Heather Corry
A5008395437- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Cystic Fibrosis Research Advances
- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Long-Term Effects of COVID-19
- Health Systems, Economic Evaluations, Quality of Life
- Liver Disease Diagnosis and Treatment
- COVID-19 Impact on Reproduction
- Pancreatitis Pathology and Treatment
- COVID-19 and Mental Health
- Chronic Disease Management Strategies
Brigham and Women's Hospital
2020-2024
Harvard University
2020-2021
Oxford University Hospitals NHS Trust
2019
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus 2019 (COVID-19). Here, we quantify from participants with a diverse range COVID-19 severity, including those requiring hospitalization, outpatients mild disease, individuals resolved infection. We detected plasma RNA 27% hospitalized participants, 13% diagnosed COVID-19. Amongst the COVID-19, report that higher prevalence detectable is associated worse respiratory lower...
Biological data are lacking with respect to risk of vertical transmission and mechanisms fetoplacental protection in maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.To quantify SARS-CoV-2 viral load neonatal biofluids, transplacental passage anti-SARS-CoV-2 antibody, incidence infection.This cohort study was conducted among pregnant women presenting for care at 3 tertiary centers Boston, Massachusetts. Women reverse transcription-polymerase chain reaction...
Coronavirus disease 2019 (COVID-19) is associated with adverse outcomes, including need for invasive mechanical ventilation and death in people risk factors. Liver enzyme elevation commonly seen this group, but its clinical significance remains elusive. In study, we calculated the Fibrosis-4 (FIB-4) score a cohort of hospitalized patients COVID-19 assessed association severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA, inflammatory cytokine levels, outcome. A total 202...
Abstract The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus 2019 (COVID-19). We quantified from participants with a diverse range COVID-19 severity, including those requiring hospitalization, outpatients mild disease, individuals resolved infection. plasma RNA was detected 27% hospitalized 13% diagnosed COVID-19. Amongst the COVID-19, higher prevalence detectable associated worse respiratory lower absolute lymphocyte...
Patients with coronavirus disease 2019 (COVID-19) have a high prevalence of detectable troponin and myocardial injury. In addition, subset patients COVID-19 has severe acute respiratory syndrome 2 (SARS-CoV-2) viral loads. The objective this study was to understand the relationship among SARS-CoV-2 viremia, troponin, injury in hospitalized COVID-19.SARS-CoV-2 plasma load measured samples drawn from for at academic medical centers. Baseline characteristics clinically obtained high-sensitivity...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week symptoms, whereas viremia peaked within 1 symptom-onset, suggesting early systemic seeding SARS-CoV-2. Remdesivir treatment was associated with faster decay.
ABSTRACT The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus 2019 (COVID-19). We quantified from participants with a diverse range COVID-19 severity, including those requiring hospitalization, outpatients mild disease, individuals resolved infection. plasma RNA was detected 27% hospitalized 13% diagnosed COVID-19. Amongst the COVID-19, higher prevalence detectable associated worse respiratory lower absolute lymphocyte...
Opioid use may impact the HIV-1 reservoir and its reversal from latency. We studied forty-seven virally suppressed people with HIV (PWH) observed that lower concentration of latency agents (LRA), used in combination small molecules did not reverse latency, synergistically increased magnitude re-activation ex vivo, regardless opioid use. This LRA boosting, which combined a Smac mimetic or low-dose protein kinase C agonist histone deacetylase inhibitors, generated significantly more unspliced...
The opioid epidemic may impact the HIV-1 reservoir and its reversal from latency in virally suppressed people with HIV (PWH). We studied forty-seven PWH observed that lowering concentration of agents (LRA), used combination small molecules do not reverse latency, synergistically increases magnitude re-activation