A5039504054- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Hepatitis B Virus Studies
- Esophageal and GI Pathology
- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Liver Diseases and Immunity
- Pediatric Hepatobiliary Diseases and Treatments
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal Tumor Research and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Biliary and Gastrointestinal Fistulas
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2016-2025
Grigore T. Popa University of Medicine and Pharmacy
2016-2025
Romanian Academy
2013-2024
Academy of Romanian Scientists
2024
Emergency University
2020
Alexandru Ioan Cuza University
2020
Clinica de Pneumologie Iaşi
2010-2018
Corporació Sanitària Parc Taulí
2015
Vall d'Hebron Hospital Universitari
2014
Centro Hospitalar de Trás os Montes e Alto Douro
2014
Oesophageal acid clearing has been measured by counting the number of swallows needed to raise lower oesophageal pH from 1.5 5.0 after instilling 15 ml 0.1 N hydrochloric acid. Normal subjects all had a result less than 12, as did asymptomatic patients with hiatal hernias. Patients symptomatic gastrooesophageal reflux tended have abnormal clearance, those motility disorders. Acid clearance correlated well mean duration spontaneous episodes during 15-hour continuous recordings pH. Abnormal...
Gastro-oesophageal sphincter pressure and intraoesophageal pH has been studied in 25 chronic smokers who complained of heartburn. Smoking a cigarette invariably caused fall pressure, measurements showed an increased tendency for reflux to occur while smoking. When lower oesophageal was measured overnight one-third all episodes occurred the patients were smoking, seen during smoking two-thirds cigarettes consumed. It is concluded that common reversible cause gastro-oesophageal reflux.
A series of tests, including gastro-oesophageal sphincter pressure measurement, short-term pH and 15-hour overnight oesophageal recording were applied to 42 normal subjects 214 patients with typical reflux symptoms. The results compared by multivariate discriminant analysis. Sphincter measurements misclassified 32%, stressed provocative manoeuvres 14-5%, the best single discriminator from study was time below 5, which 13%. However, a combination number episodes in 15 hours their mean...
Continuous oesophageal pH measurements have been used to assess the influence of posture (lying, sitting, bed-up) on gastro-oesophageal reflux. The percentage time during which was below 5 and number reflux episodes significantly reduced when patients were in bed-up position than sitting or lying. There no significant difference lying positions compared. results suggest that by adopting (elevation head end bed with blocks 28 cm), patient will a symptomatic benefit, frequency is decreased,...
In 30 patients with gastrooesophageal reflux, intravenous metoclopramide (Maxolon) has been shown to increase the sphincter pressure. The rise is dose-related until a maximum pressure, proportional resting tone, reached. effect reversed by atropine. Peristaltic waves are increased in pressure metoclopramide.In 18 reflux diminished frequency of episodes and rate at which oesophagus emptied itself an acid load.
Background/Objectives: Esophageal varices (EVs) represent an important portal hypertension complication in patients with compensated advanced chronic liver disease (cACLD). Although upper gastrointestinal endoscopy is currently the gold standard for EV diagnosis, recent guidelines recommend non-invasive approaches to assess risk cACLD reduce unnecessary endoscopies. Our study aims evaluate spleen stiffness measurement (SSM) using 2D shear-wave elastography (2D-SWE) as a predictor of presence...
<b>Stanciu, C. and Bennett, J. R. (1974).</b><i>Thorax</i>, <b>29</b>, 459-462. <b>Upper oesophageal sphincter yield pressure in normal subjects patients with gastro-oesophageal reflux.</b> Upper was measured 26 69 reflux, using a system of continuously perfused catheters. There no significant difference between the two groups. Perfusion oesophagus hydrochloric acid produced change pressure. The resting not related to degree oesophagitis nor severity reflux as by 15-hour pH recordings. were...
Summary Background Alisporivir ( ALV ) is an oral, host‐targeting agent with pangenotypic anti‐hepatitis C virus HCV activity and a high barrier to resistance. Aim To evaluate efficacy safety of plus peginterferon‐α2a ribavirin PR in treatment‐naïve patients chronic genotype 1 infection. Methods Double‐blind, randomised, placebo‐controlled, Phase 3 study evaluating 600 mg once daily [response‐guided therapy RGT for 24 or 48 weeks fixed duration] 400 twice , compared alone. Following Food...