Karolina A. Pawłowska

ORCID: 0000-0003-2024-7441
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About
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Research Areas
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Natural product bioactivities and synthesis
  • Plant-Derived Bioactive Compounds
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Dermatology and Skin Diseases
  • Phytochemicals and Antioxidant Activities
  • Inflammasome and immune disorders
  • Complementary and Alternative Medicine Studies
  • Nigella sativa pharmacological applications
  • Tea Polyphenols and Effects
  • Plant and animal studies
  • Plant-derived Lignans Synthesis and Bioactivity
  • Lichen and fungal ecology
  • African Botany and Ecology Studies
  • Natural Antidiabetic Agents Studies
  • Heavy Metals in Plants
  • Phytoestrogen effects and research
  • Phytochemistry and Bioactive Compounds
  • Pharmacological Effects of Natural Compounds
  • Adipokines, Inflammation, and Metabolic Diseases
  • Pharmacological Effects of Medicinal Plants
  • Natural Compound Pharmacology Studies
  • Synthesis of Organic Compounds
  • Tryptophan and brain disorders

Medical University of Warsaw
2017-2024

The isolation of phenolics from aerial parts Corispermum marschallii yielded a total 13 compounds including nine previously undescribed patuletin and spinacetin glycosides. These were identified as 3- O-β-d-galactopyranosyl-7- O-β-d-glucopyranoside (1), (2), O-(6″- O-β-d-glucopyranosyl)-β-d-galactopyranoside (3), O-α-l-arabinopyranosyl)-β-d-galactopyranoside (4), O-(2″- O-(5‴- O-α-l-arabinopyranosyl)-β-d-apiofuranosyl)-β-d-galactopyranoside (5), O-β-d-apiofuranosyl)-β-d-galactopyranoside...

10.1021/acs.jnatprod.8b00152 article EN Journal of Natural Products 2018-08-15

Phaseaoli pericarpium (bean pods) is a pharmacopeial plant material traditionally used as diuretic and antidiabetic agents. Diuretic activity of pod extracts was reported first in 1608. Since then Phaseoli tea figures many textbooks medicinal by patients. Despite the traditional use from Phaseolium vulgaris pericarp, limited information available on bioactivity, chemical composition, bioavailability such preparations. The following study aimed to investigate phytochemical vitro permeability...

10.1016/j.jep.2021.114053 article EN cc-by-nc-nd Journal of Ethnopharmacology 2021-03-20

Porophyllum ruderale subsp. is a food product used for seasoning in Central and Southern America. The present research aimed to investigate the chemical composition of an extract prepared from aerial parts P. using UHPLC-DAD-MS/MS, isolate identify major natural products extract, furtherly their anti-inflammatory activity vitro. Twenty-five compounds were detected characterized UV-Vis MS data. All quantified. Ten phenolics isolated identified by NMR. One previously undescribed was...

10.1016/j.foodchem.2021.131116 article EN cc-by-nc-nd Food Chemistry 2021-09-14

Lythrum salicaria herb (LSH) was applied in diarrhea therapy since ancient times. Despite empirically referenced therapeutic effects, the bioactivity mechanisms and chemical constituents responsible for pharmacological activity remain not fully resolved. Taking into consideration historical use of LSH treatment humans farm animals, aim study to examine vitro influence its C-glycosylic ellagitannins on processes associated with maintaining intestinal epithelium integrity enteropathogenic...

10.1021/acs.jnatprod.0c00776 article EN cc-by Journal of Natural Products 2020-12-03

Abstract The widely accepted strategy to justify the use of medicinal plant extracts in diseases with inflammatory background is their examination on vitro models using immune cells. It also a key initial step research for active principles, which could be then isolated and tested more advanced models, becoming new pharmacologically lead molecules. crucial aspect has not been so far addressed this context, presence pyrogens preparations. aim study was interference evaluation...

10.1038/s41598-020-79579-2 article EN cc-by Scientific Reports 2021-01-12

Traditionally-used medical plants, such as silver birch, might be useful in supporting antimicrobial therapy and the prevention of urinary tract infections (UTI) [1]. Their constituents, metabolized excreted urine, act therapeutically on infected or even get activated by uropathogens’ own enzymes [2]. Presented research is focused describing urine metabolites birch leaves infusion.

10.1055/s-0041-1736784 article EN Planta Medica 2021-12-01

Tiliae flos is a pharmacopeial plant material used in the form of infusions threatmant feverish colds and upper respiratory tracts irritations. Previous studies have shown that lime flowers contain significant amounts flavonoids, mucilage essential olis [1]. Recent research revealed also procyanidins from which only few compounds were identified [2]. One kilogram dried was extracted with acetone:methanol:water (3:1:1) to be next separated by liquid-liquid extraction. Ten flavan-3-ol...

10.1055/s-0037-1608129 article EN Planta Medica International Open 2017-10-01

Corispermum marshallii Steven is an herbaceous annual plant material belonging to the Amaranthaceae family. In Poland this a domesticated species occurring in open, gravelly or sand habitats. literature there are no studies considering polyphenolic composition of aerial parts any species. Available research shows, that materials genus contain ecdysteroids and some isoquinoline alkaloids including salsoline salsolidine.

10.1055/s-0037-1608243 article EN Planta Medica International Open 2017-10-01

Silver birch leaves (Betula pendula Roth/Betula pubescens Ehrh.) is a plant material used in the treatment of urinary tract disorders as diurectic agent [1]. It administered orally infusion.

10.1055/s-0042-1759281 article EN Planta Medica 2022-12-01

Birch leaves (Betula pendula Roth, Betula pubescens Ehrh.) is a plant material traditionally used in gout, rheumatism, arthritis, and urinary tract conditions. The main constituents of the birch leaf water infusion are flavonoids, phenolic acids, glycosides. In previous reports, diuretic activity flavonoid-free extract was confirmed [1]. most abundant non-flavonoid constituent 3-hydroxy-1-(4-hydroxyphenyl)-propan-1-one 3-O-β-D-glucoside (3,4′-DHPPG) [2]. aim research to isolate this compound...

10.1055/s-0042-1759084 article EN Planta Medica 2022-12-01
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