A5016325133- Ruminant Nutrition and Digestive Physiology
- Reproductive Physiology in Livestock
- Effects of Environmental Stressors on Livestock
- Mycotoxins in Agriculture and Food
- Animal Nutrition and Physiology
- Animal health and immunology
- Genetic and phenotypic traits in livestock
- Metabolism and Genetic Disorders
- Veterinary medicine and infectious diseases
- Pesticide and Herbicide Environmental Studies
- Microbial infections and disease research
- Weed Control and Herbicide Applications
- Meat and Animal Product Quality
- Cancer-related molecular mechanisms research
- Livestock and Poultry Management
- Immune Response and Inflammation
- Animal Behavior and Welfare Studies
- Gut microbiota and health
- Pluripotent Stem Cells Research
- Agriculture and Biological Studies
- Liver Disease Diagnosis and Treatment
- Reproductive System and Pregnancy
- Rabbits: Nutrition, Reproduction, Health
- Milk Quality and Mastitis in Dairy Cows
- Clostridium difficile and Clostridium perfringens research
Friedrich-Loeffler-Institut
2016-2025
University of Rostock
2006-2011
Max Planck Institute for Biophysical Chemistry
1992
Max Planck Society
1992
Subclinical ketosis is a metabolic disorder which often goes undiagnosed and leads to constricted performance an impairment of general condition. In the current study subclinical was characterised by β-hydroxybutyrate (BHB) concentration >1·2 mmol/l in blood serum. To generate this situation, animal model created. The model, based on group-specific interaction dietary energy supply body condition, appropriate for testing medical effectiveness treating kind its concomitants. During trial,...
Abstract The aim of the present study is to investigate whether extremely low frequency electromagnetic fields (ELF‐EMF) affect certain cellular functions and immunologic parameters mouse macrophages. In this study, influence 50 Hz magnetic (MF) at 1.0 mT was investigated on phagocytic activity interleukin‐1β (IL‐1β) production in differentiated MF‐exposure led an increased after 45 min, shown as a 1.6‐fold uptake latex beads MF‐exposed cells compared controls. We also demonstrate IL‐1β...
Excessive mobilization of body reserves during the transition from pregnancy to lactation imposes a risk for metabolic diseases on dairy cows. We aimed establish an experimental model high v. normal and herein characterized performance, endocrine changes 7 weeks antepartum (a.p.) 12 postpartum (p.p.). Fifteen a.p., 38 pregnant multiparous Holstein cows were allocated two groups that fed differently reach either or condition scores (HBCS: 7.2 NEL MJ/kg dry matter (DM); NBCS: 6.8 DM) at...
Abstract Background The rumen bacterial communities are changing dynamically throughout the first year of calf’s life including weaning period as a critical event. Rumen microbiome analysis is often limited to invasive sampling procedures but oral cavity ruminants expected harbour microbes due regurgitation activity. present study used buccal swab samples define core and characterize shifts in microbial occurring result age well time weaning. Results Buccal 59 calves were collected along 140...
Calves undergo nutritional, metabolic, and behavioural changes from birth to the entire weaning period. An appropriate selection of age is essential reduce negative effects caused by weaning-related dietary transitions. This study monitored faecal microbiome plasma metabolome 59 female Holstein calves during different developmental stages times (early vs. late) identified potential associations measured parameters over an experimental period 140 days.A progressive development was observed...
ABSTRACT Bone damages in laying hens are of great concern poultry farming. Besides various risk factors like housing systems or nutrient supply during egg production, it has often been hypothesized that genetically high‐performing may be more prone to bone damages. The relevance dietary support the rearing period pullets for optimal development little addressed so far. In present study, an increasing vitamin D 3 content within EU legislation was tested first 12 weeks life two high and...
This work examined preventive effects of a dietary and medical intervention measure on postpartum (p.p.) ketogenesis in dairy cows overconditioned late pregnancy. Sixty German Holstein were allocated 6 weeks antepartum (a.p.) to three high body condition score (BCS) groups (BCS 3.95 ± 0.08) one low BCS group (LC, 2.77 0.14). Concentrate proportion diet a.p. was higher (60% vs. 20%) increase p.p. from 30% up 50% decelerated (3 2 weeks) groups. High received monensin controlled-release capsule...
Abstract ReNcell VM is an immortalized human neural progenitor cell line with the ability to differentiate in vitro into astrocytes and neurons, which Wnt/β-catenin pathway known be involved. However, little about kinetic changes of this differentiation. In present study, we provide a quantitative profile dynamics showing its spatio-temporal regulation during We show first that T-cell factor dependent transcription can activated by stabilized β-catenin. Furthermore, endogenous Wnt ligands,...
Summary The aim of the present study was to assess performance traits chicken lines with different level and phylogenetic origin. Selection for high performances may change unselected related animal health well-being. However, long before intense selection started act leading contemporary performing genotypes, founder populations on egg laying breeds white brown shell had been separated many generations have evolved independently. We set up a comprehensive collaborative effort at...
Using an established model in which subclinical ketosis is induced, the response of differential blood counts and levels various haematological variables, including inflammatory marker haptoglobin (Hp), were tested over last six weeks parturition until 56th day post-partum cows with lower or higher body condition scores (LBC HBC, respectively; n = 9/group). Animals HBC group evidenced whereas LBC animals metabolically healthy. For vitro examination ß-hydroxybutyrate (BHB) as a further...
Summary Using a model to generate experimental groups with different manifestations of post‐partum (p.p.) fat mobilization and ketogenesis, the effects dietary medical intervention on biochemical haematological parameters, antibody titre, leucocytes subsets function transition cows were examined. In total, 60 German Holstein allocated 6 weeks antepartum (a.p.) 3 high‐body condition score ( BCS ) 3.95) 1 low‐ group LC , 2.77). High‐ received monensin controlled‐release capsule HC / MO or...
Dairy cows are metabolically challenged during the transition period. Furthermore, process of parturition represents an energy-consuming process. The degree negative energy balance and recovery from calving also depends on efficiency mitochondrial generation. At this point, L-carnitine plays important role for transfer fatty acids to site their utilisation. A control (n = 30) group 29, 25 g rumen-protected per cow day) were created blood samples taken day 42 ante partum (ap) until 110...
AbstractMany health effects can be attributed to the Mediterranean herb oregano (Origanum vulgare L.) and several studies demonstrated improving effect on performance, changes in blood count, antibacterial, antifungal immunmodulating abilities. The majority of these investigations were carried out with processed essential oil, while whole plant material was only used a few studies. Thus, aim present experiment test increasing proportions dried piglet feed special focus immune modulation. A...
It is well observed that feeding energy-dense diets in dairy cows during the dry period can cause metabolic imbalances after parturition. Especially with high body condition score (BCS) and fed an diet were prone to develop production diseases due disturbances postpartum. An experiment was conducted determine effects of nicotinic acid (NA) on variables primiparous multiparous late pregnancy early lactation which not pre-selected for BCS. Thirty-six 20 German Holstein equal conditions (60%...
The mycotoxin fumonisin B1 (FB1) is a frequent contaminant of feed. It causes disruption sphingolipid metabolism and pulmonary, hepatic, immunological lesions in pigs depending on the exposure scenario. One sensitive biomarker for FB1 sphinganine (Sa) to sphingosine (So) ratio blood. esterase FumD, which can be used as feed additive, converts into much less toxic metabolite hydrolyzed (HFB1). We conducted single-dose study with barrows allocated one five treatments: (1) control (feed, 0.9%...
ABSTRACTVitamin D3 has an integral part in calcium and phosphorus homoeostasis, which turn plays a key role egg production of hens. The present study aimed to investigate whether additional vitamin supplementation improves the laying performance quality hens according their genetic potential. For this purpose, four layer lines (low performing: R11 L68; high WLA BLA) supplemented either with 300 or 3000 IU per kg feed were compared concerning serum 25-hydroxyvitamin (25-OHD3), calcium,...