decrease is one of the main lines development improvement world health systems. An analysis current situation in Russian Federation (RF) demonstrates that areas concern system for cardiovascular diseases (CVD) patients’ care insufficient untimely identification risk factors, as well their ineffective management due to incomplete implementation existing stratification guidelines decision making....
Objective. To develop the classification of subaortic anatomical variants interventricular septum (IVS) and substantiate its practical significance. Material methods. A retrospective study included 244 patients with obstructive hypertrophic cardiomyopathy (HCM) (men 40.6%, mean age 56.8±11.6 years) who underwent septal myectomy between 2011 2022. The inclusion criterion was dynamic LVOT obstruction systolic pressure gradient >50 mm Hg both at rest during stress tests. Patients valvular,...
The high and growing incidence mortality of patients with heart failure (HF) should receive priority attention when developing an action plan to reduce cardiovascular in the Russian Federation. article provides analysis implemented elements HF care 40 regions (Northwestern, North Caucasian, Volga, Southern Federal districts), some best practices, as well prospects for implementation risk management system.
The increasing prevalence of heart failure (HF) serves as a reverse side the effective treatment for cardiovascular diseases (CVD) and patient survival. Data on epidemiology HF related mortality in Russia are limited. According to EPOCHA trial (hospital phase), Russian Federation is 7%. can significantly contribute mortality. However, its recognition limited by peculiarities coding system Russia. article presents authors' view registration HF-related morbidity cases perspectives using left...
Anderson-Fabry disease (AFD) results from decreased enzyme activity of lyzosmal and intralyzosomal storage its nonhydrolyzed. Cadiovascular complications, mainly in s form HCM contribute substantially for AFD-patient’s mortality. Here we report three new cases obstructive (HOCM) due to unclassical presentation AFD isolated cardiac involvement. In all the diagnosis was made postoperative by routine genetic morphological testing. Together with previously published this illustrates potential...
The burnout syndrome among healthcare professionals is a headline problem in the world, as it leads to poor health of medical workers, affects patient satisfaction with care and system whole. At same time, existing preventive measures can improve well-being staff. Aim. To study prevalence professional practicing cardiologists Russian Federation (RF). Material methods. This cross-sectional was carried out using method online anonymous surveying. inclusion criterion current practical activity...
Objective To evaluate prospects for clinical use of circulating biomarkers characterizing fibrotic changes in the myocardium patients with hypertrophic cardiomyopathy (HCMP) left ventricular (LV) outflow tract obstruction.Materials and Methods This was a prospective study 12-month follow-up period. The included 47 (29 females 18 males) obstructive HCMP who were selected septal reduction. Echocardiography (EchoCG), cardiac magnetic resonance imaging (MRI) measurements serum C-reactive...
Raised life expectancy of patients with cardiovascular diseases (CVD), due to continuous progress in drug treatment options and widespread use innovate technologies, increase the burden CVD on healthcare system. The development human resources by highly qualified specialists is fundamental importance. For rational achieve targets federal project prevention diseases, it necessary not only analyze actual situation medical staffing, but also potential effects staff shortages imbalances...
Aim. To analyze congestive heart failure management in the clinical practice of city emergency hospital order to develop new strategies improving health care program for patients with chronic (CHF). Material and methods. We reviewed 343 cases hospitalization due CHF decompensation. 88% had NY HA Class III – IV on admission . The quality was assessed according criteria approved by Ministry Health Russian Federation Society experts failure. Results. Despite fact that ECG chest X-ray were...
Aim. To analyze 20 electrocardiographic (ECG) signs of left bundle branch block (LBBB) before and after septal myectomy in patients with hypertrophic cardio myopathy (HCM) develop a criterion for proximal LBBB based on the selected signs. Material methods . This retrospective non-randomized study included 50 obstructive HCM who underwent myectomy. There were following inclusion criteria: QRS width <120 ms surgery, transaortic access during myectomy, ≥120 early postoperative period. For...
The predictive value of the risk stratification scales in elderly patients with IPAH might differ from that younger patients. It is unknown whether young and older have same survival dependence on PAH-specific therapy numbers. aim this study was to evaluate prognostic relevance PAH medication numbers comparison A total 119 a prospective single-center registry were divided into group I < 60 years old (n = 89) II ≥ 30). ESC/ERS, REVEAL, REVEAL 2.0 scores assessed at baseline, as well H2FpEF...
в данной статье рассмотрим такое понятие как «Подготовка гимнастов на начальном этапе». Оно имеет большое значение жизни спортсменов. Это направление позволяет понять какой период лучше развиваются такие качества сила, гибкость, быстрота, ловкость, прыгучесть, выносливость у юных гимнастов. Неполно освещены литературе и важные вопросы, содержание методика занятий спортивной гимнастикой с детьми, частности мальчиками 10-12-летнего возраста. Кроме того, до сего времени не определены четкие...
The most common type of cardiomyopathy is hypertrophic (HCM), determined by wall thickening the left ventricle. Most often reason this are mutations in genes encoding sarcomere proteins. However, cases it not possible to establish a clear cause development HCMP due absence causal genes. pronounced myocardial hypertrophy stimulated investigation intracellular processes maintaining homeostasis, particular autophagy. Being one main mechanisms protein quality control muscle cells, at impairment...
Anderson–Fabry disease (AFD) results from decreased enzyme activity of lysosomal enzymes and intralysosomal storage nonhydrolyzed forms. Cardiovascular complications, mainly in the form HCM, contribute substantially to AFD patient mortality. Here, we report three new cases obstructive HCM (HOCM) nonclassical presentations isolated cardiac involvement. In all cases, diagnosis was made postoperatively by routine genetic morphological testing. Together with previously published this illustrates...
Aim . To determine the prevalence and profile of rare variants filamin C gene ( FLNC ) among patients with hypertrophic obstructive cardiomyopathy (HCM) referred for septal myectomy, to provide a clinical description HCM occurring these variants. Material methods Ninety-eight adult who underwent myectomy genetic testing by next-generation sequencing using targeted cardiac panel (39-gene in 58 17-gene 40 patients). In (with minor allele frequency <0,01%), data anamnesis, echocardiography,...
Aim . To develop predictive models for differential diagnostics of hypertrophic phenotype in patients with concomitant diseases, as well to validate through independent assessment. Material and methods The study included an analysis 1169 medical records from the information system severe myocardial hypertrophy a preliminary diagnosis cardiomyopathy (HCM) (I42.1, I42.2). were divided into 3 following groups: probable HCM, moderate (>15 mm) due known disease, that cannot be explained by...
в статье поднимается актуальная проблема, которая связана с повышением стрелковой подготовленности сотрудников органов внутренних дел. Проведен анализ литературных источников о значении огневой подготовки профессиональной деятельности правоохранительных органов. Обозначены профессионально-важные качества, которые влияют на стрелковую подготовленность Предложен инновационный метод способствующий обучению правильному прицеливанию начальном этапе подготовки. Представлены способы прицеливания,...
Despite the fact that principles of diagnosing hypertrophic cardiomyopathy (HCM) are clearly defined in current guidelines, real clinical practice one has to deal with a large number comorbid patients where diagnosis HCM is not so obvious. Objective . To analyze and demographic characteristics referred Almazov National Medical Research Center HCM. Design methods The registry included 1168 who were provisionally or definitively diagnosed period from 2010–2021. Out them, 280 excluded study....
The medical community, researchers and healthcare organizers are constantly challenged by comparing key indexes reflecting the effectiveness of cardiovascular care, primarily for dynamic assessment implementation world's best practices to reduce mortality. analysis health care patients with diseases (CVD) is a complex, multicomponent process, structure tools which differ from country country. Using different data sources, methodological analytical approaches creates certain limitations...
Control of cardiovascular diseases (CVDs), which are the cause premature mortality and high economic costs, is one priorities social policy. Human resources a key link in health system performance. In Russia, there significant geographical heterogeneity distribution medical workers structural disproportions certain specialties. Regional differences availability specialists cardiology have not been studied enough. Aim . To perform comparative benchmark analysis coverage by involved healthcare...
Pulmonary veno-occlusive disease (PVOD) is verified by identifying typical pathological changes in lungs or mutation the EIF2AK4 gene. Clinical suspicion based on combination of specific pulmonary pattern computed tomography scan, hypoxemia with low diffusing lung capacity (DLCO) and inadequate response to therapy arterial hypertension (PAH). The rapid course PVOD high mortality determines importance early diagnosis transplantation refferal. We present an unusual clinical case 40-year-old...