A5011550854- Poisoning and overdose treatments
- Forensic Toxicology and Drug Analysis
- Opioid Use Disorder Treatment
- Psychedelics and Drug Studies
- Cannabis and Cannabinoid Research
- Epilepsy research and treatment
- Venomous Animal Envenomation and Studies
- Anesthesia and Sedative Agents
- Alcoholism and Thiamine Deficiency
- Pharmaceutical studies and practices
- Methemoglobinemia and Tumor Lysis Syndrome
- Pharmacological Effects and Toxicity Studies
- Cardiac electrophysiology and arrhythmias
- Rabies epidemiology and control
- Prenatal Substance Exposure Effects
- Neurotransmitter Receptor Influence on Behavior
- Electroconvulsive Therapy Studies
- Alcohol Consumption and Health Effects
- Toxin Mechanisms and Immunotoxins
- Nicotinic Acetylcholine Receptors Study
- Sleep and related disorders
- Renal function and acid-base balance
- Complementary and Alternative Medicine Studies
- Animal testing and alternatives
- Drug-Induced Hepatotoxicity and Protection
University of Kansas
2012-2025
University of Kansas Medical Center
2013-2024
Oregon Health & Science University
2021
The University of Kansas Health System
2012-2020
Children's Mercy Hospital
2014-2020
University Health System
2019
University of California San Diego Medical Center
2011-2015
University of California, San Diego
2011-2014
Washington Poison Center
2013
Beaumont Hospital, Troy
2013
Ivabradine was approved for use in the United States 2015 management of heart failure. It acts through inhibition sodium channels found cardiac myocytes (the "funny" pacemaker current, If), which reduces rate without significantly affecting inotropy. We queried National Poison Data System® reported ivabradine exposures from April 15, 2015-December 31, 2023. Age stratified into child (0-5 years), adolescent (6-17 adult (18-64 years) and geriatric (65+ years). Other descriptive statistics...
To analyze the contents of "bath salt" products purchased from California stores and Internet qualitatively quantitatively in a comprehensive manner.A convenience sample were person by multiple authors at retail six cities over (U.S. sites only), between August 11, 2011 December 15, 2011. Liquid chromatography-time-of-flight mass spectrometry was utilized to identify quantify all substances products.Thirty-five analyzed. Prices ranged $9.95 49.99 dollars). Most had warning against use. The...
This case report is considered exempt from University of California-San Diego Investigational Review Board.Introduction. There a limited published experience detailing detection and toxicity multiple novel psychoactive substances. We patient with prolonged psychosis who had JWH-072, cannabicyclohexanol, 3’,4’-methylenedioxy-α-pyrrolidinopropiophenone (MDPPP) methylenedioxyamphetamine (MDA) identified in biological samples. Case details. An 18-year-old man presented to the emergency...
A microfluidic sensor was studied for the photometric detection of active chlorine, total and pH in swimming pool samples. The consisted a four-layer borosilicate glass chip, containing microchannel network 2.2 mm path length, 1.7 mL optical cell. chip optimised to measure bleaching methyl orange spectral changes phenol red quantitative chlorine (active total) measurements that were suited monitoring. Reagent consumption (60 per measurement) minimised allow maintenance-free operation over...
Abstract Objective: To document women's experiences of admission to hospital with a pregnancy‐related complication, hypertension, from their own perspective. Methods: Qualitative descriptive study. The views 12 women admitted hypertension were obtained through semi‐structured interviews. Issues explored included understanding the condition, information needs, expectations and beliefs. Results: Women searching for an explanation help make sense situation. Some faced paradox being (thus...
Ingestions of the seed castor bean plant (Ricinus communis) carries risk toxicity from ricin, a potent inhibitor protein synthesis.We sought to describe characteristics exposures reported state-wide poison control system.This was an observational case series. A system's database reviewed for seeds 2001 2011. Case notes were and data collected, when available, included age, gender, circumstances surrounding exposure, number beans consumed, whether chewed or crushed, symptoms described,...
Methoxetamine and 3-methoxy-phencyclidine are novel arylcyclohexylamines whose use clinical toxicity poorly reported in the medical literature. We report a case of analytically confirmed both methoxetamine 3-methoxy-phencyclidine.A 27-year-old male presented 10 hours after insufflating an Internet-obtained powder. He was hypertensive, tachycardic, demonstrated dissociated affect, delayed verbal response to questions, ataxia, vertical nystagmus. A urine drug screen positive for phencyclidine...
Background and aims The Psychoactive Surveillance Consortium Analysis Network (PSCAN) is a national network of academic emergency departments (ED), analytical toxicologists pharmacologists that collects clinical data paired with biological samples to identify improve treatments medical conditions arising from use new psychoactive substances (NPS). aim this study was gather drug identification NPS users who presented EDs within PSCAN during its first year (2016–17). Design Observational...
Abstract Objectives North American coral snake envenomations can result in life‐threatening neurotoxicity. Their bites are relatively rare, making large studies difficult. Using the National Poison Data System (NPDS), we sought to investigate epidemiological trends and clinical outcomes associated with over a 17‐year period. Methods NPDS cases involving snakes from January 1, 2006, December 31, 2022, were analyzed. collected included patient age, date, geographic location, effects,...
Context: Multiple studies have concluded that urine drug screens rarely change clinical management. The rapid comprehensive screen (RCUDS) at our institution detects over 300 substances using a combination of EIA and GC/MS typically takes 2–5 h for completion.Objective: We sought to determine whether this RCUDS altered management in the pediatric population.Methods: All patients >1 month <18 years age which was completed from 1 January 2012 31 December were eligible study. Assuming would not...
BACKGROUND Envenomation from the brown recluse spider (Loxosceles reclusa) is described to cause both local and systemic symptoms. We report a case of an adolescent boy who developed severe loxoscelism, his clinical course was complicated by myocarditis, which has not been previously reported in association with loxoscelism. CASE REPORT A 16-year-old presented non-specific symptoms forearm pain following suspected bite, subsequently evolved into necrotic skin lesion. During course, he...
Donepezil and memantine are commonly prescribed antidementia drugs. There is a paucity of literature concerning pediatric ingestions these We describe case 2-year-old child who developed encephalopathy after an unintentional ingestion donepezil memantine. A girl was found by her family members agitated reporting visual hallucinations. In the emergency department, she became sedated had rightward eye deviation. She hospitalized extensive neurological infectious disease testing that...