- Air Quality and Health Impacts
- Heme Oxygenase-1 and Carbon Monoxide
- Vanadium and Halogenation Chemistry
- Climate Change and Health Impacts
- Olfactory and Sensory Function Studies
- Biochemical effects in animals
- Malaria Research and Control
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Heavy Metal Exposure and Toxicity
- Neurological Disease Mechanisms and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Carcinogens and Genotoxicity Assessment
- Educational Research and Science Teaching
- COVID-19 Clinical Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Soft tissue tumor case studies
- Aldose Reductase and Taurine
- Metastasis and carcinoma case studies
- Higher Education Teaching and Evaluation
- Advanced Glycation End Products research
- Traditional and Medicinal Uses of Annonaceae
- Adipokines, Inflammation, and Metabolic Diseases
- Health and Medical Education
- Protease and Inhibitor Mechanisms
- Air Quality Monitoring and Forecasting
Universidad Nacional Autónoma de México
2011-2024
Universidad Autónoma de la Ciudad de México
2019
Kidney diseases have notably increased in the last few years. This is partially explained by increase metabolic syndrome, diabetes, and systemic blood hypertension. However, there a segment of population that has neither previous risk factors, yet suffers kidney damage. Exposure to atmospheric pollutants been suggested as possible factor. Air-suspended particles carry on their surface variety fuel combustion–related residues such metals, vanadium one these. Vanadium might produce oxidative...
Carnosine (β-alanyl-L-histidine) is synthesized in the olfactory system, has antioxidant activity as a scavenger of free radicals and been reported to have neuroprotective action diseases which attributed oxidative damage. In neurodegenerative disorders, such Parkinson's Alzheimer's diseases, impairment function described. Vanadium derivatives are environmental pollutants, its toxicity associated with stress. on bulb was previously. This study investigates effect carnosine mice model...
Neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases, have olfaction impairment. These pathologies also been linked to environmental pollutants. Vanadium is a pollutant, its toxic mechanisms are related the production of oxidative stress. In this study, we evaluated effects inhaled vanadium on olfaction, olfactory bulb antioxidant, through histological ultrastructural changes in granule cells. Mice control group were made inhale saline; experimental 0.02-M pentoxide (V 2...
Abstract Vanadium (V) derivatives are well‐known environmental pollutants and its toxicity has been related with oxidative stress. Toxicity after vanadium inhalation on the substantia nigra, corpus striatum, hippocampus ependymal epithelium was reported previously. The purpose of this study to analyse role matrix metalloproteinases 2 (MMP‐2) 9 (MMP‐9) in changes observed brain tissue chronic V inhalation. Mice were exposed vaporized, pentoxide 0.02 m deionized water for 1 h twice a week,...
Vanadium (V) is an air pollutant released into the atmosphere by burning fossil fuels. Also, it has been recently evaluated for their carcinogenic potential to establish permissible limits of exposure at workplaces. We previously reported increase in number and size platelets precursor cells megakaryocytes bone marrow spleen. The aim this study was identify involvement Janus kinase/signal transducers activators transcription (JAK/STAT) pathway thrombopoietin (TPO) receptor,...
Environmental pollution can promote oxidative stress by exposing the body to various elements and substances that generate free radicals, such as lead vanadium. These radicals negatively impact respiratory, cardiovascular, immune, neurological systems of vulnerable populations, including children, elderly, those with chronic diseases. To prevent or reduce stress, it is recommended consume a balanced diet rich in natural antioxidants. antioxidants be found foods, especially fruits vegetables...
El megacariocito es la celula mas grande de medula osea, por lo tanto relativamente facil reconocer su presencia al observar un aspirado o una biopsia este tejido. Difiere otras celulas tamano, ser poliploide y crecer endomitosis. No hay otra humana que crezca asi. Ademas, tiene funciones biologicas muy importantes. La conocida el dar origen a las plaquetas, son indispensables para hemostasia reparacion los vasos sanguineos danados, asi como cicatrizacion tejidos rodean heridas. Sin embargo,...
Vanadium is a metal present in particulate matter and its reprotoxic effects have been demonstrated males pregnant females animal models. However, the of this on reproductive organs nonpregnant not sufficiently studied. In vanadium inhalation model female mice, we found anestrous estrous cycle irregularity, as well low serum concentrations 17β-estradiol progesterone. A decrease diameter secondary preovulatory follicles, thickening myometrium endometrial stroma, was observed vanadium-treated...
The Non-Ciliated Bronchiolar Cell (NCBC) is responsible for the defense and maintenance of bronchiolar epithelium. Several cellular mechanisms have been associated with an increase in secretion CC16 changes phenotype cell; these could be linked to tolerance damage due exposure inhaled Particulate Matter (PM) These not sufficiently explored. In this article, we studied response NCBC vanadium, element which adheres PM. This was measured by a mouse model. Mice were exposed two phases different...
Vanadium (V) adhering to inhaled particles has been associated with male reproductive alterations. Intercellular junction proteins, such as connexin 43, constitute the blood-testes barrier. These proteins are crucial for reconstitution of barrier during spermatogenesis. Normally, connexins located between cell membranes but in cells exposed certain metals or which transformed, their location is altered. The objective this study was examine effect inhalation vanadium pentoxide on distribution...
Particulate matter air pollution has considerably increased during the last decades; vanadium is a transition element adhered to this particulate matter, and combustion of fossil fuels main source in atmosphere. It been reported that specifically exposure increases probability suffering arrhythmias; however biological mechanism such relationship remains unknown. established diminished presence N-Cadherin alters Connexin-43 arrangement, consequent altered these proteins predisposes...
It is estimated that the human body made of trillions cells, which suffer hundreds thousands DNA lesions every day. Although not only biomolecule suffers damage, its importance lies in fact it cannot be replaced by cell, so when cell must repair it, tolerate or, a extreme case, activate pathways will lead to death, since objective maintain integrity and homeostasis organism.There are agents can damage DNA, some produced called 'endogenous, while others external known as 'exogenous. The avoid...
The non-ciliated bronchiolar cell, also referred to as "club cell", serves a significant multifunctional component of the airway epithelium. While club cell is prominent epithelial type found in rodents, it restricted bronchioles humans. Despite these differences, cell's importance remains undisputed both species due its multifunctionality regulatory lung inflammation and stem regeneration. objective this review examine different aspects morphology physiology epithelium, under normal...
La contaminación atmosférica es uno de los grandes problemas a nivel global. Dentro contaminantes ambientales más importantes están las partículas suspendidas, cuales han sido clasificadas dentro del Grupo 1 como carcinógenas para humanos por la Agencia Internacional sobre Investigación en Cáncer. A suspendidas se adosan componentes con relevancia toxicológica metales que les atribuyen, al menos parte, efectos adversos generan organismos. Uno presentes el vanadio, metal encuentra elemento...