- Reproductive Physiology in Livestock
- Effects of Environmental Stressors on Livestock
- Ruminant Nutrition and Digestive Physiology
- Genetic and phenotypic traits in livestock
- Growth Hormone and Insulin-like Growth Factors
- MicroRNA in disease regulation
- Adipokines, Inflammation, and Metabolic Diseases
- Hypothalamic control of reproductive hormones
- Regulation of Appetite and Obesity
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
University of Bonn
2016-2019
Excessive mobilization of body reserves during the transition from pregnancy to lactation imposes a risk for metabolic diseases on dairy cows. We aimed establish an experimental model high v. normal and herein characterized performance, endocrine changes 7 weeks antepartum (a.p.) 12 postpartum (p.p.). Fifteen a.p., 38 pregnant multiparous Holstein cows were allocated two groups that fed differently reach either or condition scores (HBCS: 7.2 NEL MJ/kg dry matter (DM); NBCS: 6.8 DM) at...
The objective of this study was to examine the effect nutrition during first 18 weeks life on physiological and transcriptional functionality hypothalamic (arcuate nucleus region), anterior pituitary testes in Holstein–Friesian bull calves. calves with a mean (±S.D.) age bodyweight 19 (±8.2) days 47.5 (±5.3) kg, respectively, were assigned either HIGH (n = 10) or LOW plane nutrition, achieve an overall target growth rate 1.2 0.5 kg/day, respectively. At 126 ± 1.1 age, all euthanised. Animal...
Circulating microRNA (miRNA) may provide insight into physiological or pathophysiological statuses and the underlying metabolic pathways. Our objective was to characterize miRNA serum profile in dairy cows with normal versus high body condition score (BCS). Thirty pluriparous Holstein were preselected 15 wk before calving for either BCS (HBCS > 3.75, NBCS < 3.5 at calving). A comparative analysis of extracted from obtained d -49 +21 relative (three pools five each per time point group) done...
The peripartal decrease of insulin sensitivity in peripheral tissues other than the mammary gland facilitates draining glucose towards at that time. Adiponectin is an insulin-sensitizing adipokine; its concentrations around parturition dairy cows. Based on different metabolic stress primiparous (PP) and multiparous (MP) cows (PP are still growing, MP have more milk), we hypothesized serum adiponectin dry period subsequent lactation will be greater PP Blood was sampled -50, -14, 8, 28, 100...