Hongyuan Wang

ORCID: 0000-0002-6144-6431
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Research Areas
  • Environmental Toxicology and Ecotoxicology
  • Gut microbiota and health
  • Mercury impact and mitigation studies
  • Amphibian and Reptile Biology
  • Physiological and biochemical adaptations
  • Heavy Metal Exposure and Toxicity
  • Aquaculture disease management and microbiota
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Educational Reforms and Innovations
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Fluoride Effects and Removal
  • Liver Disease Diagnosis and Treatment
  • Genetics, Aging, and Longevity in Model Organisms
  • Cancer-related molecular mechanisms research
  • Microbial Natural Products and Biosynthesis
  • Reproductive biology and impacts on aquatic species
  • MicroRNA in disease regulation
  • Toxic Organic Pollutants Impact
  • Analytical chemistry methods development
  • Fish Biology and Ecology Studies
  • Aquaculture Nutrition and Growth
  • Chemical Analysis and Environmental Impact
  • Circadian rhythm and melatonin
  • Vitamin C and Antioxidants Research

Shaanxi Normal University
2016-2025

Sichuan University of Science and Engineering
2023-2024

Capital Medical University
2018-2024

Gilead Sciences (United States)
2020-2024

Capital University
2024

China University of Mining and Technology
2021-2023

Second Hospital of Liaohe Oilfield
2019-2023

Zhejiang Sci-Tech University
2022

China University of Petroleum, Beijing
2018-2022

Nanjing University of Chinese Medicine
2019-2022

Aging (senescence) is characterized by the development of numerous pathologies, some which limit lifespan. Key to understanding aging discovery mechanisms (etiologies) that cause senescent pathology. In C. elegans, a major pathology unknown etiology atrophy its principal metabolic organ, intestine. Here we identify not only this but also yolky lipid accumulation and redistribution (a form obesity): autophagy-mediated conversion intestinal biomass into yolk. Inhibiting autophagy or...

10.1016/j.cub.2018.06.035 article EN cc-by Current Biology 2018-08-01

Abstract Ageing generates senescent pathologies, some of which cause death. Interventions that delay or prevent lethal pathologies will extend lifespan. Here we identify life-limiting in Caenorhabditis elegans with a necropsy analysis worms have died old age. Our results imply the presence multiple causes Specifically, two classes corpse: early deaths swollen pharynx (which call ‘P deaths’), and later an atrophied (termed ‘p deaths’). The effects interventions on lifespan can be broken down...

10.1038/ncomms15458 article EN cc-by Nature Communications 2017-05-23

Myopia in school-aged children is a public health issue worldwide; consequently, effective interventions to prevent onset and progression are required.To investigate whether SMS text messages parents increase light exposure time outdoors provide myopia control.This randomized clinical trial was conducted China from May 2017 2018, with participants observed for 3 years. Of 528 965 primary Anyang, 3113 were randomly selected. these, 268 grade 2 schoolchildren selected assigned control groups....

10.1001/jamapediatrics.2022.3542 article EN cc-by JAMA Pediatrics 2022-09-26

INTRODUCTION: The results from 2 phase 3 studies, through years, in chronic hepatitis B infection showed tenofovir alafenamide (TAF) had similar efficacy to disoproxil fumarate (TDF) with superior renal and bone safety. We report updated 5 years. METHODS: Patients HBeAg-negative or HBeAg-positive without compensated cirrhosis were randomized (2:1) TAF 25 mg TDF 300 once daily double-blind (DB) fashion for up followed by open-label (OL) 8 Efficacy (antiviral, biochemical, serologic),...

10.14309/ajg.0000000000002468 article EN cc-by-nc-nd The American Journal of Gastroenterology 2023-08-09

Known as the 'third polar region', Qinghai-Tibet Plateau represents one of harshest highland environments in world and yet a number organisms thrive there. Previous studies birds, animals humans have focused on well-differentiated populations later stages phenotypic divergence. The adaptive processes during initial phase adaptation remain poorly understood. We studied human commensal, Eurasian Tree Sparrow, which has followed agriculture to Plateau. Despite strong differentiation at multiple...

10.1093/nsr/nwz138 article EN cc-by National Science Review 2019-09-05

Scope Although the previous trials of inflammation have indicated that morin hydrate (MO) hold considerable promise, understanding distinct mechanism MO against remains a challenge. Methods and results This study investigated effect in atherosclerosis ApoE−/− mice underlying cell signaling human umbilical vein endothelial cells (HUVECs). Administration significantly reduced serum lipid level, inflammatory cytokines (TNF-α ICAM-1), atherosclerotic plaque formation vivo. presence attenuated...

10.1002/mnfr.201600966 article EN Molecular Nutrition & Food Research 2017-04-19

Currently, composting is one of the most effective methods for treating fecal waste on large-scale livestock and poultry farms, but quality effects different are different. In this study, we implemented four methods, including farmer compost (FC), anaerobic (AnC), mixed (MC), aerobic (AC), to study nitrogen (N) losses while dairy manure. Our results showed that germination indexes (GIs) three treatments (AnC, MC, AC) exceeded 80%, which met maturity requirements composted products. Ammonia...

10.3390/ijerph16183324 article EN International Journal of Environmental Research and Public Health 2019-09-09

Purpose: The occurrence and progression of hepatolithiasis are related to inflammatory reactions immune proteins. This study aims evaluate the relationship between systemic index (SII) in recurrence-free survival (RFS), as well incidence severe postoperative complications patients. Patients Methods: We retrospectively analyzed 177 patients with hepatolithiasis. optimal cut-off values SII, response (SIRI), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte (MLR), platelet/lymphocyte (PLR)...

10.2147/jir.s506442 article EN cc-by-nc Journal of Inflammation Research 2025-03-01
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