A5003419260- Voice and Speech Disorders
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Head and Neck Cancer Studies
- Phonetics and Phonology Research
- Family Support in Illness
- Microbial Metabolism and Applications
- Meningioma and schwannoma management
- Gold and Silver Nanoparticles Synthesis and Applications
- Neurofibromatosis and Schwannoma Cases
- Cancer survivorship and care
- Speech Recognition and Synthesis
- Cardiac tumors and thrombi
- Esophageal and GI Pathology
- Ginkgo biloba and Cashew Applications
- Oral health in cancer treatment
- Ear Surgery and Otitis Media
- Phytochemistry and biological activity of medicinal plants
- Glycosylation and Glycoproteins Research
- Vascular Malformations Diagnosis and Treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Trauma and Emergency Care Studies
- Head and Neck Surgical Oncology
- Pharmacological Effects of Natural Compounds
- Advanced Biosensing Techniques and Applications
Yale University
2025
Texas Tech University
2024
University of Washington
2023-2024
Colorado Permanente Medical Group
2021-2023
Kaiser Permanente Santa Clara Medical Center
2021-2023
Mount Sinai Health System
2020-2021
University of California, San Francisco
2012-2020
Maimonides Medical Center
2020
Chang Gung Memorial Hospital
2010-2018
Linkou Chang Gung Memorial Hospital
2004-2018
Oral cancer patients' supportive care needs during the postoperative period can impact their family caregivers' burden. The purposes of this study were to (1) examine perceived levels needs, (2) caregiving burden, and (3) predictive factors for burden with newly diagnosed oral patients period. A cross-sectional, correlational was conducted. One hundred twenty-two pairs eligible caregivers recruited from otolaryngology plastic/reconstructive inpatient wards in a medical center northern...
Objective The aim of this study was to identify factors associated with unmet supportive care needs in family caregivers patients oral cancer after surgery. Methods In a cross-sectional study, we recruited patient–family caregiver dyads from the otolaryngology head and neck surgery wards medical center northern Taiwan. Patients were assessed using set structured questionnaires measure symptom distress, sleep quality, depression. Social support measured. Results Of 102 surveyed, for...
Abstract BACKGROUND The optimal observation interval after the radiosurgical treatment of a sporadic vestibular schwannoma, prior to salvage intervention, is unknown. OBJECTIVE To determine an postradiosurgical for differentiating between pseudoprogression and true tumor growth by analyzing serial volumetric data. METHODS This single-institution retrospective study included all schwannomas treated with Gamma Knife radiosurgery (Eketa AB, Stockholm, Sweden; 12–13 Gy) from 2002 2014....
Objectives/Hypothesis VT is often considered the preferred treatment for vocal feminization in transgender patients. However, Wendler glottoplasty offers a surgical option increasing fundamental frequency and perception of femininity. We aimed to determine whether addition results greater elevation improvement quality‐of‐life measures. Study Design Retrospective case series. Methods Forty‐eight trans female patients were treated feminization. Twenty‐seven underwent VT, 21 with additional...
Processing faces and speech is supported by the right-lateralized social visual perception pathway (social pathway) involving medial temporal/visual 5 area (MT/V5) superior temporal sulcus (STS). Little known about development of its links with later outcomes. We examined intrinsic functional connectivity (iFC) in right neurotypical neonates, compared it iFC left bilateral dorsal attention pathways, interrogated prospective between neurodiverse neonates. pathways was measured 517 full-term...
We demonstrate the capability of using immunotargeted gold nanoshells as contrast agents for in vitro two-photon microscopy. The luminescence properties different-sized are first validated near-infrared excitation at 780 nm. utility microscopy a tool imaging live HER2-overexpressing breast cancer cells labeled with anti-HER2-conjugated is then explored and results compared to normal cells. Five different channels simultaneously examined within emission wavelength range 451–644 Our indicate...
Objective The purpose of this study was to evaluate the effects a skin camouflage program on disfigurement, self-esteem, social interaction, and body image in female head neck cancer (HNC) survivors. Methods A prospective, repeated-measures, randomized controlled therapeutic intervention design used. total 66 participants were randomly assigned each group, with 32 experimental group 34 control group. received 4-session program, routine care. Patients assessed at 3 time points: baseline...
Objectives/Hypothesis Topical mitomycin‐C (MMC) application is a commonly accepted adjuvant therapy in the surgical treatment for laryngotracheal stenosis (LTS). However, efficacy of MMC has not been examined prospective, randomized clinical trial humans. We aimed to examine LTS patients as compared placebo‐controlled group. Study Design Prospective, randomized, double‐blind, trial. Methods Fifteen with were enrolled 24‐month and into one two groups: 1) endoscopic topical or 2) saline....
Abstract: The anticancer properties of tea catechins are most frequently attributed to the principal catechin (‐)‐epigallocatechin‐3‐gallate (EGCg). Efficacy was evaluated using growth cultured HeLa cells and inhibition enzymatic activity a putative cell surface target enzyme, cancer‐associated surface‐located NADH oxidase (ECTO‐NOX) designated tNOX. amounts EGCg required inhibit by both criteria reduced 10 times combination with inactive such as (‐)‐epicatechin (EC), (‐)‐epigallocatechin...
A Soluble sialidase that can degrade recombinant glycoproteins expressed in Chinese hamster ovary (CHO) cells has been isolated and purified to near homogeneity from the cell culture fluid of this host. Purification ∼34 000-fold was carried out using conventional purification techniques including sequential DEAE—Sepharose S-Sepharose ionexchange chromatography, followed by hydrophobic interaction chromatography with Phenyl-Toyopearl. Final achieved heparin—agarose chromatofocusing...
To evaluate the effect of medialization laryngoplasty (ML) performed alone compared to ML with arytenoid adduction (AA) on glottic gap and voice quality in unilateral vocal fold paralysis (UVFP) patients.Retrospective case series.UVFP patients treated AA at University California San Francisco Voice Swallowing Center were identified. Demographic information history laryngeal procedures collected. Preoperative postoperative examinations digitally analyzed using ImageJ for normalized anterior...
Fear of cancer recurrence (FCR) is a major concern for family caregivers (FCs) caring patients with head and neck cancers (HNCs).This study (a) investigated the FCR experience HNC FCs, (b) compared differences in levels FCs while taking care different lengths time since completing treatments (posttreatment durations), (c) examined correlation between quality life (QOL) these FCs.A cross-sectional was conducted radiation outpatient department medical center northern Taiwan. A set...
Objective Differentiating pseudoprogression from true tumor growth is a difficult clinical problem in the management of vestibular schwannomas after radiosurgery. Controversy exists regarding how much tolerance clinician should have for enlargement following treatment, before recommending salvage therapy. In this study, we sought to describe distribution volume behaviors radiosurgery, identify factors associated with transient growth, and an ideal timeframe differentiating pseudoprogression.
Objectives Voice therapy has been the primary treatment for voice feminization in transfemale patients due to concerns that surgery worsens quality. We aim determine impact of Wendler glottoplasty on acoustic measures voice. Study Design Retrospective case series. Methods Transgender female treated vocal with at a single tertiary care center were identified. Pre‐ and postoperative taken Kay Elemetrics Real‐Time Pitch, Analysis Dysphonia Speech Voice, Multidimensional Program. Results...
To date, 1-year evaluation of pitch elevation in patients undergoing modified Wendler glottoplasty (WG) combination with VT has not been assessed.To determine whether is sustained who undergo WG for voice feminization.A retrospective review underwent therapy (VT) was performed from 2016 to 2020. Charts were reviewed vowel fundamental frequency (F0/a/), speaking (SF0), and Trans Woman Voice Questionnaire (TWVQ) at preoperative, initial postoperative (3-6 months after surgery), 12-month...
Objectives/Hypothesis To evaluate the effect of radiation therapy on voice outcome and duration calcium hydroxylapatite (CaHA) injection laryngoplasty in unilateral vocal fold paralysis (UVFP) patients. Study Design Retrospective case series. Methods UVFP patients treated with CaHA at University California San Francisco Voice Swallowing Center were identified. Demographic information, history irradiation to larynx, time additional medialization procedures obtained. Examinations presentation...