A5112248440- Musculoskeletal pain and rehabilitation
- Pain Management and Opioid Use
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Opioid Use Disorder Treatment
- Adenosine and Purinergic Signaling
- Cloud Computing and Resource Management
- Endodontics and Root Canal Treatments
- Planetary Science and Exploration
- African cultural and philosophical studies
- Robotics and Sensor-Based Localization
- Space Exploration and Technology
- Spine and Intervertebral Disc Pathology
- Cell Adhesion Molecules Research
- Dental Radiography and Imaging
- Robotics and Automated Systems
- HIV/AIDS Research and Interventions
- Complementary and Alternative Medicine Studies
- Software System Performance and Reliability
- Neuroscience and Neuropharmacology Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Robotic Path Planning Algorithms
- Neurogenesis and neuroplasticity mechanisms
- Pediatric Pain Management Techniques
Massachusetts Institute of Technology
2022-2024
Palo Alto University
2024
Stanford University
1996-2024
Purdue University West Lafayette
2023-2024
Maxim Integrated (United States)
2023
Plano Cancer Institute
2022
GlobalFoundries (United States)
2022
Stanford Medicine
2022
Eastern Virginia Medical School
2005-2021
Hampton VA Medical Center
2021
The interaction between tumor and immune system plays a crucial role in both cancer development treatment response. To facilitate comprehensive investigation of tumor-immune interactions, we have designed user-friendly web portal TISIDB, which integrated multiple types data resources oncoimmunology. First, manually curated 4176 records from 2530 publications, reported 988 genes related to anti-tumor immunity. Second, associated with the resistance or sensitivity cells T cell-mediated killing...
This paper presents the software framework established to facilitate cloud-hosted robot simulation. The addresses challenges associated with conducting a task-oriented and real-time competition, Defense Advanced Research Projects Agency (DARPA) Virtual Robotics Challenge (VRC), designed mimic reality. core of is Gazebo simulator, platform simulate robots, objects, environments, as well enhancements made for VRC maintain high fidelity simulation using degree freedom multisensor robot. other...
Objectives. To describe the characteristics and attitudes toward complementary alternative medicine (CAM) use among primary care patients with chronic pain disorders to determine if CAM is associated better control. Design. Cross-sectional survey. Subjects. Four hundred sixty-three suffering from chronic, nonmalignant receiving at 12 U.S. academic medical centers. Outcome Measure. Self-reported current usage by disorders. Results. The survey had an 81% response rate. Fifty-two percent...
When planning planetary rover missions it is useful to develop intuition and skills driving in, quite literally, alien environments before incurring the cost of reaching said locales. Simulators make possible operate in that have physical characteristics target locations without expense overhead extensive tests. To end, NASA Ames Open Robotics collaborated on a Lunar simulator based open source Gazebo simulation platform leveraging ROS (Robotic Operating System)components. The was integrated...
Compared to the traditional approach of using virtual machines as basis for development and deployment applications running in Cloud-based infrastructures, container technology provides developers with a higher degree portability availability, allowing build deploy their much more efficient flexible manner. A number tools have been proposed orchestrate complex comprising multiple containers requiring continuous monitoring management actions meet application-oriented non-functional...
Volunteer socializers are members of a community who voluntarily help newcomers become familiar with the popular practices and attitudes community. In this paper, we explore social psychological predictors volunteer on reddit, an online news-sharing Through survey over 1000 reddit users, found that identity, prosocial-orientation generalized reciprocity all in Interestingly, user's tenure has quadratic effect socialization behaviors -- new long-time both more likely to than those between. We...
Micropollutants, which occur at low concentration in the environment, are ubiquitous, hazardous, and difficult to remove from water by using current methods. This work introduces hydrogel-based polymeric absorbents containing immobilized micelles for removal of hydrophobic micropollutants water. Acrylated surfactants synthesized self-assemble into with cores. The acrylate groups enable incorporation poly(ethylene glycol) diacrylate (PEGDA) hydrogels free radical polymerization. NMR...
Abstract Autism spectrum disorder (ASD) is a major neurodevelopmental affecting 1 in 36 children the United States. While neurons have been focus to understand ASD, an altered neuro-immune response brain may be closely associated with and interaction could play role disease progression. As resident immune cells of brain, microglia regulate development homeostasis via core functions including phagocytosis synapses. ASD has traditionally considered polygenic disorder, recent large-scale human...
Abstract This article surveyed attending physicians on their work hours, sleep schedule, daytime sleepiness, and the perceived relation of these factors to patient safety, quality care, personal well-being. Physicians answered demographic workload questions attitudinal regarding work-hour limitations; Epworth Sleepiness Scale (ESS) was used measure subjective an 18-item Impact Questionnaire also used. Of 180 participants, 41 (23%) manifested abnormal ESS scores (11 or greater). Private...
Abstract Persistent organic pollutants (POPs), including xenoestrogens and polyfluoroalkyl substances (PFAS), demand urgent global intervention. Fenton oxidation, catalyzed by iron ions, offers a cost‐effective means to degrade POPs. However, numerous challenges like acid dependency, catalyst loss, toxic waste generation hinder practical application. Efforts create long‐lasting heterogeneous catalysts, capable of simultaneously eliminating requirements, sustaining rapid kinetics, retaining...
Micelles immobilized in polymer materials are of emerging interest drug delivery, water treatment and other applications. Immobilization removes the need for membrane-based separation to eliminate micelles from medium, enabling facile extraction delivery diverse industries. This work lays out a coarse-grained molecular dynamics simulations framework rapid identification surfactants use micelle systems. by constraining one end constituent space, mimicking what would occur copolymer system. We...
Neuronal hyperexcitability is a hallmark of epilepsy. It has been recently shown in rodent models seizures that microglia, the brain's resident immune cells, can respond to and modulate neuronal excitability. However, how human microglia interact with neurons regulate mediated by an epilepsy-causing genetic mutation found patients unknown. The SCN2A gene responsible for encoding voltage-gated sodium channel Nav1.2, one leading contributors monogenic epilepsies. Previously, we demonstrated...
Abstract Core body temperature (CBT) is a vital parameter that provides insight into individuals' overall health. However, existing methods to monitor CBT are mainly invasive and limited applications in operating rooms. This work reports soft wearable thermal device with low power operation accurately the core overcome these limitations. The comprises multiple sensors separated insulating materials of different conductivities. design well‐defined gradient characterize heat flux across...
Summary Hydroxyurea (hydroxycarbamide) (HU) for sickle cell anaemia (SCA) is underutilised. Case management an evidence‐based health strategy and in this regard patient navigators (PNs) may provide case SCA. We hypothesised that HU‐eligible patients exposed to PNs would have improved indicators of starting HU adherence. randomised 224 SCA adults into the Start Healing Patients with (SHIP‐HU) Trial. All received care from trained physicians using standardised prescribing protocols....