A5059714843- Glaucoma and retinal disorders
- Surface Treatment and Residual Stress
- Plant Genetic and Mutation Studies
- Chromosomal and Genetic Variations
- Prenatal Screening and Diagnostics
- Plant Disease Resistance and Genetics
- Corneal Surgery and Treatments
- Powdery Mildew Fungal Diseases
- Gestational Trophoblastic Disease Studies
- Plant Pathogens and Resistance
- Endometriosis Research and Treatment
- Fatigue and fracture mechanics
- Trauma and Emergency Care Studies
- Cerebral Venous Sinus Thrombosis
- Ultrasound and Hyperthermia Applications
- Pelvic and Acetabular Injuries
- Yeasts and Rust Fungi Studies
- School Health and Nursing Education
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Gear and Bearing Dynamics Analysis
- Sexual Differentiation and Disorders
- Ectopic Pregnancy Diagnosis and Management
- Plant Toxicity and Pharmacological Properties
- Injury Epidemiology and Prevention
All India Institute of Medical Sciences
2012-2025
Dr. Rajendra Prasad Government Medical College
2023
The University of Queensland
2021
Indian Agricultural Research Institute
1996-2002
National Research Centre on Plant Biotechnology
1996
University of Jammu
1984
To analyze exome sequence data from Indian cases with primary congenital glaucoma (PCG) for pathogenic variants. In this cross-sectional observational study, ten consecutive, unrelated patients a clinical diagnosis of PCG residing in India were enrolled. Medical history, family and complete ocular examination carried out all patients. Whole-exome sequencing was performed analyzed Pathogenic or likely variants CYP1B1 FOXC1 identified 3 cases, c.1169 G>A; p.Arg390His (homozygous 2 cases)...
Congenital adrenal hyperplasia (CAH) is one of the inborn errors metabolic disorder inherited in an autosomal recessive manner caused by defects steroid 21 hydroxylase CYP21A2 gene. We analyzed genotype 62 patients with classic CAH.To find out underlying mutations gene.Cohort CAH patients.Sixty-two were recruited from endocrine clinic at AIIMS. Electrochemiluminiscence method was used for estimating levels cortisol. Radioimmunoassay kit-based 17 OHP levels. Polymerase chain reaction...
Abstract Somatic hybrids of Sinapis alba + Brassica juncea (Sal Sal AABB) were synthesized by protoplast electrofusion. They true genomic allopolyploids since they possessed 60 chromosomes, i.e. the sum S. (2 n = 24) and B. 36) chromosomes. Chromosome pairing was predominantly bivalent with occasional occurrence multivalents in pollen mother cells at diakinesis metaphase I. Hybrids completely pollen‐sterile, but produced seeds on back‐crossing campestris. A total 37 BC 1 plants raised from...
PACG is one of the leading causes blindness where lens thickness a major risk factor for narrow-angle individuals. To our knowledge, no literature has been reported on candidate gene as quantitative trait (QT). Here, we performed genome-wide association analysis in individuals.We conducted study (GWAS) narrow angle individuals to investigate comprehensive genetic insights thickness. In QT-GWAS, identified 145 suggestive significant loci discovery cohort. Subsequently, observed 13 SNPs that...
Abstract Problem HLA‐G polymorphisms have a functional impact on its expression and may cause breakdown of maternal tolerance towards the semi‐allogenic fetus, resulting in recurrent spontaneous abortions (RSA). This study reports association regulatory region with idiopathic RSA. Methods Seventy‐five couples ≥2 were recruited comparison to 75 healthy who had normal pregnancies. About 5 mL blood samples collected from all participants, DNA was extracted. Screening 5′‐upstream (5′‐URR) done...
Objectives: This study, using a questionnaire and pulmonary function tests (PFTs), was aimed at assessing the prevalence of respiratory diseases impact environmental factors on these diseases. Materials Methods: 201 schoolteachers, residing in an urban area moderate altitude (2200m), were administered standardized subjected to PFTs. The data obtained statistically analyzed. Results: 28.35% subjects had one or more chronic symptoms. Shortness breath present 16.41%; wheeze 14.43%; cough 8.46%;...
Purpose To report the occurrence of unilateral, neonatal-onset congenital glaucoma in a child with Rubinstein–Taybi Syndrome (RTS).
Background: Liver diseases during pregnancy present unique challenges, with diverse clinical manifestations, necessitating specialized care to reduce maternal and fetal morbidity mortality. This study investigated outcomes in pregnant women presenting jaundice, shedding light on this complex interplay between liver function pregnancy.Materials Methods: A prospective observational was conducted at Dr. Rajendra Prasad Government Medical College, spanning one year 2020. The included abnormal...
PURPOSE: To describe three anterior segment dysgenesis disorders with infantile corneal opacities, namely, congenital hereditary endothelial dystrophy (CHED), primary glaucoma (PCG), and Peters anomaly (PA) in terms of clinical characteristics, histopathology, genetic association, diagnostic imaging profiles using modalities such as ultrasound biomicroscopy (UBM) microscope-integrated intraoperative optical coherence tomography (i-OCT). MATERIALS AND METHODS: Seventy-four eyes 22 CHED, 28...
Giant placental chorioangioma is a rare non trophoblastic tumour originating from primitive angioblastic tissues. It may lead to various maternal and fetal complications like massive antepartum hemorrhage, sudden intrauterine demise non-immune hydrops. Mirror syndrome which association of edema hydrops fetalis an infrequently reported with chorioangioma. We report case 35-year-old pregnant woman, G4P1L1LA2 who was referred at 31wks 5 days POG cardiomegaly in fetus. On examination patient had...