A5061785886- Folate and B Vitamins Research
- Pregnancy and preeclampsia studies
- MicroRNA in disease regulation
- Acute Ischemic Stroke Management
- Abdominal vascular conditions and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer-related molecular mechanisms research
- Apelin-related biomedical research
- Cerebrovascular and Carotid Artery Diseases
- GDF15 and Related Biomarkers
- Liver Disease and Transplantation
- Gastrointestinal Bleeding Diagnosis and Treatment
- Berberine and alkaloids research
- RNA modifications and cancer
- Infectious Encephalopathies and Encephalitis
- Chronic Disease Management Strategies
- Ferroptosis and cancer prognosis
- Transcranial Magnetic Stimulation Studies
- Chronic Kidney Disease and Diabetes
- Sulfur Compounds in Biology
- Optical Imaging and Spectroscopy Techniques
- Esophageal and GI Pathology
- Diagnosis and Treatment of Venous Diseases
- Drug Transport and Resistance Mechanisms
- Flavonoids in Medical Research
China Foreign Affairs University
2025
Xiang Yang No.1 People's Hospital
2024
Hubei University
2024
Qingdao University
2022-2023
Shanxi Academy of Medical Sciences
2018-2023
Taian City Central Hospital
2020-2023
Shandong University
2020-2021
Shandong Provincial QianFoShan Hospital
2020-2021
Nanjing Drum Tower Hospital
2020
Affiliated Hospital of Shaanxi University of Chinese Medicine
2020
ABSTRACT This study investigated the effects of combining repetitive transcranial magnetic stimulation (rTMS) with bilateral arm training (BAT) on effective brain connectivity in chronic stroke patients using functional near‐infrared spectroscopy. Fifteen post‐stroke and fifteen healthy individuals were enrolled. Coupling function analysis was performed to evaluate inflow, outflow, dominant information flow (DIF) during standalone BAT combined rTMS‐BAT therapy. Significant task‐related...
Background: Diabetic nephropathy (DN) is the leading cause of morbidity and mortality in diabetic patients. Tetrandrine (Tet), a bisbenzylisoquinoline alkaloid isolated from roots Stephania tetrandra, possesses anti-oxidative, anti-hypertensive, anti-inflammatory capacities. In this study, maintenance role Tet DN was evaluated streptozotocin (STZ)-induced rats. Methods: vitro rats were divided into five groups (n=10): control group, model Tet-treatment group (5, 15, 30 mg/kg). damage...
Major criticism of randomized clinical trials comparing carotid artery stenting (CAS) and endarterectomy (CEA) focused on the incomplete learning curve interventionists inadequate outdated technology employed, which might have contributed to high stroke death rates in CAS arm. The effect related technical expertise patient selection strongly influences results CAS. Due devastating potential complications when compared with other endovascular minimally invasive procedures, requires a more...
Emergency endoscopy is recommended for patients with acute esophageal variceal bleeding (EVB) and their prognosis has improved markedly over past decades due to the increased specialization of endoscopic practice. The study aimed compare outcomes following emergency injection sclerotherapy (EIS) ligation (EVL) in cirrhotic EVB.Cirrhotic EVB who underwent were retrospectively enrolled from 2013 2020 across 34 university hospitals 30 cities. primary outcome was incidence 5-day rebleeding after...
Background: Endoscopy plays an important role in the management of acute variceal bleeding (AVB) patients with cirrhosis. This study aimed at determining optimal endoscopy timing for cirrhotic AVB. Methods: Patients cirrhosis AVB across 34 university hospitals 30 cities from February 2013 to May 2020 who underwent within 24 hours were included this study. divided into urgent group (endoscopy <6 h after admission) and early 6–24 admission). Multivariable analysis was performed identify...
This study aims to research the factors influencing hospitalization costs of patients with type 2 diabetes, so as provide some references for reducing their economic burden. Based on Hospital Information System a 3A grade hospital in China, we analyzed 2970 cases diabetes during 2005-2012. Both number inpatients and had increased period. Using multiple linear regression analysis, found that Urban Employee Basic Medical Insurance higher than those New Rural Cooperative Scheme. We also be male...
Objective This study aimed to explore the expression and biological functions of SIRT3 in colorectal cancer cells (HCT-116), impacts sulforaphane on ferroptosis HCT-116 involvement SIRT3/AMPK/mTOR axis those effects. Methods SIRT3-overexpressing (OE) SIRT3-knockout (KO) cell lines were treated with different concentrations sulforaphane, RSL-3, IKE. Cell viability, intracellular ROS, MDA, iron levels, as well mRNA protein expressions target genes measured. Results was increased by inducers...
Hypertension is a common cause of kidney injury and renal damage occurs earlier more serious in patients with hypertension hyperhomocysteinaemia (HHCY). Folic acid (FA) widely used to ameliorate the organ caused by HHCY. However, effective dose FA remains controversial certain studies have suggested that increases risk cancer. Therefore, it necessary identify safe, drug. Resveratrol (RSV) natural polyphenol antioxidant. present study explored effects RSV on spontaneously hypertensive rats...
This study was to develop a CO breath test for RBC lifespan estimation of small animals. The ribavirin induced hemolysis rabbit models were placed individually in closed rebreath cage and air samples collected measurement concentration. calculated from accumulated CO, blood volume, hemoglobin concentration data. determined the same animals with standard biotin-labeling method. data obtained by method control (CON, 49.0 ± 5.9 d) rabbits, rabbits given 10 mg/kg·d(-1) (RIB10, 31.0 4.0 d), 20...
To evaluate whether lowering plasma homocysteine (Hcy) levels at different doses of folic acid (FA) could reduce cardiac fibrosis and diastolic dysfunction in spontaneously hypertensive rats (SHRs) with hyperhomocysteinemia (Hhcy) investigate the possible mechanism action.We randomly divided 32 male SHRs into control, Hhcy, Hhcy + low-dose FA (LFA), high-dose (HFA) groups. Echocardiography Masson staining tissue were used to assess function fibrosis. Blood pressure (BP) Hcy measured during...
Hyperhomocysteinemia (HHcy) plays a synergistic role with hypertension in vascular injury; however, the relationship between HHcy and renal injury remains unclear. Here, we sought to evaluate context of elucidate mechanism action underlying this relationship.Wistar Kyoto (WKY) rats spontaneously hypertensive (SHR) were randomized into WKY, WKY + HHcy, SHR, SHR groups. Blood pressure, plasma homocysteine, serum malondialdehyde (MDA), superoxide dismutase (SOD), urinary albumin creatinine...
Objective. Periodontal disease has been associated with pregnancy complications including preeclampsia. This bioinformatic study is aimed at investigating the possible role of circulating microRNAs (miRNAs) as mediators association between maternal periodontal and Methods. Peripheral blood miRNA profiles periodontitis controls were sought from Gene Expression Omnibus (GEO), differential expression analysis was performed. Experimentally validated miRNAs preeclampsia determined Human MicroRNA...
Hemolytic anemia is a major side effect of ribavirin antiviral treatment for chronic hepatitis C. Ribavirin dose reduction may compromise the response and erythropoietin can take several weeks to alleviate anemia. The purpose present study was screen potentially protective drugs against ribavirin-induced hemolytic in rabbit model, using our modified CO breath test measuring erythrocyte (RBC) lifespan, gold standard diagnostic index hemolysis. Fifteen rabbits were divided randomly into five...
Objective: The aim of this double-masked, placebo-controlled trial was to confirm the anaesthetic effect EMLA cream compared with placebo when used for sharp debridement venous leg ulcers and test its feasibility respect usual procedure. Methods: One hundred ten patients were randomised or treatment 30-45 min. Pain from evaluated by patient on a 100 mm visual analogue scale (VAS) physician verbal scale. Results: median VAS scores 16.5 52 in EMLA- placebo-treated patients, respectively...
The relationship between thyroid dysfunction and gallstone disease (GSD) has been examined by some observational studies. However, evidence about the function GSD among euthyroid subjects was scarce. aim of this study to investigate association presence in a large-sample subjects. A total 5476 who underwent health checkup were included. diagnosed hepatic ultrasonography. Conventional risk factors for assessed as well serum levels TSH, TT3, TT4 Log-transformed TT3/TT4 ratio. 4958 finally...
Coronary artery disease (CAD) is the most common aging-related in adults. We used bioinformatics analysis to study genes associated with aging patients CAD. The microarray data of GSE12288 dataset were downloaded from Gene Expression Omnibus database obtain 934 CAD-associated differentially expressed genes. By overlaying them Aging Atlas database, 33 (DEARGs) identified. Ontology and Kyoto Encyclopedia Genes Genomes enrichment analyses revealed that DEARGs mainly enriched cell adhesion...