Н. Б. Перепеч

ORCID: 0000-0003-4057-5813
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About
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Research Areas
  • Heart Failure Treatment and Management
  • Healthcare Systems and Public Health
  • Cardiac Health and Mental Health
  • Cardiovascular Function and Risk Factors
  • Blood Pressure and Hypertension Studies
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atrial Fibrillation Management and Outcomes
  • Heart Rate Variability and Autonomic Control
  • Neurological Disorders and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiac Imaging and Diagnostics
  • Clinical practice guidelines implementation
  • Eicosanoids and Hypertension Pharmacology
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Heart rate and cardiovascular health
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intensive Care Unit Cognitive Disorders
  • Cardiovascular and exercise physiology
  • Electrolyte and hormonal disorders
  • Metabolism, Diabetes, and Cancer
  • Hormonal Regulation and Hypertension
  • Health and Medical Research Impacts
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Medication Adherence and Compliance

St Petersburg University
2016-2025

Kharkiv Medical Academy of Postgraduate Education
2015

Russian Society of Cardiology (RSC) With the participation: National Myocardial Diseases and Heart Failure, Failure Specialists, Scientific Medical Internal Medicine Endorsed by Research Practical Council Ministry Health Federation (12.09.2024)

10.15829/1560-4071-2024-6162 article EN cc-by Russian Journal of Cardiology 2024-10-24

Aim. To find out physicians’ knowledge and perceptions about the possibilities of using therapy affecting prognosis in patients with chronic heart failure reduced ejection fraction (CHFrEF). Material methods. Data an anonymous survey 207 physicians (155 cardiologists, 44 internists, 8 other specialists) who past advanced course professional training spring 2023. Questionnaire contained questions reflecting awareness treatment for improving CHFrEF. Results. The quadruple therapy: sacubitril-...

10.20996/1819-6446-2025-3129 article EN cc-by Rational Pharmacotherapy in Cardiology 2025-02-09

Aim. To find out the relationship between awareness level of clinical guidelines on heart failure (HF) with reduced ejection fraction and a number professional characteristics (specialty, work experience, self-assessment level, attitude towards use guidelines, main way document study). improve efficiency development postgraduate education system, factors that influence doctors' should be determined. Material methods. The study included results an anonymous survey 207 doctors (155...

10.15829/1560-4071-2024-5722 article EN cc-by Russian Journal of Cardiology 2024-02-02

In September 2021, an online meeting of the Council Experts was held. The proposed focus discussion publishing results international prospective, randomized, double-blind, placebo-controlled study VICTORIA. objective VICTORIA evaluation efficacy and safety supplementing a standard therapy with vericiguat at target dose 10 mg twice day as compared to placebo for prevention cardiovascular death hospitalization heart failure (HF) in patients clinical manifestations chronic HF left ventricular...

10.18087/cardio.2023.4.n2403 article EN Kardiologiia 2023-05-01

Aim . To study doctors’ knowledge of the clinical guidelines on use oral anticoagulants and identify reasons for poor adherence. Material methods The results 218 questionnaires completed by doctors trained in 2018-2019 were analyzed. questionnaire included 12 items regarding main aspects use. 71.6% respondents cardiologists, 18.8% therapists (including general practitioners) 9.6% representatives other specialties. Results obtained data show that are worse than cardiologists aware indications...

10.20996/1819-6446-2020-10-15 article EN cc-by Rational Pharmacotherapy in Cardiology 2020-11-04

Aim. Examination of knowledge the basic provisions clinical guidelines for management patients with arterial hypertension and finding out readiness doctors practical application updated recommendations Material methods. Anonymous questionnaires 306 served as material study. The questionnaire consisted two parts. introductory part included questions that allow to find specialty, work experience, gender, age, whether respondent has cardiovascular risk factors. main 16 regarding on diagnosis...

10.20996/1819-6446-2019-15-4-502-509 article EN cc-by Rational Pharmacotherapy in Cardiology 2019-09-02

The review is devoted to the clinical efficacy of sodium-glucose cotransporter type 2 (SGLT2) inhibitors. Information on mechanisms drug action given, as well rationale for their use in management patients with diabetes and heart failure (HF) provided. results large-scale randomized trials evaluating SGLT2 inhibitors are discussed. We showed beneficial effect SGLT-2 risk cardiovascular events diabetes. In addition, an evidence ability dapagliflozin empagliflozin improve prognosis HF reduced...

10.15829/1560-4071-2021-4534 article EN cc-by Russian Journal of Cardiology 2021-07-07

Aim . To study how physicians’ commitment to the basic provisions of clinical guidelines (CGs) for diagnosis and treatment chronic heart failure (CHF) has changed over two years document existence. Material methods An anonymous survey was performed 263 physicians (204 cardiologists, 46 internists 13 other specialists) who were trained in advanced training programs 2022. The questionnaire included questions regarding self-assessment respondents’ professional knowledge, their attitude role CGs...

10.18087/cardio.2024.2.n2436 article EN Kardiologiia 2024-02-29

Aim Improvement of quality life is one the most important goals for treatment patients with chronic heart failure (CHF). This study searched ways to increase efficiency CHF based on parameters in during and after exogenous phosphocreatine (EP). Material methods The effect a single course EP functional class (FC) II-IV reduced or mid-range left ventricular ejection fraction was studied as part all-Russia prospective observational BYHEART. presence FC <50 % were confirmed by results 6-min...

10.18087/cardio.2021.7.n1649 article EN cc-by Kardiologiia 2021-07-31

This article provides an overview of data on the role hypertension and dyslipidemia as leading factors determining clinical course athero sclerotic diseases. The need for a multifactorial approach to treatment patients with multiple risk progression such diseases is noted. describes results large-scale international studies confirming benefits combined antihypertensive lipid-lowering therapy. From point view current guidelines available evidence base, potential improving adherence using...

10.15829/1560-4071-2022-5132 article EN cc-by Russian Journal of Cardiology 2022-08-09

The lecture provides a definition of "acute coronary syndrome" and entities that united this term. mechanisms the development clinical manifestation acute syndrome. methods instrumental laboratory diagnostics, rules formulation diagnosis myocardial infarction unstable angina. Provides information on how to assess prognosis risk stratification in patients with

10.26442/cs45215 article EN cc-by-nc Cardiosomatics 2016-03-15

Background. Obesity is an independent risk factor of the cardiovascular complications in patients with arterial hypertension (HTN). It can directly contribute to increase blood pressure (BP). Thus, treatment HTN and obesity becomes a complex clinical problem, which requires new highly effective antihypertensive drugs.
 Aim. To assess effectiveness safety novel angiotensin II receptor blocker azilsartan medoxomil (AZL-M) as monotherapy free combinations diuretics and/or calcium...

10.26442/2075082x.2021.3.201078 article EN cc-by Systemic Hypertension 2021-10-28

The review describes mechanisms of action metabolic myocardial cytoprotectors and recommendations on their use within the pharmacotherapy stable ischemic heart disease. On basis results clinical studies devoted to study trimetazidine effectiveness indications are specified a therapeutic niche this drug in therapy patients with

10.21518/2079-701x-2017-12-36-48 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2017-01-01

Object - to evaluate effect of trimetazidine on functional and mental capacity in patients undergoing II stage cardiac rehabilitation after coronary artery bypass grafting. Material methods. 125 referred for grafting were divided two groups. Patients control group received pharmacotherapy according current guidelines secondary prevention heart disease. Active treatment (n=30) 35 mg bis day additionally. Functional was assessed by six-minute walk test. Mental evaluated psychomotor performance...

10.26442/cs45862 article EN cc-by-nc Cardiosomatics 2017-03-15
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