Xiaofei Hu

ORCID: 0000-0001-5376-2779
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Functional Brain Connectivity Studies
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Protease and Inhibitor Mechanisms
  • Soil Carbon and Nitrogen Dynamics
  • Advanced MRI Techniques and Applications
  • COVID-19 diagnosis using AI
  • Dermatology and Skin Diseases
  • COVID-19 Clinical Research Studies
  • MRI in cancer diagnosis
  • Cerebrovascular and Carotid Artery Diseases
  • Advanced Neuroimaging Techniques and Applications
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatic and Hepatic Oncology Research
  • Allergic Rhinitis and Sensitization
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Advanced X-ray and CT Imaging
  • Asthma and respiratory diseases
  • Visual perception and processing mechanisms
  • Neurological Disease Mechanisms and Treatments
  • Liver Disease Diagnosis and Treatment
  • Mental Health Research Topics
  • Land Use and Ecosystem Services
  • Color perception and design

Army Medical University
2016-2025

Southwest Hospital
2016-2025

The Affiliated Yongchuan Hospital of Chongqing Medical University
2022-2025

Zaozhuang University
2025

AbbVie (United States)
2020-2024

Capital Medical University
2024

Nanchang University
2009-2024

Huangshi Central Hospital
2024

Wenzhou Medical University
2014-2024

Ministry of Water Resources of the People's Republic of China
2024

Atopic dermatitis (AD) is a chronic, recurrent, inflammatory skin disease with an unmet need for treatments that provide rapid and high levels of clearance itch improvement.

10.1001/jamadermatol.2021.3023 article EN cc-by-nc-nd JAMA Dermatology 2021-08-04

Abstract Background Metabolic syndrome (MetS), a worldwide public health problem, affects human and quality of life in dramatic manner. A growing evidence base suggests that MetS is strongly associated with levels systemic immune inflammation. The present study aimed to investigate the possible relationship between immune-inflammation index (SII), novel inflammatory marker, provide data support for effective prevention by reducing response. Methods We included adult participants complete SII...

10.1186/s12967-023-04491-y article EN cc-by Journal of Translational Medicine 2023-10-04

The occurrence and development of Parkinson's disease (PD) have been demonstrated to be related gut dysbiosis, however, the impact fecal microbiota transplantation (FMT) on engraftment in PD patients is uncertain. We performed a randomized, placebo-controlled trial at Department Neurology, Army Medical University Southwest Hospital China (ChiCTR1900021405) from February 2019 December 2019. Fifty-six participants with mild moderate (Hoehn-Yahr stage 1–3) were randomly assigned FMT placebo...

10.1080/19490976.2023.2284247 article EN cc-by Gut Microbes 2023-12-06

Systemic atopic dermatitis treatments that have acceptable safety are needed.To evaluate the of oral Janus kinase inhibitor upadacitinib in combination with topical corticosteroids (TCSs) for treatment dermatitis.In this phase 3, double-blind study (Rising Up), Japanese patients (12-75 years) moderate-to-severe were randomized a 1:1:1 ratio to receive 15 mg + TCS, 30 or placebo TCS (rerandomized 1:1 either at week 16). Adverse events and laboratory data assessed safety.In 272 treated...

10.1016/j.jdin.2021.11.001 article EN cc-by-nc-nd JAAD International 2021-12-20

Approximately 60% of patients with atopic dermatitis have involvement the hands adding to burden disease.This analysis aims evaluate effect upadacitinib monotherapy on hand eczema in moderate-to-severe AD over 16 weeks Measure Up 1 and 2 studies.Data from (ages 12-75) randomized 1:1:1 receive 15 mg, 30 or placebo once daily studies were analysed for impact assessed using Hand Eczema Severity Index (HECSI). The percent change baseline HECSI score was a prespecified additional endpoint at all...

10.1111/jdv.19194 article EN cc-by-nc Journal of the European Academy of Dermatology and Venereology 2023-05-15

A full evaluation of health conditions is necessary for the effective implementation public interventions. However, terms to address intermediate state between and disease are lacking, leading overlook this thus increasing risks developing disease. cross-sectional survey 1,473 randomly recruited Chinese Han adults both sexes living in central region China. The criteria diagnosis subhealth was defined as presence ≥ 1 following abnormalities: body mass index 25 kg/m2 or waist circumference 102...

10.1186/1471-2458-13-446 article EN cc-by BMC Public Health 2013-05-04

Amyotrophic lateral sclerosis (ALS) is a rare degenerative disorder characterized by loss of upper and lower motor neurons. Neuroimaging has provided noticeable evidence that ALS complex disease, shown anatomical functional lesions extend beyond precentral cortices corticospinal tracts, to include the corpus callosum; frontal, sensory, premotor cortices; thalamus; midbrain. The aim this study investigate graph theory-based network abnormalities at voxel-wise level in patients on whole brain...

10.3389/fnins.2016.00204 article EN cc-by Frontiers in Neuroscience 2016-05-10

Up to 40%-65% of patients with perihilar cholangiocarcinoma (PHC) rapidly progress early recurrence (ER) even after curative resection. Quantification ER risk is difficult and a reliable prognostic prediction tool absent. We developed validated multilevel model, integrating clinicopathology, molecular pathology radiology, especially radiomics coupled machine-learning algorithms, predict the resection in PHC.In total, 274 who underwent contrast-enhanced CT (CECT) at 2 institutions were...

10.1111/liv.14763 article EN Liver International 2020-12-11

Parkinson's disease (PD) is a progressive neurodegenerative characterized by both motor and non-motor symptoms. A convergent pathophysiological hallmark of PD an early selective vulnerability within the basal ganglia circuit. However, causal interactions between atrophy structural network alterations in remain unaddressed. Here, we adopted voxel-based morphometry method to measure gray matter (GM) volume for each participant (n = 84 patients n 70 matched healthy controls). Patients were...

10.1002/hbm.25715 article EN Human Brain Mapping 2021-11-18

This study aimed to investigate the impact of tibial anatomical structure, age, sex, average weekly exercise time during adolescence (AWETA), and BMI on risk stress fractures (SF) develop a predictive model using logistic regression. We retrospectively analyzed 748 patients presenting with calf pain at our hospital from January 1, 2018, August 31, 2023. After applying inclusion exclusion criteria, 493 were categorized into SF group (295 cases) control (198 cases). Detailed patient...

10.1016/j.ejrad.2025.111932 article EN cc-by-nc European Journal of Radiology 2025-01-19

Abstract The importance of nonmotor symptoms in understanding the pathogenesis heterogeneity Parkinson’s disease has been highlighted. However, validation specific brain network biomarkers symptom subtypes is currently lacking. By performing a new approach to compute functional connectivity with structural prior using magnetic resonance imaging, present study computed both and fusional features disease, one characterized by cognitive impairment late onset other depression early onset....

10.1093/cercor/bhaf002 article EN Cerebral Cortex 2025-01-22

The approach of neoadjuvant therapy for breast cancer, which involves administering systemic treatment prior to primary surgery, has undergone substantial advancements in recent decades. This strategy is intended reduce tumor size, thereby enabling less invasive surgical procedures and enhancing patient outcomes. study presents a comprehensive bibliometric analysis research trends cancer from 2009 2024. Using data extracted the Web Science Core Collection, total 3,674 articles were analyzed...

10.1080/21645515.2025.2460272 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2025-02-04

Abstract In this study, a series of temperature-controlled terahertz (THz) wave modulators based on combination magnetron-sputtered strontium titanate (STO) thin films and metasurfaces have been proposed. As the sputtering temperature increased from 25 to 600 °C, STO exhibited an evolution amorphous polycrystalline states thus different dielectric responses were observed in THz band. Differences performance the
THz such as differences variation trends amplitude frequency resonance...

10.1088/1402-4896/adb3d9 article EN Physica Scripta 2025-02-07

Three nomogram models combining apparent diffusion coefficient and clinicopathologic features showed good performance in predicting status of pretreatment axillary lymph nodes, nonsentinel the nodes after neoadjuvant chemotherapy treatment patients with breast cancer.

10.1148/rycan.240202 article EN Radiology Imaging Cancer 2025-03-01
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