A5089416078- Environmental Toxicology and Ecotoxicology
- Nanoparticles: synthesis and applications
- Insect Pest Control Strategies
- Insect Resistance and Genetics
- Graphene and Nanomaterials Applications
- Heavy metals in environment
- Insect Utilization and Effects
- Insect and Pesticide Research
- Pesticide Exposure and Toxicity
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Glutathione Transferases and Polymorphisms
- Insect and Arachnid Ecology and Behavior
- Minerals Flotation and Separation Techniques
- Neurobiology and Insect Physiology Research
- Selenium in Biological Systems
- Microplastics and Plastic Pollution
- Diet and metabolism studies
- Heavy Metals in Plants
- Bone Tissue Engineering Materials
- X-ray Spectroscopy and Fluorescence Analysis
- Genetics, Aging, and Longevity in Model Organisms
- Metal Extraction and Bioleaching
- Bee Products Chemical Analysis
- Carbon and Quantum Dots Applications
University of Silesia in Katowice
2015-2024
A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was successfully synthesized, characterized, evaluated for their antimicrobial responses. The synthesized compounds were obtained utilizing N-alkylation 1,3-dipolar cycloaddition reactions, as well structures established through spectroscopic methods confirmed by mass spectrometry. To get more light on the regioselective synthesis hybrid compounds, mechanistic studies performed using DFT calculations with...
This work aimed to evaluate the inhibitory effect of main polyphenols and flavonoids Syzygium aromaticum Citrus limon as well organosulfur compounds Allium sativum against SARS-CoV-2 6LU7 6Y2E proteases using in silico molecular docking analysis. Structures 34 natural products found three medicinal plants were docked these two critical proteins. For protease, 24 exhibited binding affinities greater than or equal -6 Kcal/mol. While, for 6 Molecules with a maximum affinity -8.4 kcal/mol show...
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic field in medicinal chemistry. In this context, series of spiropyrazoline indolin-3-one congeners were assessed their vitro bioactivities, in-silico studies conducted to support the experimental results. screening oxindole against selected microbe strains (Staphylococcus aureus (CECT 976), Bacillus subtilis (DSM 6633), Escherichia coli (K12), Candida albicans (ATCC 10231)) exhibited moderate excellent,...
Attenuation of adverse effects aflatoxin (AFB1) in brains B1 rats by extracts leaves artichoke was studied. The active ingredients artichoke, Cynara scolymus L., were determined HPLC analysis. In the 42-day experiment, exposed to either sterile water, 4% DMSO, 100 mg leaf extract/kg body mass, 72 μg B1/kg or AFB1 plus extract. Neurotoxicity an increase profile lipids, augmentation plasmatic glucose and concentrations insulin, oxidative stress, increased activities cholinergic enzymes, a...
Honeybee products arouse interest in society due to their natural origin and range of important biological properties. Propolis (P) royal jelly (RJ) attract scientists' attention because they exhibit antioxidant, anti-inflammatory, anti-bacterial, anti-tumor, immunomodulatory abilities. In this study, we tested whether P RJ could mitigate the adverse effects cadmium (Cd) exposure, with particular emphasis on reproductive function female rats. line, one week pretreatment was established. Six...
The advancement of nanotechnology poses a real risk insect exposure to nanoparticles (NPs) that can enter the digestive system through contaminated food or nanopesticides. This study examines whether model species—Acheta domesticus—to increasing graphene oxide (GO) and silver nanoparticle (AgNP) concentrations (2, 20, 200 ppm 4, 40, 400 ppm, respectively) could change its functions: enzymes’ activities, consumption, assimilation. We noticed more pronounced alterations following AgNPs than...
In the case of pests inhabiting metal polluted or fields where use pesticides is common, a natural selection resistant individuals can occur. This may pose serious problems for humans, agriculture, as well economies many countries. this study, hypothesis that multigenerational (120 generations) exposure to cadmium beet armyworm population could be selecting factor toward more efficient DNA protection was verified. The hemocytes from two culture strains (control and Cd-exposed) were treated...