A5064876086- Mycotoxins in Agriculture and Food
- Reproductive Physiology in Livestock
- Ruminant Nutrition and Digestive Physiology
- Veterinary medicine and infectious diseases
- Effects of Environmental Stressors on Livestock
- Pesticide Residue Analysis and Safety
- Meat and Animal Product Quality
- Microbial infections and disease research
- Genetic and phenotypic traits in livestock
- Wheat and Barley Genetics and Pathology
- Animal Nutrition and Physiology
- Plant Toxicity and Pharmacological Properties
- Animal health and immunology
- Carcinogens and Genotoxicity Assessment
- Liver Disease Diagnosis and Treatment
- Insect and Pesticide Research
- Listeria monocytogenes in Food Safety
- Animal Behavior and Welfare Studies
- Immune Response and Inflammation
- Weed Control and Herbicide Applications
- Reproductive System and Pregnancy
- Fatty Acid Research and Health
- Milk Quality and Mastitis in Dairy Cows
- Metabolism and Genetic Disorders
- Pesticide and Herbicide Environmental Studies
Friedrich-Loeffler-Institut
2015-2024
Animal Health Research Institute
2013-2014
University of Hohenheim
2013
The control of mycotoxins is a global challenge not only in human consumption but also nutrition farm animals including aquatic species. Fusarium toxins, such as deoxynivalenol (DON) and zearalenone (ZEN), are common contaminants animal feed no study reported the occurrence both fish so far. Here, we report for first time DON ZEN samples commercial designed cyprinids collected from central Europe. A maximal concentration 825 μg kg(-1) was found one whereas average values 289 were noted. more...
Subclinical ketosis is a metabolic disorder which often goes undiagnosed and leads to constricted performance an impairment of general condition. In the current study subclinical was characterised by β-hydroxybutyrate (BHB) concentration >1·2 mmol/l in blood serum. To generate this situation, animal model created. The model, based on group-specific interaction dietary energy supply body condition, appropriate for testing medical effectiveness treating kind its concomitants. During trial,...
The mycotoxin zearalenone (ZEN) is frequently contaminating animal feeds including feed used in aquaculture. In the present study, effects of dietary exposure to ZEN on carp (Cyprinus carpio L.) were investigated. at three different concentrations (low dose: 332 µg kg(-1), medium 621 kg(-1) and high 797 final feed, respectively) was administered juvenile for four weeks. Additional groups received same time period but fed with uncontaminated diet two more weeks examine reversibility effects....
Concentrations of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites α-zearalenol (α-ZEL), β-zearalenol (β-ZEL), zearalanone (ZAN), α-zearalanol (α-ZAL), β-zearalanol (β-ZAL) de-epoxy-deoxynivalenol (de-DON) in serum, liquor urine female piglets fed diets containing 0.01, 0.05, 0.08, 0.17 0.29 mg ZEN/kg 0.03, 0.59, 1.27, 2.01 4.52 DON/kg during 29 days treatment were analysed. After 1, 3, 8, 15, 22 days, four per group slaughtered. The simultaneous determination all analytes was...
A dose-response study was carried out to examine the carryover of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites into bovine milk. Therefore, a feeding trial with 30 dairy cows fed three different levels Fusarium (FUS) toxin-contaminated maize performed. control group (0.02 mg ZEN kg(-1) dry matter (DM) 0.07 DON DM) compared two groups contaminated diets. The first diet contained 0.33 DM 2.62 (group FUS-50) second 0.66 5.24 FUS-100). For milk sample analysis, new...
Infrared imaging proves to be a quick and simple method for measuring temperature distribution on the pig's head. The study showed that infrared analysis with difference ROI (region of interest) may used early detection elevated body in pigs (> 39.5°C). A high specificity approx. 85% sensitivity 86% existed. only prerequisite is there are at least 2 anatomical regions which can recognised as reproducible IR image. Noise suppression guaranteed by averaging value within both these ROI....
Using an established model in which subclinical ketosis is induced, the response of differential blood counts and levels various haematological variables, including inflammatory marker haptoglobin (Hp), were tested over last six weeks parturition until 56th day post-partum cows with lower or higher body condition scores (LBC HBC, respectively; n = 9/group). Animals HBC group evidenced whereas LBC animals metabolically healthy. For vitro examination ß-hydroxybutyrate (BHB) as a further...
Dairy cows are metabolically challenged during the transition period. Furthermore, process of parturition represents an energy-consuming process. The degree negative energy balance and recovery from calving also depends on efficiency mitochondrial generation. At this point, L-carnitine plays important role for transfer fatty acids to site their utilisation. A control (n = 30) group 29, 25 g rumen-protected per cow day) were created blood samples taken day 42 ante partum (ap) until 110...
Fusarium infections do not only affect the grain, but also rest of plant, which result in contamination plants with mycotoxin deoxynivalenol (DON). The bioavailability DON may be influenced by matrix due to differences nutrient composition between grain and straw, particularly high fibre component straw. experiment was carried out exposing 18 male castrated pigs (30-40 kg live weight) a single dose from wheat straw chaff diet. courses serum concentrations were evaluated using toxicokinetic...
Summary To investigate the usefulness of follicular fluid ( FF ) in relation to blood plasma and bile as indicators exposure dairy cows ZEN , DON their metabolites, a dose–response study was performed with 30 cows. The cows, 10 each group (named CON ; FUS ‐50, ‐100), received diet three different concentrations Fusarium toxin‐contaminated maize. Thereby, following dietary concentration were reached: (0.02 mg 0.07 per kg dry matter, DM ), ‐50 (0.33 2.62 ‐100 (0.66 5.24 ). de‐epoxy‐ (de‐...
We investigated a proposed synergistic effect of deoxynivalenol (DON) and lipopolysaccharides (LPS) on small intestinal architecture epithelial barrier integrity in pigs. Crypt depth cell proliferation were analyzed, as well expression zonula occludens protein-1 (ZO-1) β-catenin the apical junction complex along intestine. Barrows (26.2±4.1 kg) fed restrictedly either control diet (CON) or naturally contaminated with 3.1 mg DON/kg feed for 37 d. At d 37, group was infused 1 h 100 μg/kg BW...
It is well observed that feeding energy-dense diets in dairy cows during the dry period can cause metabolic imbalances after parturition. Especially with high body condition score (BCS) and fed an diet were prone to develop production diseases due disturbances postpartum. An experiment was conducted determine effects of nicotinic acid (NA) on variables primiparous multiparous late pregnancy early lactation which not pre-selected for BCS. Thirty-six 20 German Holstein equal conditions (60%...
Abstract Following the use of sugar beet pulp that was retrospectively found to be predominantly contaminated with zearalenone (ZEN) in diets reproducing sows largely exceeding EU-guidance value for critical ZEN concentration 0.25 mg/kg, farmers did not report any changes reproductive performance sows. Thus, aim study verify this guidance a dose–response setup by using as source hitherto considered risky feedstuff additionally characterized comparatively low levels deoxynivalenol. A total 90...
A feeding trial with 30 dairy cows which were fed rations three different concentrations of zearalenone (ZEA) and deoxynivalenol (DON) contaminated maize was carried out to examine the ZEA DON concentration in urine. German Holstein (n=30) divided into groups (n=10 each) received diets following toxin concentrations: CON (0.02 mg 0.07 DON, per kg dry matter (DM)), FUS-50 (0.33 2.62 DM), FUS-100 (0.66 5.24 DM). For urine analysis, a reliable, cost-efficient sensitive method for simultaneous...
Previous studies have shown that chronic oral deoxynivalenol (DON) exposure modulated Escherichia coli lipopolysaccharide (LPS)-induced systemic inflammation, whereby the liver was suspected to play an important role. Thus, a total of 41 barrows fed one two maize-based diets, either DON-diet (4.59 mg DON/kg feed, n = 19) or control diet (CON, 22). Pigs were equipped with indwelling catheters for pre- post-hepatic (portal vs. jugular catheter) infusion (0.9% NaCl) LPS (7.5 µg/kg BW) 1h and...
Summary The periparturient period is accompanied by metabolic and oxidative stress. Niacin known to decrease lipolysis but also reported have anti‐oxidative effects. Therefore, we examined the effects of energy supply a nicotinic acid ( NA ) supplementation on serum parameters expression stress‐related genes in blood leucocytes dairy cows, differing parity. Twenty‐nine pluriparous 18 primiparous cows were allocated four different feeding groups 42 days before expected parturition until 100...