A5041780010- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Machine Learning in Bioinformatics
INTI International University
2023-2024
Alrafidain University College
2024
National University of Malaysia
2023
A previous study has shown that synthetic antimicrobial peptides (AMPs) derived from Anabas testudineus (ATMP1) could in-vitro inhibit the progression of breast cancer cell lines. In this study, we are interested in studying altered versions AMPs to gain some insight into functions. The were and subjected bioinformatics prediction using four databases (ADP3, CAMP-R3, AMPfun, ANTICP) select highest anticancer activity. silico analysis led selection two AMPs, which ATMP5...
Various studies have demonstrated that directed evolution is a powerful tool in enhancing protein properties. In this study, was used to enhance the efficacy of synthesised Anabas testudineus AtMP1 antimicrobial peptides (AMPs) inhibiting proliferation cancer cells. The modification and prediction peptide properties using bioinformatic tools were carried out four databases, including ADP3, CAMP-R3, AMPfun, ANTICP. One modified (AMP), ATMP6 (THPPTTTTTTTTTTTTTAAPARTT), chosen based on its...