- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiovascular and exercise physiology
- Cardiac Health and Mental Health
- Heart Rate Variability and Autonomic Control
- Viral Infections and Immunology Research
- Pulmonary Hypertension Research and Treatments
- Healthcare Systems and Public Health
- Cardiac Structural Anomalies and Repair
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Eicosanoids and Hypertension Pharmacology
- COVID-19 Clinical Research Studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Issues in Pregnancy
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
Federal Almazov North-West Medical Research Centre
2014-2025
Ministry of Health of the Russian Federation
2014-2020
Orenburg State Medical Academy
2015
Guidelines for the diagnosis and treatment of circulatory diseases in context COVID-19 pandemic
Russian Society of Cardiology (RSC) With the participation: National Myocardial Diseases and Heart Failure, Failure Specialists, Scientific Medical Internal Medicine Endorsed by Research Practical Council Ministry Health Federation (12.09.2024)
Aim To evaluate the efficacy of I NEED HELP scale in determining six-month prognosis for patients on heart transplant waiting list (HTWL) Almazov National Medical Research Center Russian Ministry Health. Material and methods This retrospective study included 42 from HTWL. The patients’ survival more than 6 months was assessed. composite end point (CEP) adverse outcome all-cause death, transplantation (HT) due to increased urgency surgical intervention according UNOS within after inclusion...
Aim: to study the clinical characteristics and genetic spectrum of children with arrhythmogenic cardiomyopathy (ACM) who have undergone heart transplantation (HT) or are currently on waiting list (HTWL) Materials Methods: this included 5 pediatric patients 3 female (60%) diagnosed ACM had either HT were HTWL. The mean age cohort was 16 [7,5; 16]. Comprehensive assessments performed for all participants, including evaluation complaints (palpitations, syncope, symptoms failure (HF)), family...
Russian Society of Cardiology (RSC) With the participation: Eurasian Association Therapists (EUAT), Specialists in Heart Failure (OSSN), Scientific Medical (RNMOT), Pathologists, Radiologists and (RSR) Endorsed by: Research Practical Council Ministry Health Federation
Aim of the RUssian hoSpital Heart Failure Registry (RUS-HFR) was to analyze clinical and epidemiological characteristics, application modern drug non-drug therapy among hospitalized patients with systolic chronic heart failure (CHF) in 3 subjects Russian Federation.We conducted a prospective multicenter observational study cardiological centers (Petersburg, Orenburg, Samara) which we recruited aged 18-75 years left ventricular ejection fraction less or equal 40% without ongoing myocardial...
The high and growing incidence mortality of patients with heart failure (HF) should receive priority attention when developing an action plan to reduce cardiovascular in the Russian Federation. article provides analysis implemented elements HF care 40 regions (Northwestern, North Caucasian, Volga, Southern Federal districts), some best practices, as well prospects for implementation risk management system.
To analyze management and outcomes in patients with CHF managed by specialists heart failure (HF) or general cardiologists/physicians real-life clinical practice.Survival rate, rehospitalization health condition, the administered therapy were evaluated for HF reduced LV ejection fraction at three years of discharge from cardiological hospitals. These had been included a prospective, multicenter, observational study, "The Russian Hospital Registry" (RUS-HFR). The first group consisted who...
The extent of the problem heart failure determines priority intention developing and implementing an optimal model medical care for this group patients. article describes key components (continuity, patient routing, educational activities) provides examples documents, protocols, checklists that can be used in real clinical practice by specialists organizations regions Russian Federation.
The document focuses on key issues of diuretic therapy in CHF from the standpoint current views pathogenesis edema syndrome, its diagnosis, and characteristics using diuretics various clinical situations.
Background and Purpose . In heart failure (HF), metabolic alterations induce skeletal muscle wasting decrease of exercise capacity quality life. The activation regeneration potential is a prospective strategy to reduce wasting; therefore, the aim this project was determine if functional properties mesenchymal progenitor cells (SM-MPC) were affected by HF-induced dysregulations. Methods Gastrocnemius biopsy samples obtained from 3 healthy donors (HD) 12 HF patients purify mRNA for further...
Cardiovascular diseases are widespread and the leading death cause in most countries, despite creation improvement of strategies to reduce cardiovascular risk. A significant role development evolution belongs sympathetic nervous system hyperactivity, therefore methods effecting it relevant for prevention treatment pathology. The article discusses modern approaches interventional conservative regulation autonomic neuromodulation hypertension, heart failure, tachyarrhythmias, as well reflects...
Life-time diagnostics of wild type transthyretin amyloidosis (ATTR(wt)-amyloidosis) is virtually absent, even though ATTR(wt)-amyloidosis an underestimated cause for morbidity and mortality, particularly in the older age group.To study incidence, demographic characteristics, morpho-functional features patients with FC IV CHF LV hypertrophy > 15 mm according to autopsy data.Postmortem reports were retrospectively analyzed (n=141; 19 % males, 81 females) cardiology departments aged ≥69...
Aim. To determine whether the skeletal muscle of patients with chronic heart failure (CHF) retains ability to regenerate and grow; compare effectiveness long aerobic trainings, calculated by an individualized method, conventionally trainings (VO 2 peak values), in relation severity failure, exercise tolerance (ET), ergoreflex activity (ERGO). Material methods . The study included 297 stable III functional class (FC) CHF, receiving optimal therapy. presence was found all at least 6 months...
Aim. To assess the changes of quality life (QoL) in patients after heart transplantation (HTx) and identifying factors associated with its changes. Material methods. We retrospectively assessed register created on basis original database "Mental status transplantation: experience Almazov National Medical Research Center" № 2023622138. There were following inclusion criteria: recipients aged over 18 years preserved cardiac transplant function (Simpson's left ventricular ejection fraction...
In September 2021, an online meeting of the Council Experts was held. The proposed focus discussion publishing results international prospective, randomized, double-blind, placebo-controlled study VICTORIA. objective VICTORIA evaluation efficacy and safety supplementing a standard therapy with vericiguat at target dose 10 mg twice day as compared to placebo for prevention cardiovascular death hospitalization heart failure (HF) in patients clinical manifestations chronic HF left ventricular...
Type 2 diabetes mellitus (T2DM) and chronic heart failure (HF) have close association, several biomarkers been studied to better understand this association improve prediction of HF in T2DM. Furthermore, recent clinical trials, sodium glucose cotransporter inhibitors (SGLT2i), glucose-lowering drugs, improved outcomes. The objective the present study was evaluate between circulating fibrosis incidence with preserved ejection fraction (HFpEF) patients T2DM receiving (SGLT2i). Materials...
Aim. To evaluate the role of erythrocyte anisotropy (RDW) coefficient as a predictor adverse outcome in acutely decompensated chronic heart failure (ADCHF). Material and methods. Totally, 422 patients, age 37-82 y. o. (mean 66,8±2,3 o.) investigated, who had been hospitalized for ADCHF ischemic origin with decreased ejection fraction (EFLV). All participants underwent routine tests, including variation (RDW-CV, RDW-SD), C-reactive peptide (CRP) brain natriuretic (BNP). Instrumental methods...
A method for predicting one-year survival of patients with heart failure and reduced ejection fraction (HFrEF) is required to choose a management tactics determine indications high-tech care at the outpatient stage.To develop proper prediction HFrEF in clinics.This was prospective study 212 functional class II-IV CHF non-valvular origin LV EF (Simpson) ≤35 % aged 18-70, including 176 (83 %) men 36 (17 women who had given an informed consent participate study.hospitalization specialized...