A5067126788- Synthesis and biological activity
- Cancer therapeutics and mechanisms
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- Computational Drug Discovery Methods
- Rice Cultivation and Yield Improvement
- Synthesis and Characterization of Heterocyclic Compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Multicomponent Synthesis of Heterocycles
- Histone Deacetylase Inhibitors Research
- Protein Degradation and Inhibitors
- Antibiotics Pharmacokinetics and Efficacy
- Quinazolinone synthesis and applications
- Irrigation Practices and Water Management
- Inflammatory mediators and NSAID effects
- Plant Stress Responses and Tolerance
- Cholinesterase and Neurodegenerative Diseases
- Synthesis of heterocyclic compounds
- Agricultural Science and Fertilization
- Drug Solubulity and Delivery Systems
- Soil Carbon and Nitrogen Dynamics
- Analytical Chemistry and Chromatography
- Plant responses to water stress
- Cancer Treatment and Pharmacology
- Nitrogen and Sulfur Effects on Brassica
Delhi Pharmaceutical Science and Research University
2020-2025
Indo Soviet Friendship College of Pharmacy
2024
Central Soil Salinity Research Institute
1996-2022
Kurukshetra University
2012-2021
Indian Council of Agricultural Research
2020
Guru Ghasidas Vishwavidyalaya
2013
Maharshi Dayanand University
2013
Manav Bharti University
2013
Cancer, a diverse class of illnesses that have serious impact on the human population, is severe, complicated challenge in health care delivery and public policy. A healthy lifestyle may help us avoid several types cancer. In 2020, there were 10.3 million cancer deaths 19.3 new cases worldwide. lot anticancer medications been discovered due to extensive screening synthetic compounds natural chemicals over last 50 years. The search for chemotherapeutic agents are more effective, selective,...
Abstract A study was conducted to design productive, profitable, irrigation water¸ nitrogen and energy use efficient intensive cereal systems (rice-wheat; RW maize-wheat; MW) in North-West India. Bundling of conservation agriculture (CA) with sub-surface drip termed as CA + were compared alone conventional tillage based flood irrigated rotation (farmer’s practice; ScI). In contrast till which consumed 1889 mm ha −1 water (2-yr mean), system saved 58.4 95.5% MW rotations, respectively....
Docking studies are proved to be an essential tool that facilitates the structural diversity of natural products harnessed in organized manner. In this study, pyridoacridines containing anticancer pigments were subjected docking using Glide (Schrodinger). Investigations carried out find potential molecular targets for these selected pigments. The was on different cancer macromolecules involved cell cycle pathways, is, CDK-2, CDK-6, Bcl-2, VEGFR-2, IGF-1R kinase, and G-Quadruplexes. CDK-6...
Quinazolinone scaffold has been considered as a magic moiety possessing myriad spectrum of medicinal activities. Diversity biological response profile attracted considerable interest several researchers across the globe to explore this skeleton for its assorted therapeutic significance. Various novel classes structurally different quinazolinones have designed and synthesized depicting potential interventions such antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant,...
Histone deacetylase inhibitors (HDACi) have been actively explored as anti-cancer agents due to their ability prevent deacetylation of histones, resulting in uncoiling chromatin and stimulation a range genes associated the regulation cell survival, proliferation, differentiation apoptosis. During past several years, many HDACi entered pre-clinical or clinical research with satisfying results. Out these, more than 8 novel hydroxamic acid based i.e., belinostat, abexinostat, SB939,...