A5067263273- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Renal and related cancers
- Urinary Bladder and Prostate Research
- Cancer Genomics and Diagnostics
- Urologic and reproductive health conditions
- Testicular diseases and treatments
- Bladder and Urothelial Cancer Treatments
- Hormonal and reproductive studies
- Sarcoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Patient Satisfaction in Healthcare
- Cancer Research and Treatments
- Immunotherapy and Immune Responses
- Cancer, Lipids, and Metabolism
- Pediatric Urology and Nephrology Studies
- Cancer Cells and Metastasis
- Urinary and Genital Oncology Studies
- Pelvic floor disorders treatments
- Healthcare Policy and Management
- Medical and Health Sciences Research
- Sexual function and dysfunction studies
- Photodynamic Therapy Research Studies
- Multiple Myeloma Research and Treatments
Texas Tech University Health Sciences Center
2015-2024
Texas Tech University
2015-2024
Lubbock Christian University
2015
Otto-von-Guericke University Magdeburg
2007-2009
West Cancer Center
2009
Leipzig University
2003
Ruhr University Bochum
1994-1995
Indiana University – Purdue University Indianapolis
1993-1995
Indiana University School of Medicine
1995
Universitätsklinik Marien Hospital Herne
1994-1995
Purpose: To prospectively assess potential risk factors for relapse in clinical stage I nonseminomatous germ cell tumors of the testis (CS NSGCT). Patients and Methods: From September 1996 to May 2002, 200 patients with CS NSGCT were assigned retroperitoneal lymph node dissection (RPLND), factor assessment was performed within a multicenter protocol. One hundred sixty-five had an adequate minimum follow-up 12 months (mean, 34.5 months) or pathologic II. Results: Pathologic II disease found...
Using G-banding technique, the chromosomes were studied in short-term cultures of 25 primary renal-cell carcinomas (RCC). Phytohaemagglutinin-stimulated peripheral blood lymphocytes or normal kidney cells same patients growing analysed to define constitutional karyotype. The modal chromosome number 23 RCC's was found be pseudo-diploid near-diploid with only few structural rearrangements, 22 showed an aberration 3, deletion 3p, translocation different segments deleted leading loss variable 3....
Abstract We describe a German family carrying constitutional translocation (3;6) (p13;q25.1) in 3 consecutive generations. The only member of the over 50 years age and developed multiple bilateral renal cell carcinomas. performed chromosome analysis 4 out 5 primary tumours, which were characterized by different clonal karyotypes. constitutionally translocated 3p13‐pter segment was lost with or without receptor 6 each tumour. Additional karyotypic changes trisomy 5, 7 18, monosomy 14 21, loss...
Journal Article Differentiation Between Papillary and Nonpapillary Renal Cell Carcinomas by DNA Analysis Get access Gyula Kovacs, Kovacs * Lab-oratory of Cytogenetics, Institute Pathology, Albert-Ludwigs-University, Fed-eral Republic Germany.Freiburg *Correspondence to: Dr. Albert Str. 19, D-7800 Freiburg, Federal Germany Search for other works this author on: Oxford Academic PubMed Google Scholar Ludwig Wilkens, Wilkens Thilo Papp, Papp Werner de Riese Department Urology, HannoverMedical...
The aim of this study was to investigate the possible correlation between prostate volume and aggressiveness incidence cancer (PCa).A chart review a cohort 448 consecutive biopsy-naive men performed. These underwent at least 12-core biopsy our institution due increased prostate-specific antigen serum levels (>4 ng/mL) and/or suspicious findings on digital rectal examination during period 2008 2013. Transrectal ultrasound used determine volume.The positive rate 66% for patients with ≤35 cc...
Purpose: Studies have shown that finasteride may decrease the incidence of prostate cancer (PCa) in general but increase high-grade PCa. There been conflicting hypotheses attempting to explain this phenomenon. This is first study stratifying Prostate Cancer Prevention Trials (PCPT) data based on volume as a moderating variable Materials and methods: Patients from both control group treatment arm PCPT were included analysis. Inclusion criteria consisted patients with documented biopsies...
PURPOSE Fresh tissue samples from nonmetastatic renal cell carcinoma (RCC) patients were analyzed by Ki-67 immunostaining to determine the prognostic significance of this tumor-biologic parameter. MATERIALS AND METHODS In a prospective study, was performed on frozen sections histologically proven node-negative RCC 58 operated between 1986 and 1988 examine method's value its association with other clinicopathologic parameters such as tumor stage (pT) grade (G). RESULTS The percentage...
Although inflammation and prostate cancer (PCa) have been linked, the molecular interactions between macrophages PCa cells are poorly explored. Pigment Epithelium-Derived Factor (PEDF) is an anti-angiogenic anti-tumor factor. We previously showed that PEDF induces recruitment in vitro, correlates with density human prostate, stimulates polarization towards classically activated pathway. Here, we demonstrate modulates interaction through a bidirectional signalling leading to tumor cell...
No AccessJournal of Urology1 Sep 1991Single Potential Analysis Cavernous Electrical Activity in Impotent Patients: A Possible Diagnostic Method for Autonomic Dysfunction and Smooth Muscle Degeneration Christian G. Stief, Mohamad Djamilian, Peter Anton, Werner de Riese, Ernst P. Allhoff, Udo Jonas StiefChristian Stief , DjamilianMohamad Djamilian AntonPeter Anton RieseWerner Riese AllhoffErnst Allhoff JonasUdo View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)37918-1AboutPDF...
A detailed G-banded chromosome analysis was performed in primary cell cultures obtained from two renal oncocytomas. Both tumors were characterised by clonal aberrations. One had a stemline karyotype 45,X,-X,rcp(8;19),der(13)t(X;13) and several sidelines with variant additional The of the other neoplasm revealed pseudodiploid 46,XY,del(1q),der(13)t(1;13) cells normal karyotype; both types showed telomeric associations chromosomes, formed mostly smaller chromosomes. pattern oncocytomas is...
In this study, we investigated the capacity of pigment epithelium-derived factor (PEDF) to modulate recruitment and differentiation monocytes/macrophages both in vitro human prostate.Using Boyden chambers, assessed PEDF effect on migration monocytes chemically activated RAW 264.7 macrophages. Normal, prostatitis, prostate cancer specimens were retrospectively selected examined by immunohistochemistry for expression infiltration immune CD68 + macrophagic cells. macrophage density then...
There is currently no cure for advanced castration-refractory prostate cancer (CRPC) despite the recent approval of several new therapeutic agents. We report here anti-tumor effect angio-inhibitory pigment epithelium-derived factor (PEDF) in metastatic LNCaP-derivative CRPC CL1 model and explore PEDF anti-neoplasic efficacy combination with low-dose chemotherapy. Androgen-sensitive LNCaP PC3 cell lines were examined as comparison. Using a retroviral expression system, we showed that limited...