A5013167076- Zebrafish Biomedical Research Applications
- Microplastics and Plastic Pollution
- Nanoparticles: synthesis and applications
- Animal Behavior and Reproduction
- Fish Ecology and Management Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Trace Elements in Health
- Neuroscience and Neuropharmacology Research
- Primate Behavior and Ecology
- Marine Biology and Environmental Chemistry
- Neuroendocrine regulation and behavior
- COVID-19 and Mental Health
- Apelin-related biomedical research
- Stress Responses and Cortisol
- Pharmacological Effects and Toxicity Studies
- Phytochemical and Pharmacological Studies
- Sleep and Wakefulness Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Food Science and Nutritional Studies
- Circadian rhythm and melatonin
- Heavy Metal Exposure and Toxicity
- Nuclear Receptors and Signaling
- Adipose Tissue and Metabolism
- Birth, Development, and Health
Alexandru Ioan Cuza University
2019-2025
Grigore T. Popa University of Medicine and Pharmacy
2020
Academy of Romanian Scientists
2020
"Ion Ionescu de la Brad" Iasi University of Life Sciences
2020
Romanian Academy
2020
University of Agricultural Sciences, Dharwad
2020
Luminit (United States)
2020
Lately, the interest in researching microplastics Black Sea has increased, highlighting areas of accumulation which amounts are alarming, such as seafood consumed by population. The special characteristics terms currents and wave dynamics that create opportunities for hotspot points, context large rivers discharge contains pollutants new sources contamination. This article offers a literature-based profile on plastic pollution Sea—pollution originates rivers, transportation, other economic...
The effects of exposure to environmental pollutants on neurological processes are increasing concern due their potential induce oxidative stress and neurotoxicity. Considering that many industries currently using different types plastics as raw materials, packaging, or distribution pipes, microplastics (MPs) have become one the biggest threats environment human health. These consequences led need raise awareness regarding MPs negative implication in neuropsychiatric pathologies, such...
Zebrafish have the ability, to a certain extent, distinguish between different types of stimuli, including distinguishing videos conspecifics and non-conspecifics, skill known as stimulus discrimination. In this study, we investigated effects oxytocin on ability in albino non-albino zebrafish models, focusing correlations albinism, sensory deficiencies, socio-emotional behaviors. Our hypothesis is based premise that influences behaviors zebrafish, with varying depending phenotype (albino vs....
Zinc contamination in aquatic environments has become a growing concern due to its potential bioaccumulate and induce neurotoxic effects organisms. As an essential trace element, zinc plays crucial role various physiological processes, but excessive exposure can disrupt the gut–brain axis, leading cognitive behavioral impairments. Recent studies have suggested that probiotics may offer protective against environmental neurotoxins by modulating gut microbiota associated neurological...
Microplastic pollution represents an emerging problem of great interest in the public domain last decade; addition, it overlaps with another delicate problem—pollution pharmaceutical products that can have negative effects on environment and people, even small amounts. The main purpose this study was to assess biochemical behavioral exposure adult zebrafish (Danio rerio) polyethylene (PE), polypropylene (PP) valproic acid (VPA), respectively their mixtures—possible situations natural aquatic...
Microplastic pollution represents an emerging problem of great interest in the public domain last decade; addition, it overlaps with another delicate - pharmaceutical products that can have negative effects on environment and people, even small amounts. The main purpose this study was to assess biochemical behavioral exposure adult zebrafish (Danio rerio) polyethylene (PE), polypropylene (PP) valproic acid (VPA), respectively their mixtures possible situations natural aquatic environments....
Parkinson's disease (PD) is an enigmatic neurodegenerative disorder that currently the subject of extensive research approaches aiming at deepening understanding its etiopathophysiology. Recent data suggest distinct compounds used either as anticonvulsants or agents usually dopaminergic agonists supplements consisting live active lactic acid bacteria strains might alleviate and improve PD-related phenotypes. This why we aimed to elucidate how administration rotenone (ROT) disrupts...
Considering the awareness regarding oxidative stress status implication in most of actual neuropsychiatric disorders and also ever increasing importance zebrafish studies this context, present paper we were interested general biological relevance replicating some manifestations zebrafish, by focusing on autism spectrum disorder, schizophrenia Alzheimer's disease.Also considering increased sleep-related pathology existence intriguing sleep as well correlations between digestive-related such...
Zebrafish (Danio rerio) are currently used for various biomedical and environmental studies.Due to the comprehensive ethological genetical description, but also due a significant similarity humans, zebrafish successfully in modelling some traits associated with human pathology (both psychiatric others) determining effects of factors on behaviour highly conserved molecular processes.Due fact that chronic exposure stress is major problem contemporary society, any description phenomenon finding...
Polymeric materials became of crucial interest in the research area over recent years due to worldwide production increase these not always being followed by knowledge their possible detrimental effects. Therefore, present study we analyzed different effects polymeric at various exposure times. Our results focused on some general terms anxiety and swimming performance 120h multiple repeated doses both Polyethylene Polypropylene microplastics. showed an anxiogenic potential, while exhibited...
Schizophrenia spectrum disorders are one of the most debilitating as it severely impacts day-to-day life individual. Therefore, during recent years, using zebrafish to model schizophrenia has become a reliable and popular choice due similarities in terms genetics brain structure that human brain. Often times, approach is use ketamine order induce positive symptoms this disorder zebrafish. However, method may be lacking since only mimics symptoms, represented by delusions, hallucinations,...
Zebrafish has a complex social behavior and little is known about the role of sexual preference their environmental interactions. In this study we investigated potential influence colors shoaling preferences zebrafish male female populations, with focus on visual communication. Males females were kept for 7 days in gender-isolated tanks, specific habitat color each group: green males red females. After pre-test period, all animals separated 8 noninvasive behavioral tests conducted T-maze,...
Zebrafish (Danio rerio) is considered an experimental model organism with numerous applications in different fields. The mechanisms underlying social and reproductive preferences are complex. Most of the literature on conspecific interactions focus chemical communication mediated by scattered signals aquatic medium. aim this research was to evaluate behavioral responses induced tested animals artificial stimuli. We used 20 sexually mature individuals that underwent several non-invasive tests...
Modern world is relying more and on the use of plastics in order to conduct our daily tasks going from simple lid that covers morning coffee large scale packaging buildings.But how does so much plastic influence human's normal growth development or importantly, it affect brain functions?For purpose this paper giving a little literature insight over toxic effects micro-/nanoplastics we chose approach multidisciplinary point view with focus zebrafish as animal models; ranging microplastics...
Background: People choosing to follow a university degree are exposed different degrees of stress and anxiety that might be higher lower depending on the level study, field interest even age sex.It is well-known fact social isolation with little no contact other people has an impact mental health any individual.Objective:The aim this study was evaluate its gastrointestinal as consequence lockdown caused by Covid-19.Method: A cross-sectional conducted using single questionnaire representing...
When it comes to pollutants in the aquatic environment, there is a wide variety of products, from fibers and plastics food medicinal compounds their by-products. Pollutants have been an area interest for decades are becoming more popular with each passing year, whether presence effects studied separately by class or combination. Among all, polymeric materials center attention, environment has long established studies on harmful effects. Improper disposal pharmaceutical just one many ways...
While we previously described helplessness learned model and chronic mild stress (CMS) model, in the present mini-review continue our interest describing main animal models of depression (e.g.we here forced swim test tail suspension test), their neuropsychiatric relevance, as well way there are correlated with some related metabolic manifestations.