A5075189681- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Biomedical Ethics and Regulation
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
- Ethics in Clinical Research
- Photoreceptor and optogenetics research
- Child and Adolescent Health
- Pharmaceutical studies and practices
- Genomics and Rare Diseases
- Advanced NMR Techniques and Applications
- Memory and Neural Mechanisms
- International Development and Aid
- Receptor Mechanisms and Signaling
- Molecular spectroscopy and chirality
- Respiratory Support and Mechanisms
- Artificial Intelligence in Healthcare and Education
- Cardiac electrophysiology and arrhythmias
- Neuroscience and Neural Engineering
- Adolescent and Pediatric Healthcare
Universidade Nova de Lisboa
1991-2023
University of Lisbon
2023
Nova Medical (United States)
1992
Abstract Ethical review systems need to build on their experiences of COVID-19 research enhance preparedness for future pandemics. Recommendations from representatives over twenty countries include: improving relationships across the ecosystem; demonstrating willingness reform and adapt processes; making case robustly better resourcing.
Abstract Background The COVID-19 pandemic has had a devastating impact on multiple aspects of healthcare, but also triggered new ways working, stimulated novel approaches in clinical research and reinforced the value previous innovations. Conect4children (c4c, www.conect4children.org ) is large collaborative European network to facilitate development medicines for paediatric populations, made up 35 academic 10 industry partners from 20 countries, more than 50 third parties, around 500...
Advice from multiple stakeholders is required to design the optimal pediatric clinical trial. We present recommendations for acquiring advice trial experts and patients/caregivers, derived meetings that were performed through a collaboration of Collaborative Network European Clinical Trials Children (c4c) Patient-CEntric ClinicAl TRial PLatforms (EU-PEARL). Three performed: (1) an meeting methodology experts, (2) (3) combined with both patients/caregivers. Trial recruited c4c database....
The postnatal evolution of the signals underlying afterhyperpolarization (slow-AHP and medium-AHP) was studied in rat CA1 hippocampal neurones (P10-16, P17-23 P greater than 26) using vitro slices. Noradrenaline (NA) signal subtraction were used to decompose AHP (m-AHP s-AHP). amplitude s-AHP found significant between P10-16 cells; m-AHP showed no change. time peak 26 cells be significantly different from remaining groups; changes waveform at this stage mainly due modifications slow-AHP.
<h3>Background</h3> The Biomedical Ethics and Regulatory Capacity Building for Portuguese Speaking African Countries Project (BERC-Luso) was a four-year initiative that aimed to enhance biomedical ethics regulatory capacities in Angola, Cape-Verde, Guinea Bissau, Mozambique, São Tomé Príncipe, Portugal. project established network of National Committees (NCEs), Authorities (NRAs), experts research, developed comparative legislative study, created educational programs promote capacity...
BERC-Luso is a project for building Ethics and Regulatory Capacity, to be developed in four sub-Saharan African countries: Angola, Guinea-Bissau, Mozambique Cape Verde, implemented 2018–2021. National Committees (NECs) Authorities (NRAs) have been engaged (6 institutions) with the partnership of 4 Portuguese institutions (experts ethical review regulatory supervision). Considering that: 1) clinical trials are fundamental improve healthcare develop biomedical research; but 2) can only take...
Objective: to identify the main innovative aspects of Regulation on clinical trials medicines for human use, in terms opportunities research and development reflect ethical challenges this new legal framework. Methods: documentary, descriptive, comparative study regard with Directive 2001/20/EC, reading bibliography published PubMed, using combined or simple such as clinical, trials, European, Regulation, Directive, opportunities, innovation. Results: identified were Portal submission trial...