A5087431344- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Diabetes Treatment and Management
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Infective Endocarditis Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Cardiac Health and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Potassium and Related Disorders
- Cardiac Structural Anomalies and Repair
- Acute Ischemic Stroke Management
- Lipoproteins and Cardiovascular Health
Aalborg University Hospital
2016-2025
University of Copenhagen
2016-2025
Nordsjællands Hospital
2019-2025
Zealand University Hospital
2013-2025
Copenhagen University Hospital
2013-2024
Aalborg University
2015-2024
Gentofte Hospital
2015-2024
Clinical Research Institute
2012-2024
Weatherford College
2024
Heart Foundation
2016-2024
We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than for secondary cardiovascular prevention.In this double-blind trial, we randomly assigned 27,395 participants stable atherosclerotic vascular disease to receive (2.5 mg twice daily) plus (100 once daily), (5 daily). The primary outcome was a composite of death, stroke, myocardial infarction. study stopped superiority the rivaroxaban-plus-aspirin group after mean follow-up 23 months.The occurred...
AimsCarotid–femoral pulse wave velocity (PWV), a direct measure of aortic stiffness, has become increasingly important for total cardiovascular (CV) risk estimation. Its application as routine tool clinical patient evaluation been hampered by the absence reference values. The aim present study is to establish and normal values PWV based on large European population.
Treatment with angiotensin-converting–enzyme (ACE) inhibitors reduces mortality among survivors of acute myocardial infarction, but whether to use ACE in all patients or only selected is uncertain.
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge, evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
The benefit of an implantable cardioverter-defibrillator (ICD) in patients with symptomatic systolic heart failure caused by coronary artery disease has been well documented. However, the evidence for a prophylactic ICDs that is not due to based primarily on subgroup analyses. management improved since landmark ICD trials, and many now receive cardiac resynchronization therapy (CRT).In randomized, controlled trial, 556 (left ventricular ejection fraction, ≤35%) were assigned ICD, 560 usual...
Few population studies addressed the prognostic significance of aortic pulse wave velocity (APWV) above and beyond other cardiovascular risk factors.We studied a sex- age-stratified random sample 1678 Danes aged 40 to 70 years. We used Cox regression investigate value APWV, office pressure (PP), 24-hour ambulatory PP while adjusting for mean arterial (MAP) covariates. Over median follow-up 9.4 years, incidence fatal nonfatal end points, mortality, coronary heart disease amounted 154, 62, 101...
Dronedarone is a new antiarrhythmic drug that being developed for the treatment of patients with atrial fibrillation.
Out-of-hospital cardiac arrest is a major health problem associated with poor outcomes. Early recognition and intervention are critical for patient survival. Bystander cardiopulmonary resuscitation (CPR) one factor among many improved survival.To examine temporal changes in bystander attempts survival during 10-year period which several national initiatives were taken to increase rates of improve advanced care.Patients out-of-hospital was attempted identified between 2001 2010 the nationwide...
Patients with diabetes have an unfavourable prognosis after acute myocardial infarction. In the first DIGAMI study, insulin-based glucose management improved survival. 2, three treatment strategies were compared: group 1, insulin-glucose infusion followed by long-term control; standard and 3, routine metabolic according to local practice.DIGAMI 2 recruited 1253 patients (mean age 68 years; 67% males) type suspected infarction randomly assigned groups 1 (n=474), (n=473), 3 (n=306). The...
Atrial fibrillation occurs frequently in patients with congestive heart failure and commonly results clinical deterioration hospitalization. Sinus rhythm may be maintained antiarrhythmic drugs, but some of these drugs increase the risk death.
Dronedarone is a novel antiarrhythmic drug with electrophysiological properties that are similar to those of amiodarone, but it does not contain iodine and thus cause iodine-related adverse reactions. Therefore, may be value in the treatment patients heart failure.
The long-term effects of sibutramine treatment on the rates cardiovascular events and death among subjects at high risk have not been established.
Both atrial fibrillation and chronic kidney disease increase the risk of stroke systemic thromboembolism. However, these risks, effects antithrombotic treatment, have not been thoroughly investigated in patients with both conditions.
<h3>Background</h3> Patients with atrial fibrillation (AF) often require anticoagulation and platelet inhibition, but data are limited on the bleeding risk of combination therapy. <h3>Methods</h3> We performed a cohort study using nationwide registries to identify all Danish patients surviving first-time hospitalization for AF between January 1, 1997, December 31, 2006, their posthospital therapy warfarin, aspirin, clopidogrel, combinations these drugs. Cox proportional hazards models were...
Background —Studies have suggested that ACE inhibitors an antiarrhythmic effect on ventricular arrhythmias. Whether they atrial fibrillation is unknown. Methods and Results —We investigated the of inhibition with trandolapril incidence in patients reduced left function secondary to acute myocardial infarction. The this study were those who qualified for inclusion into TRAndolapril Cardiac Evaluation (TRACE) study, a randomized double-blind placebo-controlled had sinus rhythm ECG obtained at...
Atrial fibrillation is common in patients with chronic heart failure (CHF). We analysed the risk associated atrial a large cohort of all treated beta-blocker.In COMET, 3029 CHF were randomized to carvedilol or metoprolol tartrate and followed for mean 58 months. prognostic relevance on other outcomes baseline electrocardiogram compared no impact new onset during follow-up. A multivariate analysis was performed using Cox regression model where 10 covariates entered together study treatment...
Patients with infective endocarditis on the left side of heart are typically treated intravenous antibiotic agents for up to 6 weeks. Whether a shift from oral antibiotics once patient is in stable condition would result efficacy and safety similar those continued treatment unknown.
Previous studies reveal major differences in the estimated cardiovascular risk diabetes mellitus, including uncertainty about young patients. Therefore, large of well-defined populations are needed.All residents Denmark > or = 30 years age were followed up for 5 (1997 to 2002) by individual-level linkage nationwide registers. Diabetes patients receiving glucose-lowering medications and nondiabetics with without a prior myocardial infarction compared. At baseline, 71 801 (2.2%) had mellitus...