A5032562960- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Medical Imaging Techniques and Applications
- Breast Implant and Reconstruction
- Colorectal and Anal Carcinomas
- Head and Neck Cancer Studies
- Radiation Detection and Scintillator Technologies
- Prostate Cancer Treatment and Research
- Endometrial and Cervical Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Brain Metastases and Treatment
- Prostate Cancer Diagnosis and Treatment
- Digital Radiography and Breast Imaging
- Glioma Diagnosis and Treatment
- Boron Compounds in Chemistry
- Metastasis and carcinoma case studies
- Radioactive contamination and transfer
- Global Cancer Incidence and Screening
- Airway Management and Intubation Techniques
- Nuclear reactor physics and engineering
- Medical Imaging and Analysis
Ospedale Policlinico San Martino
1997-2025
National Cancer Research Institute
2008-2015
University of Genoa
2009-2015
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2013
Medica (Italy)
2013
Alleanza Contro il Cancro
2010-2012
Istituto Nazionale di Fisica Nucleare, Sezione di Genova
1998
To evaluate whether androgen deprivation impacts late rectal toxicity in patients with localised prostate carcinoma treated three-dimensional conformal radiotherapy. One hundred and eighty-two consecutive 3DCRT between 1995 1999 at our Institution least 12 months follow-up were analysed. radiotherapy consisted 70–76 Gy delivered a 3-field arrangement to the prostate±seminal vesicles. As part of treatment, 117 (64%) received neo-adjuvant concomitant while 88 (48.4%) continued on end as well....
Since its introduction the PinPoint (PTW-Freiburg) micro-ionization chamber has been proposed for relative dosimetry (output factors, depth dose curves, and beam profiles) as well determination of absolute small high-energy photon beams. This paper investigates dosimetric performance a new design (type 31014) ion with central aluminum electrode. The study included characterization inherent radiation-induced leakage, collection efficiency polarity effect, response chamber, measurement...
Abstract Purpose This work introduces BreastWatch, a Varian Eclipse script tool designed to help medical physicists, dosimetrists, and radiation oncologists easily inspect improve External Beam Breast Treatment (EBBT) plans using automatic evaluation of protocol dose‐constraints enhanced by Community‐Based approach. Methods BreastWatch examines EBBT Plans Plan Sums, automatically testing the plan's DVH against built‐in international (NRG RTOG1005, ICR Fast‐Forward, FAST, EUROPA 1.2)...
After radical prostatectomy (RP) radiotherapy (RT) plays a role, both as adjuvant or salvage treatment. If negative features are present such extracapsular extension, seminal vesicle invasion, lymph and positive surgical margins, RT after RP reduces the risk of recurrence, although it is associated with an increased acute late toxicities. An intensified delivered in shortened time could improve clinical outcome be safely combined hormonal therapy (HT). The aim this study was to determine...
Abstract Background Radiation therapy after lumpectomy is a standard part of breast conserving for invasive carcinoma. The most frequently used schedule worldwide 60 Gy in 30 fractions 6 weeks, time commitment that sporadically may dissuade some otherwise eligible women from undertaking treatment. purpose and primary endpoint this perspective study to evaluate feasibility short-term late toxicity hypofractionated whole irradiation schedule. Methods Between February October 2008 we treated 65...
Ruthenium ophthalmic applicators are energetic beta ray sources, supplied in several shapes and dimensions, used intraocular tumor therapy. Because of their small the determination dosimetric characteristics represents a technical challenge. We developed semi‐automatic method to define surface dose, dose distribution, percentage depth such using radiochromic media. These detectors consist thin (7 μm) radiation sensitive layer on polyester base (100 μm total thickness) changing color as...
To evaluate local recurrence (LR) in women with early breast cancer (BC) who underwent intraoperative radiation therapy electrons particles (IORT-E) or adjuvant hypofractionated external radiotherapy (HYPOFX).We retrospectively analyzed 470 patients BC treated at our center from September 2009 to December 2012. 235 were breast-conserving surgery and immediate IORT-E (21 Gy/1 fraction) while wide excision followed by whole-breast irradiation. Radiotherapy modality was chosen according an...
AIM:To investigate the toxicity and response of intensity-modulated radiotherapy schedule intensified with a simultaneous integrated boost in anal canal cancer. METHODS: From March 2009 to 2014, we retrospectively analyzed 41 consecutive patients treated (IMRT) concurrent chemotherapy for squamous cell carcinoma at our center.Radiotherapy was delivered via (SIB) technique by helical tomotherapy, doses were adapted two clinical target volumes according tumor-nodemetastasis (TNM) stage: 50.6...
To evaluate the feasibility and report preliminary results for stereotactic radiosurgery (SRS) treatments of single or multiple brain metastases delivered with helical tomotherapy (HT) by means InterFix™ Radiosurgery kit. Between September 2010 August 2012, thirty patients underwent SRS treatment 46 a median prescription dose 20 Gy (range 15-21 Gy). Clinical response was assessed 2-3 month intervals magnetic resonance imaging (MRI). Dose distribution indexes were computed compared published...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Giannelli F, Chiola I, Belgioia L, et al. Complete response in a patient with gynecological hidradenocarcinoma treated exclusive external beam radiotherapy and brachytherapy: case report. Journal of Contemporary Brachytherapy. 2017;9(6):572-578. doi:10.5114/jcb.2017.71554. APA Giannelli, F., Chiola, I., Belgioia, L., Garelli, S., Pastorino, A., & Marcenaro, M. (2017). Brachytherapy, 9(6), 572-578....
Several studies have shown that the majority of in-breast recurrences following lumpectomy are at or near original tumor site while ipsilateral breast further a field occur rarely. This suggests radiation dose could be delivered exclusively to bed, allowing larger fractions used without increasing toxicity and shortening total treatment time. We investigated use MammoSite irradiation system with view analyzing complications, cosmesis patient comfort. Between 2004 2007 intracavity...
To evaluate once-weekly hypofractionated radiotherapy in elderly patients affected by early breast cancer, reporting acute and late toxicity profiles, treatment feasibility.Fifty were treated with a regimen: 28.5±2.5 Gy five fractions at one fraction weekly. Simultaneous integrated boost (SIB) to the tumor bed high-risk cases.patients over 70 years old, pT1-2, N0-1a. Acute toxicities assessed based on Radiation Therapy Oncology Group.The median follow-up was 20 months patient age 79 years....
Background The aim of this study was to evaluate retrospectively the planned dose distribution and acute toxicity adjuvant hypofractionated whole breast radiotherapy (RT) delivered in prone vs. supine position. Methods Twenty-four patients were enrolled; 12 underwent RT with a setup setup. We included according volume (≥500 mL), disease stage (≤pT2/pN1), clinical/biological features. Patients received regimen 35 Gy 10 fractions for 2.5 weeks, concomitant boost 3/4 1 fraction/week. Target...
To report the 5-year minimum follow-up in low-risk breast cancer patients treated with a double-lumen balloon-brachytherapy device one mono-institutional Italian experience. Local control data and cosmetic outcomes were collected analyzed.Between October 2004 December 2007, we 30 early stage who underwent conservative surgery followed by adjuvant accelerated partial irradiation system. Eligibility criteria for protocol based on indications of American Brachytherapy Society Breast Surgeons....
To report the 5-year minimum follow-up in low-risk breast cancer patients treated with a double-lumen balloon-brachytherapy device one mono-institutional Italian experience. Local control data and cosmetic outcomes were collected analyzed.Between October 2004 December 2007, we 30 early stage who underwent conservative surgery followed by adjuvant accelerated partial irradiation system. Eligibility criteria for protocol based on indications of American Brachytherapy Society Breast Surgeons....