A5040403654- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Cancer Immunotherapy and Biomarkers
- Cancer Treatment and Pharmacology
- Ferroptosis and cancer prognosis
- Colorectal Cancer Surgical Treatments
- Cancer Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- BRCA gene mutations in cancer
- Advanced Breast Cancer Therapies
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Inflammasome and immune disorders
- Chemotherapy-related skin toxicity
- Thyroid and Parathyroid Surgery
- Epigenetics and DNA Methylation
- Lung Cancer Research Studies
- Digital Radiography and Breast Imaging
- Brain Metastases and Treatment
- Cancer Genomics and Diagnostics
- PARP inhibition in cancer therapy
- Extracellular vesicles in disease
- AI in cancer detection
Southwest Hospital
2022-2025
Army Medical University
2022-2025
Minimal access breast surgery (MABS) has been used in cancer management. However, long-term prognostic data associated with MABS vs conventional (CBS) are lacking.
Abstract Background Our previous work indicated that the addition of lobaplatin to combined therapy with taxane and anthracycline can improve pathological complete response rate neoadjuvant for triple-negative breast cancer (TNBC) lengthen long-term survival significantly, but therapeutic markers this regimen are unclear. Methods Eighty-three patients who met inclusion criteria were included in post hoc analysis. We analyzed association between platelet-to-lymphocyte ratio (PLR)...
Early diagnosis of breast cancer has always been a difficult clinical challenge. We developed deep-learning model EDL-BC to discriminate early with ultrasound (US) benign findings. This study aimed investigate how the could help radiologists improve detection rate while reducing misdiagnosis.In this retrospective, multicentre cohort study, we an ensemble deep learning called based on convolutional neural networks. The was trained and internally validated B-mode color Doppler US image 7955...
Abstract Background Previous studies have shown that the addition of platinum to neoadjuvant chemotherapy (NAC) improved outcomes for patients with triple-negative breast cancer (TNBC). However, no assessed efficacy and safety combination taxane lobaplatin. In this study, we conducted a randomized controlled phase II clinical study compare combined lobaplatin or anthracycline. Methods We randomly allocated stage I–III TNBC into Arm A B. received six cycles (TL). B anthracycline...
The approach of neoadjuvant therapy for breast cancer, which involves administering systemic treatment prior to primary surgery, has undergone substantial advancements in recent decades. This strategy is intended reduce tumor size, thereby enabling less invasive surgical procedures and enhancing patient outcomes. study presents a comprehensive bibliometric analysis research trends cancer from 2009 2024. Using data extracted the Web Science Core Collection, total 3,674 articles were analyzed...
Anlotinib is a new type of tyrosine kinase inhibitor that targets vascular endothelial growth factor receptors 1/2/3, platelet-derived α/β, and fibroblast 1-4 c-Kit, with broad spectrum inhibitory effects on tumor angiogenesis growth. It has been proven effective in HER2-negative metastatic breast cancer, but its efficacy early-stage triple-negative cancer (TNBC) unknown. This phase 2 study aims to evaluate the safety adding anlotinib neoadjuvant chemotherapy patients TNBC.
e18069 Background: Open thyroidectomy (TT) with modified radical neck dissection (MRND) is used for papillary thyroid carcinoma (PTC) clinical lateral node metastasis (cN1b). robotic surgery TT MRND being carried out and some studies have confirmed its efficacy. However, such are limited by indicators samples. The study aimed to compare open in patients cN1b PTC efficacy, safety, oncological outcomes quality of life. Methods: In this retrospective cohort study, 2027 receiving between January...
e12597 Background: Subcutaneous gland resection of the breast combined with primary prosthesis reconstruction is mostly used for early cancer (EBC) patients. In this study, we compared long-term quality life (QOL) patients who underwent these procedures in a minimally invasive or open approach. Methods: The baseline data EBC subcutaneous approach from 2008 to 2020 were retrospectively analyzed. receiving surgery regarded as group, and group. BREAST-Q questionnaires evaluate patients’...
594 Background: Previously, we showed that addition of lobaplatin (L) to taxane (T) combined with anthracycline (E) could improve the pathological complete response (pCR) rate neoadjuvant therapy for triple-negative breast cancer (TNBC) and lengthen long-term survival significantly, but therapeutic markers this regimen are not known. We investigated if platelet/lymphocyte ratio (PLR) neutrophil/lymphocyte (NLR) be used predict efficacy TEL regimen. Methods: Eighty-three patients TNBC (stage...
593 Background: Previously, we showed that addition of lobaplatin (L) to taxane combined with anthracycline could improve the pathologic complete response (pCR) rate and lengthen survival significantly if employed as neoadjuvant therapy in patients triple-negative breast cancer (TNBC). We evaluated efficacy safety chemotherapy (T) or (E) for TNBC. Methods: Ninety-five TNBC (stage I–III) who had not undergone any type treatment were divided randomly into two groups: TL (docetaxel at 75 mg/m 2...
Breast cancer is the most common malignancy in women, and there evidence for dual role of cell pyroptosis tumor development. However, little known about relationship between breast its prognostic value. We aimed to construct a model using cell-pyroptosis-related genes provide innovative insights into prognosis treatment cancer. screened candidate public databases identified 10 signature with random forest method. Finally, nomogram predicting 1-, 3-, 5-year survival probabilities was...