A5024012351- COVID-19 Clinical Research Studies
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ovarian function and disorders
- Long-Term Effects of COVID-19
- Cardiovascular Health and Risk Factors
- Chronic Disease Management Strategies
- Pancreatitis Pathology and Treatment
- Diabetes and associated disorders
- Birth, Development, and Health
- Adipokines, Inflammation, and Metabolic Diseases
- Dietary Effects on Health
- Diet and metabolism studies
- Reproductive Biology and Fertility
- Genetics, Aging, and Longevity in Model Organisms
- Diet, Metabolism, and Disease
- Hormonal and reproductive studies
- Growth Hormone and Insulin-like Growth Factors
- Neurological Disorders and Treatments
- Lipid metabolism and disorders
- Medical Research and Treatments
- Pancreatic function and diabetes
- Bariatric Surgery and Outcomes
- Nutrition and Health in Aging
- Pregnancy and preeclampsia studies
University Medical Center
2022-2024
Astana Medical University
2016-2024
Kazakhstan Medical University
2024
University Hospital and Clinics
2022
Nazarbayev University
2017-2022
University of British Columbia
2022
Republican Center for Healthcare Development
2016
Antrim Area Hospital
2016
Surrey and Sussex Healthcare NHS Trust
2016
Abstract Background We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) investigate demographic factors comorbidities associated with all-cause mortality by aggregating utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) Kazakhstan for 2014–2019 years period. Methods A total 475,539 individuals were included in analyses. The median follow-up Type 1 DM patients accounted 4.7 4.5 2 patients. used...
Polycystic Ovarian Syndrome (PCOS) is a common endocrine condition that affects 8–13% of women reproductive age and one the leading causes anovulation infertility. In Kazakhstan, prevalence this syndrome particularly high compared to other countries global average. Currently, diagnosis polycystic ovarian based on internationally established Rotterdam criteria, using hyperandrogenism, i.e. testosterone levels, as key parameter. These criteria are applied diagnose PCOS in all female patients,...
COVID-19 comorbid with noncommunicable chronic diseases (NCDs) complicates the diagnosis, treatment, and prognosis, increases mortality rate. The aim is to evaluate effects of a restricted diet on clinical/laboratory inflammation metabolic profile, reactive oxygen species (ROS), body composition in patients NCDs. We conducted 6-week open, pilot prospective controlled clinical trial. study included 70 adult type 2 diabetes (T2D), hypertension, or nonalcoholic steatohepatitis (NASH).
The prevalence of type 2 diabetes is increasing in worldwide despite the development new treatment methods. Aim study was to evaluate a weight loss method on body composition, glycemic, lipid and hormone profiles, blood pressure reactive oxygen species people with treated diabetes.A 24-week open, prospective, randomized, controlled clinical trial including 272 adult patients performed. were divided two groups: Main group consisted 208 who followed calorie restriction diet optimal physical...
Cardiovascular risk factors aggregate in determined individuals. Patients with Type 2 diabetes mellitus (T2DM) have higher cardiovascular This study aimed to investigate insulinresistance (IR) and β-cell function using the homeostasis model assessment (HOMA) indexes a general Kazakh population determine effect he that may on those indexes. We conducted cross-sectional among employees of Khoja Akhmet Yassawi International Kazakh-Turkish University (Turkistan, Kazakhstan) aged between 27 69...
To investigate the relationship of ovarian reserve to levels adipokines and sex hormones in reproductive-aged women with abdominal obesity.A total 157 aged 18 45 years a body mass index (BMI) more than 30 kg/m2 were examined (a study group). A control group consisted 93 18-45 BMI less 25 kg/m2. Anthropometric carbohydrate lipid metabolic parameters hormones, anti-Müllerian hormone, resistin, adiponectin investigated.The mean age participants was 33.1±6.1 that those 25-30 32.8±6.2 years. No...
To investigate the ovarian reserve and a relationship between level of anti-Müllerian hormone (AMH) with that hormones in reproductive-aged women abdominal obesity concurrent without polycystic ovary syndrome (PCOS).A total 157 aged 18 to 45 years body mass index (BMI) more than 30 kg/m2 were examined. The conventionally divided into 2 groups: 1) 20 PCOS 2) 137 this condition. Morphometric parameters, indicators carbohydrate lipid metabolism, levels hormones, including AMH, studied.The...
Abstract Background: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) investigate demographic factors comorbidities associated with all-cause mortality by aggregating utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) for 2014-2019 years period. Methods: used Kaplan-Meier log-rank test calculate failure function differences in survival age, sex, ethnicity, Type 1 2 DM. Cox proportional hazards...
While many studies compared multiple daily injections (MDI) and insulin pump therapy on various clinical outcomes, the results remain inconclusive. This multicenter retrospective cohort study included 175 patients aimed to evaluate effects of different methods including hemoglobin A1c (HbA1c), total dosage, body mass index, glomerular filtration rate, in pediatric with type 1 diabetes. In a linear mixed-effects regression analysis, statistically significant interaction between time treatment...
ABSTRACT Background The coexistence of type two diabetes (T2D) and cardiovascular diseases (CVD) in patients with overweight increases the risk macro-vascular complications. Some studies are controversial results Ramadan fasting (RF) T2D+CVD. Objective To compare different RF (antique modern) on anthropometric, glycemic, blood pressure (BP), lipids, heel bone mineral density (HBMD), ejection fraction (EF) Methods An open, 60-day, controlled, single-center, randomized clinical trial included...
Background: Polycystic Ovarian Syndrome (PCOS) is a common endocrine condition that affects 8–13% of women reproductive age. In Kazakhstan, the prevalence this syndrome particularly high compared with other countries and global average. Currently, diagnosis PCOS based on internationally established Rotterdam criteria, using hyperandrogenism as key parameter. These criteria are applied to diagnose in all female patients, although obese patients may have excess testosterone produced by adipose...
p = 0.470; and 2.38,, 0.189, respectively.Insulin was associated with significant increase in weight compared SU (0.96 vs À0.33; < 0.0001).Conclusions: In this large cohort study, intensification of metformin treatment or insulin not any difference the risk liver-related events, irrespective body weight.
Abstract Background COVID-19 in comorbidity with non-communicable chronic diseases (NCDs) complicate the diagnosis, treatment, prognosis, and increase mortality rate. Objective. To evaluate effects of weight loss treatment on clinic/laboratory inflammation metabolic profile, reactive oxygen species (ROS) body composition patients NCDs. Design: A 6-week open, pilot prospective clinical trial. Setting: The study included 72 adult COVID influenza type 2 diabetes (T2D), hypertension, NASH....
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Abstract Background: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) investigate demographic factors comorbidities associated with all-cause mortality by aggregating utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) for 2014-2019 years period. Methods: used Kaplan-Meier log-rank test calculate failure function differences in survival age, sex, ethnicity, Type 1 2 DM. Cox proportional hazards...
Abstract Background: We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) investigate demographic factors comorbidities associated with all-cause mortality by aggregating utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) for 2014-2019 years period. Methods: used Kaplan-Meier log-rank test calculate failure function differences in survival age, sex, ethnicity, Type 1 2 DM. Cox proportional hazards...
ABSTRACT Background COVID and Influenza with non-communicable chronic diseases (NCDs) complicate the diagnosis, treatment, prognosis, increase mortality rate. The aim: to evaluate effects of fast weight loss on clinic laboratory inflammation profile, metabolic reactive oxygen species (ROS) body composition in patients comorbidity NCDs. Methods A 6-week open, pilot prospective clinical trial including 62 adult (n=27) influenza (n=35) T2D, hypertension, NASH. Overweight 33 (53.2%) BMI...