A5035638254- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Smoking Behavior and Cessation
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
- Cardiac Health and Mental Health
- Health and Lifestyle Studies
- Cardiovascular Function and Risk Factors
- Peripheral Artery Disease Management
- Heart Rate Variability and Autonomic Control
- Alcohol Consumption and Health Effects
- Education, Psychology, and Social Research
- Diet, Metabolism, and Disease
- Cardiovascular and exercise physiology
- Diet and metabolism studies
- Cerebrovascular and Carotid Artery Diseases
- Body Composition Measurement Techniques
- Dementia and Cognitive Impairment Research
- Substance Abuse Treatment and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Thermoregulation and physiological responses
- Health disparities and outcomes
- Dietary Effects on Health
Brno University of Technology
2024-2025
St. Anne's University Hospital Brno
2012-2023
University Hospital Brno
2007-2023
Masaryk University
2014-2023
International Clinical Research Center, St. Anne's University Hospital Brno
2013-2020
Mayo Clinic in Arizona
2013-2017
Mayo Clinic
2013-2015
Paracelsus Medical University
2015
University of Ottawa
2015
Dartmouth–Hitchcock Medical Center
2014
Background: The relationship between central obesity and survival in community-dwelling adults with normal body mass index (BMI) is not well-known. Objective: To examine total cardiovascular mortality risks associated BMI. Design: Stratified multistage probability design. Setting: NHANES III (Third National Health Nutrition Examination Survey). Participants: 15 184 (52.3% women) aged 18 to 90 years. Measurements: Multivariable Cox proportional hazards models were used evaluate the of...
The authors conducted a prospective cohort study to estimate the risk of incident mild cognitive impairment in cognitively normal elderly (aged ≥70 years) individuals with or without neuropsychiatric symptoms at baseline. research was setting population-based Mayo Clinic Study Aging.A classification aging, impairment, and dementia adjudicated by an expert consensus panel based on published criteria. Hazard ratios 95% confidence intervals were computed using Cox proportional hazards model,...
Focused ultrasound has been shown to stimulate excitable cells, but the biophysical mechanisms behind this phenomenon remain poorly understood. To provide additional insight, we devised a behavioral-genetic assay applied well-characterized nervous system of <i>Caenorhabditis elegans</i> nematodes. We found that pulsed elicits robust reversal behavior in wild-type animals pressure-, duration-, and pulse protocol-dependent manner. Responses were preserved mutants unable sense thermal...
Although metabolic syndrome (MetS) could be handled by lifestyle interventions, its relationship with dietary patterns remains unclear in populations from Central Europe. Using data the Kardiovize Brno cohort, present study aims to identify main and evaluate their association MetS risk a random urban sample Brno, Czech Republic. In cross-sectional of 1934 subjects aged 25⁻65 years (44.3% male), were derived food frequency questionnaire (FFQ) administration principal component analysis....
In the European Union, Czech Republic ranks 3rd and 6th for incidence of obesity cardiovascular diseases, respectively. Worldwide, short sleep duration excessive daytime sleepiness (EDS) characterize obese subjects, which in turn exhibit scarce physical activity unhealthy diet. We aimed to understand relationship between irregular patterns, lifestyle factors, such as diet activity, a vulnerable population. 1482 members Kardiovize cohort, random sample urban population, were included...
Background Atherosclerotic cardiovascular disease is highly prevalent in Eastern and Central Europe, where the incidence highest world. The Kardiovize Brno 2030 study was designed as a prospective cohort to investigate complex relationships of outcomes with range biological, psychosocial, environmental, behavioral, economic factors an urban population Czech Republic. Methods We randomly selected 1% sample city residents aged 25–64 years stratified by sex age. assessed traditional novel risk...
Objective: Manual office blood pressure (BP) is still recommended for diagnosing hypertension. However, its predictive value decreased by errors in measurement technique and the white-coat effect. The can be eliminated automated BP (AOBP) taking multiple readings with participant resting quietly alone. Therefore, use of AOBP clinical practice requires a threshold hypertension diagnosis. aim present study was to determine an corresponding 140/90 mmHg manual using data from large random...
Residual stresses are considered as a significant factor influencing the stress-states in arteries. These typically observed through opening angle of radially cut artery segment, often regarded primary descriptor their stress-free state. However, experimental evidence regarding states different layers is scarce. In this study, two protocols, each employing layer-separating sequences, were performed on 17 human common carotid arteries; differences between both protocols found statistically...
In a population-based case-control study, we examined whether moderate and high caloric intakes are differentially associated with the odds of having mild cognitive impairment (MCI). The sample was derived from Mayo Clinic Study Aging in Olmst
The cardio-ankle vascular index (CAVI) is a sensitive non-invasive marker of arterial stiffness and atherosclerosis. aim this work was to compare the CAVI values in patients with dyslipidemia (without diabetes mellitus hypertension) healthy controls.A Total 248 subjects (104 men, 144 women), 55.0 (95% CI 30-70) years age combined hyperlipidemia or primary hypercholesterolemia 537 controls (244 293 women) 40.0 26-62) were included study. Fasting blood samples collected measure serum total...
Objectives: Cardio-ankle vascular index (CAVI), a parameter of arterial stiffness, has been increasingly used for cardiovascular risk estimation. Currently CAVI reference values are derived from the Japanese population. It is not clear whether same can be in white The aim present study was to describe factors influencing and establish values. Methods: A total 2160 individuals randomly selected Brno city population aged 25–65 years were examined. Of these, 1347 patients free disease,...
Background: Intima-media thickness (IMT) has been proposed as a measurement of subclinical atherosclerosis and associated with cardiovascular disease (CVD). Epicardial adipose tissue (EAT) is fat depot between the pericardium myocardium coronary atherosclerosis. The relationship IMT EAT not reported before. We investigated thickness, IMT, CVD risk factors, ideal health (CVH) metrics using subjects from Kardiovize Brno 2030 cohort study, random urban sample population in Central Europe....
Laser Doppler fluxmetry (LDF) is an extraordinary sensitive noninvasive method of examination. It can be used for monitoring changes in the cutaneous peripheral microcirculation(15). uses a monochromatic low-energy laser beam. This beam penetrates tissue and, depending on individual penetration, it reflected, recorded by sensor and subsequently analyzed using Doppler. detects movement cells circulation microcirculation.The light from source delivered via optical fibers to tissue. In collides...
Subjects with normal body mass index but high fat percentage have higher cardiovascular risk than subjects weight and low mass. However, the association of distribution lean carotid–femoral pulse wave velocity (cfPWV) among nonobese apparently healthy individuals has never been assessed. In 136 volunteers (mean age = 45±9 years; 57% women) without manifest disease, cfPWV was measured by applanation tonometry. Fat were dual-energy x-ray absorptiometry. univariate analysis, total (r 0.17; P <...
Many studies have examined the socioeconomic variations in smoking and quitting rates across European region; however, data from Central East countries, where tobacco burden is especially high, are sparse. This study aimed to assess patterns current past prevalence based on cross-sectional a urban population sample.