A5001296588- Mycotoxins in Agriculture and Food
- Complementary and Alternative Medicine Studies
- Ethnobotanical and Medicinal Plants Studies
- melanin and skin pigmentation
- Dermatologic Treatments and Research
- Skin Protection and Aging
- Plant Pathogens and Fungal Diseases
- Moringa oleifera research and applications
- Natural Antidiabetic Agents Studies
- Indoor Air Quality and Microbial Exposure
- Essential Oils and Antimicrobial Activity
- Phytochemistry and biological activity of medicinal plants
- Bioactive Compounds and Antitumor Agents
- Global Maternal and Child Health
- Herbal Medicine Research Studies
- Natural product bioactivities and synthesis
- Plant-Microbe Interactions and Immunity
- HIV/AIDS Impact and Responses
- Food Quality and Safety Studies
- Natural Compound Pharmacology Studies
- Ethics in Clinical Research
- Phytochemicals and Medicinal Plants
- Fungal and yeast genetics research
- Probiotics and Fermented Foods
- Wheat and Barley Genetics and Pathology
University of KwaZulu-Natal
2011-2025
Africa Health Research Institute
2021-2025
Durban University of Technology
1970-2024
Howard College
2021
University of South Africa
2013
Mangosuthu University of Technology
2005
University of Michigan
2005
University of Strathclyde
1996
Computer-aided digital chest radiograph interpretation (CAD) can facilitate high-throughput screening for tuberculosis (TB), but its use in population-based active case-finding programs has been limited. In an HIV-endemic area rural South Africa, we used a CAD algorithm (CAD4TBv5) to interpret x-rays (CXR) as part of mobile health effort. Participants with TB symptoms or CAD4TBv5 score above the triaging threshold were referred microbiological sputum assessment. During initial pilot phase,...
An experiment with a full factorial design was used to study the effects of and interactions among temperature, water activity (a(infw)), incubation period, substrate on coproduction aflatoxins (AF) cyclopiazonic acid (CPA) by an isolate Aspergillus flavus. Analysis variance showed that there complex interaction all these factors this influenced relative concentrations mycotoxins produced. The optimum temperatures for production AF CPA were 30(deg)C 25(deg)C, respectively. Both maximally...
No abstract available
Traditional health practitioners (THPs) play a significant role in South African healthcare. However, the Basic Conditions of Employment Act (BCEA) does not consider sick notes issued by THPs to be valid. This creates dilemma for employees, whose right consult practitioner their choice is protected Constitution. We assessed current legislation and highlight challenges that employees face selecting healthcare system choice. The services represent an untapped capacity can complement strengthen...
Aims: Aflatoxin B1 (AFB1) is a mycotoxin which known to frequently contaminate poorly stored food products destined for human consumption. This study was carried out investigate the potential activity of lactic acid fermentation in reducing AFB1 level fermented maize meal products. Methods and Results: Maize spiked with 60 μg g−1 fermented, or without starter culture, 4 days at 25°C. Unbound solution pH media were monitored daily. A significant decrease (P < 0·05) unbound observed (75%...
Background People living with HIV (PLHIV) in resource-limited settings are vulnerable to malnutrition. Nutritional interventions aimed at improving food insecurity and malnutrition, together antiretroviral therapy (ART), could improve treatment outcomes. In Nigeria, there is a high awareness of the nutraceutical benefits Moringa oleifera . Thus, this study evaluate effects leaf supplementation on CD4 counts, viral load anthropometric HIV-positive adults ART. Methods This was double-blind,...
The treatment and management of diabetes mellitus (DM) with conventional therapies, such as insulin injections oral hypoglycemic agents, present significant challenges due to their side effects burdensome administration. Therapies often manage symptoms rather than addressing regulation, akin medications like thiazolidinediones glinides, which resemble many medicinal plants. Medicinal plants offer potential alternative treatments bioactive compounds targeting causes. We aimed explore the...
We surveyed households in rural and urban areas of KwaZulu Natal, South Africa, to assess the exposure inhabitants fumonisin B(1) (FB(1)), a mycotoxin produced by Fusarium verticillioides. In southern African regions maize, used as staple food population, is prone F. verticillioides infection. Furthermore, high levels FB(1) maize have been associated with esophageal cancer Africa. assessed population at three levels, namely, analyzing stored plate-ready food, feces. The positions...
Traditional complementary and alternative medicine (TCAM) has been reported to be commonly used among individuals with HIV AIDS disease. However a lack of communication between health care workers (HCWs) patients as well HCWs TCAM practitioners identified one the challenges that may adversely affect treatment patients. With improved sustained HCWs, would able make informed decisions regards best practices based on knowledge what is safe, effective not. In order establish baseline...
Background Sutherlandia frutescens (L.) R. Br. is widely used as an over the counter complementary medicine and in traditional medications by HIV seropositive adults living South Africa; however plant's safety has not been objectively studied. An adaptive two-stage randomized double-blind placebo controlled study was to evaluate of consuming dried S. with CD4 T-lymphocyte count >350 cells/μL. Methods In Stage 1 56 participants were 400, 800 or 1,200 mg twice daily matching for 24 weeks. 2 77...
The conventional use of medicinal plants is in part based on the widespread belief that plant crude extracts are non-toxic. In South Africa, traditional preparations Cassipourea flanaganii used to treat hypermelanosis have accordingly been regarded by many as Whether so impacts potential bark be developed a commercial drug treathypermelanosis, given their documented capacity inhibit tyrosinase activity. Our study investigated acute and subacute toxicity methanol extract C. rats. Wistar rats...
The distribution of total aflatoxin (AFT) and cyclopiazonic acid (CPA) between conidia mycelial matrix was studied in five isolates Aspergillus flavus Link cultured on maize grain for 20 days at 30°C. Total CPA production differed the with F2R4FP 1–5 producing most AFT (conidia—0.245 μg/g; matrix—83 μg/g) (conidia—0.091 matrix—37 μg/g). by this isolate compared liquid (malt‐extract‐yeast‐extract‐glucose) solid substrates (yeast extract sucrose agar maize) ratio AFT:CPA decreased from 16.6:1...
Introduction: A significant number of the South African population still rely on traditional medicines (TM) for their primary healthcare. However, little to no scientific data is available effects most TM products cytokine and cellular biomarkers immune response. We evaluated impact a [Product Nkabinde (PN)] in inducing response peripheral blood mononuclear cells (PBMCs). Methods: PN, combination four indigenous plants was used this study. The IC 50 established using cell viability assay...