Edgardo Sandoya
A5064798461- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Health and Lifestyle Studies
- Sodium Intake and Health
- Cardiovascular Syncope and Autonomic Disorders
- Smoking Behavior and Cessation
- Global Public Health Policies and Epidemiology
- Cardiac, Anesthesia and Surgical Outcomes
- Health and Medical Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart rate and cardiovascular health
- Health Systems, Economic Evaluations, Quality of Life
- Hemodynamic Monitoring and Therapy
- Acute Myocardial Infarction Research
- Air Quality and Health Impacts
- Thermoregulation and physiological responses
- Antiplatelet Therapy and Cardiovascular Diseases
- Hormonal Regulation and Hypertension
- Cardiac Health and Mental Health
- Climate Change and Health Impacts
- Antioxidant Activity and Oxidative Stress
- Pharmaceutical Practices and Patient Outcomes
- Nutritional Studies and Diet
- Cardiovascular Disease and Adiposity
Asociación Española de Urología
2005-2025
Universidad de la República de Uruguay
2008-2021
RedCLARA
2021
Centro de Epilepsia y Neurocirugía Funcional
2015-2016
Humana (United States)
2015-2016
Universidad CLAEH
2015
Hospital Perpetuo Socorro
2004-2014
Ruijin Hospital
2010-2014
KU Leuven
2008-2014
Maastricht University
2014
In previous studies, of which several were underpowered, the relation between cardiovascular outcome and blood pressure (BP) variability was inconsistent. We followed health outcomes in 8938 subjects (mean age: 53.0 years; 46.8% women) randomly recruited from 11 populations. At baseline, we assessed BP SD average real 24-hour ambulatory recordings. computed standardized hazard ratios (HRs) while stratifying by cohort adjusting for other risk factors. Over 11.3 years (median), 1242 deaths...
<h3>Importance</h3> Blood pressure (BP) is a known risk factor for overall mortality and cardiovascular (CV)-specific fatal nonfatal outcomes. It uncertain which BP index most strongly associated with these <h3>Objective</h3> To evaluate the association of indexes death composite CV event. <h3>Design, Setting, Participants</h3> Longitudinal population-based cohort study 11 135 adults from Europe, Asia, South America baseline observations collected May 1988 to 2010 (last follow-ups, August...
Background We and other investigators previously reported that isolated nocturnal hypertension on ambulatory measurement (INH) clustered with cardiovascular risk factors was associated intermediate target organ damage. investigated whether INH might also predict hard endpoints. Methods results monitored blood pressure (BP) throughout the day followed health outcomes in 8711 individuals randomly recruited from 10 populations (mean age 54.8 years, 47.0% women). Of these, 577 untreated had...
Previous studies on the prognostic significance of morning blood pressure surge (MS) produced inconsistent results. Using International Database Ambulatory Blood Pressure in Relation to Cardiovascular Outcome, we analyzed 5645 subjects (mean age: 53.0 years; 54.0% women) randomly recruited 8 countries. The sleep-through and preawakening MS were differences with lowest nighttime pressure, respectively. We computed multivariable-adjusted hazard ratios comparing risk ethnic- sex-specific...
Abstract —Previous studies have reported results on 24-hour ambulatory blood pressure (ABP) in Europe and Japan, but no data exists from South America. In this study, we conducted a population survey to identify reference values compare with clinic, home, self-measured values. A random sample of 2650 adults was selected among 190 000 people covered by our prepaid healthcare institution. Clinic (physician nurse) home (nurse) measurements were performed 3 times each, semiautomatic electronic...
Outcome-driven recommendations about time intervals during which ambulatory blood pressure should be measured to diagnose white-coat or masked hypertension are lacking. We cross-classified 8237 untreated participants (mean age, 50.7 years; 48.4% women) enrolled in 12 population studies, using ≥140/≥90, ≥130/≥80, ≥135/≥85, and ≥120/≥70 mm Hg as thresholds for conventional, 24-hour, daytime, nighttime pressure. White-coat was on conventional measurement with normotension, the opposite...
To analyze sex-specific relative and absolute risks associated with blood pressure (BP), we performed conventional 24-hour ambulatory BP measurements in 9357 subjects (mean age, 52.8 years; 47% women) recruited from 11 populations. We computed standardized multivariable-adjusted hazard ratios for associations between outcome systolic BP. During a course of 11.2 years (median), 1245 participants died, 472 cardiovascular causes. The number fatal combined nonfatal events was 1080, 525, 458...
Data on risk associated with 24-hour ambulatory diastolic (DBP24) versus systolic (SBP24) blood pressure are scarce.
Hypertension is the predominant modifiable cardiovascular risk factor. This cohort study assessed association of with percentage time that ambulatory blood pressure (ABP) within target range (PTTR) proposed by 2024 European Society Cardiology (ESC) guidelines for (BP) management. In a person-level meta-analysis 14 230 individuals enrolled in population cohorts, systolic and diastolic ABPs were combined to assess 24-h, daytime, nighttime PTTR thresholds non-elevated ABP set at <115/65,...
The International Database on Ambulatory Blood Pressure Monitoring (1993-1994) lacked a prospective dimension. We are constructing new resource of longitudinal population studies to investigate with great precision what extent the ambulatory blood pressure improves risk stratification.The acronym IDACO refers in relation Cardiovascular Outcome. Eligible based, have fatal as well nonfatal outcomes available for analysis, comply ethical standards, and been previously published peer-reviewed...
The lack of outcome-driven operational thresholds limits the clinical application home blood pressure (BP) measurement. Our objective was to determine an reference frame for BP We measured and clinic in 6470 participants (mean age, 59.3 years; 56.9% women; 22.4% on antihypertensive treatment) recruited Ohasama, Japan (n=2520); Montevideo, Uruguay (n=399); Tsurugaya, (n=811); Didima, Greece (n=665); nationwide Finland (n=2075). In multivariable-adjusted analyses individual subject data, we...
Mean daytime ambulatory blood pressure (BP) values are considered to be lower than conventional BP values, but data on this relation among younger individuals <50 years scarce. Conventional and 24-hour were measured in 9550 not taking antihypertensive treatment from 13 population-based cohorts. We compared individual differences between according 10-year age categories. Age-specific prevalences of white coat masked hypertension calculated. Among aged 18 30, 30 40, 40 50 years, mean was...
The evidence relating mortality and morbidity to heart rate remains inconsistent. We performed 24-hour ambulatory blood pressure monitoring in 6928 subjects (not on β-blockers; mean age: 56.2 years; 46.5% women) enrolled prospective population studies Denmark, Belgium, Japan, Sweden, Uruguay, China. computed standardized hazard ratios for rate, while stratifying cohort, adjusting other cardiovascular risk factors. Over 9.6 years (median), 850, 325, 493 deaths accrued total, cardiovascular,...
Average real variability (ARV) is a recently proposed index for short-term blood pressure (BP) variability. We aimed to determine the minimum number of BP readings required compute ARV without loss prognostic information. was calculated from discovery dataset that included 24-hour ambulatory measurements 1,254 residents (mean age = 56.6 years; 43.5% women) Copenhagen, Denmark. Concordance between full (≥80 readings) and randomly reduced recordings examined, as accuracy. A test 5,353 subjects...
Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited 10 populations. expressed percentage (%) systolic/diastolic readings ≥135/≥85 mm Hg and ≥120/≥70 during day night, respectively, or the area under curve (mm Hg×h) using same ceiling values. During period 10.7 years (median), 1284...
International Database on Ambulatory blood pressure in relation to Cardiovascular Outcomes (IDACO
Participant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) were measured in 17 921 participants (51.3% women; mean age, 54.2 years) from population cohorts. Subsequently, mortality and events recorded. Using multivariable Cox regression, floating absolute risk was computed across 4 age bands (≤60, 61–70,...
Major adverse cardiovascular events are closely associated with 24-hour blood pressure (BP). We determined outcome-driven thresholds for mean arterial (MAP), a BP index estimated by oscillometric devices. assessed the association of major MAP, systolic (SBP), and diastolic (DBP) in population-based cohort (n=11 596). Statistics included multivariable Cox regression generalized R