Kelley R. Branch
A5001064258- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Cardiac Arrest and Resuscitation
- Advanced MRI Techniques and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Medical Imaging Techniques and Applications
- Ultrasound in Clinical Applications
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Trauma and Emergency Care Studies
- Diabetes Management and Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac pacing and defibrillation studies
- Metabolism, Diabetes, and Cancer
- Transplantation: Methods and Outcomes
- Trauma Management and Diagnosis
- Peripheral Artery Disease Management
University of Washington
2016-2025
Hope Heart Institute
2019-2024
University of Washington Medical Center
2002-2023
Seattle University
2005-2021
Massachusetts General Hospital
2019-2020
Harvard University
2020
RELX Group (United States)
2020
London Borough of Camden
2020
Baptist Hospital of Miami
2016
Brooke Army Medical Center
2015
We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than for secondary cardiovascular prevention.In this double-blind trial, we randomly assigned 27,395 participants stable atherosclerotic vascular disease to receive (2.5 mg twice daily) plus (100 once daily), (5 daily). The primary outcome was a composite of death, stroke, myocardial infarction. study stopped superiority the rivaroxaban-plus-aspirin group after mean follow-up 23 months.The occurred...
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus 2019 (COVID-19). Here, we quantify from participants with a diverse range COVID-19 severity, including those requiring hospitalization, outpatients mild disease, individuals resolved infection. We detected plasma RNA 27% hospitalized participants, 13% diagnosed COVID-19. Amongst the COVID-19, report that higher prevalence detectable is associated worse respiratory lower...
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 disease 2019 (COVID-19) patients 190 pre–COVID-19 era controls using VirScan revealed more than 800 epitopes in the SARS-CoV-2 proteome, including 10 likely recognized by neutralizing antibodies. Preexisting antibodies ORF1, whereas only COVID-19 patient primarily spike protein nucleoprotein. A...
Four glucagon-like peptide-1 (GLP-1) receptor agonists that are structurally similar to human GLP-1 have been shown reduce the risk of adverse cardiovascular events among persons with type 2 diabetes. The effect an exendin-based agonist, efpeglenatide, on and renal outcomes in patients diabetes who also at high for is uncertain.
Patients with established coronary artery disease or peripheral often have diabetes mellitus. These patients are at high risk of future vascular events.In a prespecified analysis the COMPASS trial (Cardiovascular Outcomes for People Using Anticoagulation Strategies), we compared effects rivaroxaban (2.5 mg twice daily) plus aspirin (100 versus placebo in mellitus without preventing major events. The primary efficacy end point was composite cardiovascular death, myocardial infarction, stroke....
Patients with chronic coronary artery disease or peripheral and history of heart failure (HF) are at high risk for major adverse cardiovascular events. We explored the effects rivaroxaban without aspirin in these patients.The COMPASS trial (Cardiovascular Outcomes People Using Anticoagulation Strategies) randomized 27 395 participants to 2.5 mg twice daily plus 100 daily, 5 alone, alone. New York Heart Association functional class III IV HF left ventricular ejection fraction (EF) <30% were...
Both sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists reduce cardiovascular events among patients with type 2 diabetes. However, no outcome trial has evaluated the long-term effects of their combined use. The AMPLITUDE-O (Effect Efpeglenatide on Cardiovascular Outcomes) reported that once-weekly injections efpeglenatide (versus placebo) reduced major adverse (MACEs); MACEs, coronary revascularization, or unstable angina hospitalization (expanded...
The aims of the present study were to describe proportion patients eligible for COMPASS trial within Reduction Atherothrombosis Continued Health (REACH) registry, reasons ineligibility, and put in perspective characteristics outcomes trial-eligible from REACH registry compared with those enrolled reference aspirin arm trial. selection exclusion criteria applied either coronary artery disease (CAD) or peripheral (PAD). We used primary composite outcome cardiovascular (CV) death, myocardial...
In dual-modality PET/CT systems, the CT scan provides attenuation map for PET correction. The current clinical practice of obtaining a single helical only snapshot respiratory cycle, whereas occurs over multiple cycles. Misalignment and emission image because motion causes errors in correction factors artifacts attenuation-corrected image. To rectify this problem, we evaluated use cine CT, which acquires low-dose images during cycle. We average intensity-maximum cardiac correction.Cine data...
Abstract Purpose: To compare nongated three‐dimensional (3D) contrast‐enhanced magnetic resonance angiography (CE‐MRA) with 3D‐navigated cardiac‐gated steady‐state free‐precession bright blood (3D‐nav SSFP) and noncontrast 2D techniques for ascending aorta dimension measurements. Materials Methods: Twenty‐five clinical exams were reviewed to evaluate the at 1.5T using: breathhold cine (SSFP), cardiac‐triggered T2 black (T2 BB), axial 3D‐nav SSFP, 3D CE‐MRA. Three radiologists independently...
<h3>Importance</h3> The relative safety and patency of skeletonized vs pedicled internal mammary artery grafts in patients undergoing coronary bypass graft (CABG) surgery are unknown. <h3>Objective</h3> To investigate the association harvesting with clinical outcomes 1 year after CABG surgery. <h3>Design, Setting, Participants</h3> This study was a post hoc analysis multicenter, randomized, double-blind, placebo-controlled Cardiovascular Outcomes for People Using Anticoagulation Strategies...
Background: The COMPASS trial (Cardiovascular Outcomes for People using Anticoagulation Strategies) demonstrated that dual pathway inhibition (DPI) with rivaroxaban 2.5 mg twice daily plus aspirin 100 once versus reduced the primary major adverse cardiovascular event (MACE) outcome of death, myocardial infarction, or stroke, as well as, mortality, in patients chronic coronary syndromes peripheral arterial disease. Whether this remains true a history percutaneous intervention (PCI) is...