A5101716775- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Sleep and related disorders
- Heart Rate Variability and Autonomic Control
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Diet and metabolism studies
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Catalytic Processes in Materials Science
- Sleep and Wakefulness Research
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Non-Invasive Vital Sign Monitoring
- Gas Sensing Nanomaterials and Sensors
- Nasolacrimal Duct Obstruction Treatments
- ZnO doping and properties
- Electronic and Structural Properties of Oxides
- Cardiac electrophysiology and arrhythmias
- Catalysis and Oxidation Reactions
Kyoto University
1993-2025
University of Wisconsin–Madison
2024
Iwate Medical University
2023
Taipei Veterans General Hospital
2021
Saiseikai Matsuyama Hospital
2020
Uwajima City Hospital
2017
Osaka Red Cross Hospital
2017
Tohoku University
1990-2015
Katsushika Medical Center
2011
Shizuoka University
2009
We examined whether an additive treatment with angiotensin receptor blocker, olmesartan, reduces the mortality and morbidity in hypertensive patients chronic heart failure (CHF) treated angiotensin-converting enzyme (ACE) inhibitors, β-blockers, or both. In this prospective, randomized, open-label, blinded endpoint study, a total of 1147 symptomatic CHF (mean age 66 years, 75% male) were randomized to addition olmesartan (n = 578) baseline therapy vs. control 569). The primary was composite...
Rationale: The effects of telemedicine on adherence in patients with obstructive sleep apnea long-term continuous positive airway pressure (CPAP) use have never been investigated.Objectives: To examine a intervention CPAP users.Methods: In prospective, randomized, multicenter noninferiority trial conducted 17 centers across Japan, who had used for >3 months and were receiving face-to-face follow-up by physicians every 1 or 2 randomized coordinating center blind manner to the following three...
It is well known that the prevalence of sleep disordered breathing (SDB) increased in patients with obesity or metabolic comorbidities. However, way which SDB increases relation to comorbidities according severity remains unclear. This cross-sectional study evaluated 7713 community participants using nocturnal oximetry ≥2 nights. was assessed by 3% oxygen desaturation index corrected for duration obtained wrist actigraphy (acti-ODI3%). defined acti-ODI3%. Obesity as body mass ≥25 kg·m −2 ....
While nocturnal hypoxia caused by sleep-disordered breathing (SDB) can result in polycythemia, the association between erythrocyte values and SDB may vary sex menopausal status. This study aimed to evaluate correlation of variables with a large cohort categorized status from general population. Sleep duration were assessed community residents using wearable actigraph pulse oximeter. The Actigraph-adjusted 3% oxygen saturation index (Acti-3% ODI) was calculated correcting time measured...
Abstract Objective Sleep restfulness is closely associated with mortality. Thus, it an important sleep-related symptom in the general population. However, rarely evaluated patients obstructive sleep apnea (OSA) syndrome. The present study examined importance of OSA receiving continuous positive airway pressure (CPAP) therapy. Materials and Methods We administered questionnaires, which included items such as subjective duration restfulness, to 775 CPAP was rated using a 5-point Likert-type...
OBJECTIVE Left ventricular remodeling occurs immediately after MI, involving structural changes in noninfarcted segment. However, the residual left pump function NIDDM patients acute MI has not been clarified. The purpose of this study was to evaluate difference process between and nondiabetic patients. RESEARCH DESIGN AND METHODS regional EF images obtained by radionuclide angiography were investigated 20 29 3rd wk MI. RESULTS Regional area P/V had a significant hyperbolic relation with EDV...
An extension of the Consolidated Standards Reporting Trials (CONSORT) statement provides a checklist items to improve reporting quality abstracts randomized controlled trials (RCTs). However, authors in some fields have poorly adhered this guideline. We did an extensive literature survey examine trial major critical care journals before and after announcement CONSORT guideline for abstracts.We reviewed RCTs published four with publication dates ranging from 2006 2007 (pre-CONSORT) 2011 2012...
Purpose: To determine the quality of life (QOL) and vision (QOV) patients who developed did not develop dry eye disease (DED) after nasolacrimal duct obstruction (NLDO) treatment. Methods: This was a retrospective nonrandomized observational study 91 diagnosed with unilateral NLDO. The subjects underwent lacrimal stent insertion, removed 10-12 weeks. QOL QOV were examined preoperatively at 6 months removed. postoperative outcomes assessed subjectively Glasgow Benefit Inventory (GBI)...
Abstract Background To broaden the utility of heart rate variability (HRV) in clinical medicine and mass screening, results based on shorter electrocardiogram (ECG) recordings require validation with those standard 5‐minute recordings. We investigated association between HRV variables obtained from ECGs than 5 minutes. Methods Twenty‐two participants aged 20–69 years underwent resting ECG supine position natural breathing. Spectral analysis using MemCalc method was performed to calculate...
Background: Although the safety and effectiveness of stem cell therapies are yet to be proven, recent studies show that such being advertised with some questionable marketing techniques effect positive portrayal on webpages private-practice clinics sell their worldwide. In context, those communicate directly consumers (patients family members) via clinics’ websites. Meanwhile, Health Science Council at Ministry Health, Labour, Welfare (MHLW) in Japan has pointed out noncompliance local...
Since subjective sleep duration (SSD) is considered to be longer than objective (OSD), results of SSD minus OSD (SSD-OSD) might always thought positive. Some recent reports showed different results, but exact have not been obtained. The difference between and may change according OSD. We investigated this its association with sleep-disordered breathing (SDB) or nonrestorative sleep.This cross-sectional study evaluated 6,908 community residents in Nagahama, Japan. was determined by...
The purpose of these experiments was to determine whether overdrive suppression conduction (OSC), i.e., transient worsening or development atrioventricular block after cessation rapid pacing, could be produced in the canine His-Purkinje system damaged by ligation anterior septal coronary artery and investigate responsible mechanism. We found that OSC occurred vivo ventricular His bundle pacing but not atrial it vitro from left branch proximal bundle. related duration cycle length pacing....
小学2年生の通常学級における給食準備場面、給食片付け場面、掃除場面で行動上の問題を示していた児童に対して個別的支援を行い、その後、学級全体に対する支援を実施した。支援実施後は、すべての場面において対象児童の行動は改善されたが、学級全体に対する支援を実施した期間のほうが、個別的支援を実施した期間よりも高く安定した効果が得られた。また、学級全体に対する支援を実施した期間においては、対象児童の行動だけではなく、学級の他の児童の行動にも改善がみられた。以上のような結果から、通常学級における行動支援を検討する際には、児童に対する個別的支援よりも学級全体に対する支援を優先して検討することの必要性が示唆された。社会的妥当性に関しては、手続きの効果の面では担任教師から高い評価を得られたが、手続きの実施に関して、部分的に高い負担感が示された。
The extended cytoplasmic processes from megakaryocytes (MK) are believed to be structural intermediates between MK and platelets. We could observe differentiation of purified rat CFU-MK toward mature form processes. Recombinant interleukin-3 (IL-3), human erythropoietin (Epo), interleukin-6 (IL-6) each was able stimulate process formation although they varied somewhat in their potential. Electron microscopic observations showed that these were very similar those so far reported. combination...