- Reproductive Physiology in Livestock
- Effects of Environmental Stressors on Livestock
- Ruminant Nutrition and Digestive Physiology
- Animal health and immunology
- Genetic and phenotypic traits in livestock
- Adipose Tissue and Metabolism
- Fatty Acid Research and Health
- Infant Nutrition and Health
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Growth Hormone and Insulin-like Growth Factors
- Animal Nutrition and Physiology
- Milk Quality and Mastitis in Dairy Cows
- Pharmacological Effects and Assays
- Meat and Animal Product Quality
- Hormonal and reproductive studies
- Cancer-related molecular mechanisms research
- Animal Behavior and Welfare Studies
- Muscle metabolism and nutrition
- Birth, Development, and Health
- MicroRNA in disease regulation
- Peroxisome Proliferator-Activated Receptors
- Hemoglobin structure and function
- Veterinary Equine Medical Research
- Extracellular vesicles in disease
University of Bonn
2016-2025
Unité Mixte de Recherche sur les Herbivores
2023
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2023
Research Institute for Farm Animal Biology (FBN)
2020
University of Tabriz
2017
European Federation of Animal Science
2014
Azienda Sanitaria Locale Roma 3
2014
Martin Luther University Halle-Wittenberg
2010
Institute of Animal Science
2008
GTx (United States)
2007
This study was conducted to investigate individual metabolic and endocrine adaptation lactation under conditions of identical housing feeding in high-yielding dairy cows. Forty-five cows were studied on a research farm standardized but practical conditions. From wk 2 before calving until 14 postpartum, blood samples collected at weekly intervals assayed for chemistry various metabolites hormones. Body weight, BCS, backfat thickness also recorded weekly. Milk yield, milk composition, feed...
Summary. The effect of insulin-like growth factors (IGFs) and insulin on the release progesterone oxytocin from bovine corpus luteum was investigated at early (days 5–7), mid- 8–12) late 15–18) luteal phases oestrous cycle in an vitro microdialysis system. expression specific receptors evaluated corpora lutea respective stages. A 30 min infusion IGF-1, IGF-2 (1·3, 13 130 nmol l−1) or (13, 1300 caused a stimulation (P < 0·05). IGF-1 most effective releasing progesterone. Oxytocin stimulated...
Serum chemistry reference values may provide useful information about the physical condition of individuals, making them a tool in differentiating normal and healthy animals from abnormal or diseased states. For Japanese quail that are used for producing eggs meat human consumption also as laboratory animals, we aimed to extend available array compare 16-wk-old adult male versus female birds. In present study, clinical data (albumin, total protein, glucose, uric acid, cholesterol, bilirubin,...
In dairy cows the milk associated energy output in early lactation exceeds input via voluntary feed intake. To spare glucose for mammary lactose synthesis, peripheral insulin sensitivity (IS) is reduced and fat mobilization stimulated. For these processes a link between IS endocrine functions of adipose tissue (AT) likely; we thus aimed to characterise mRNA expression from bovine AT derived proteins receptors that are related according literature metabolically active tissues plus systemic...
Adiponectin and intracellular 5'adenosine monophosphate-activated protein kinase (AMPK) are important modulators of glucose fat metabolism. Cinnamon exerts beneficial effects by improving insulin sensitivity blood lipids, e.g., through increasing adiponectin concentrations AMPK activation. The underlying mechanism is unknown. Gi/Go-protein-coupled receptor (GPR) 109A stimulates secretion after binding its ligand niacin. Trans-cinnamic acid (tCA), a compound cinnamon another ligand. We...
Excessive mobilization of body reserves during the transition from pregnancy to lactation imposes a risk for metabolic diseases on dairy cows. We aimed establish an experimental model high v. normal and herein characterized performance, endocrine changes 7 weeks antepartum (a.p.) 12 postpartum (p.p.). Fifteen a.p., 38 pregnant multiparous Holstein cows were allocated two groups that fed differently reach either or condition scores (HBCS: 7.2 NEL MJ/kg dry matter (DM); NBCS: 6.8 DM) at...
The composition of milk replacer (MR) for calves greatly differs from that bovine whole milk, which may affect gastrointestinal development young calves. In this light, the objective current study was to compare tract structure and function in response feeding liquid diets having a same macronutrient profile (e.g., fat, lactose, protein) first month life. Eighteen male Holstein (46.6 ± 5.12 kg; 1.4 0.50 d age at arrival; mean standard deviation) were housed individually. Upon arrival,...
Extracellular vesicles (EV) are membranous considered as significant players in cell-to-cell communication. Milk provides adequate nutrition, transfers immunity, and promotes neonatal development, milk EV suggested to play a crucial role these processes. samples were obtained on days 0, 7, 14 after parturition from sows receiving either standard diet (ω-6:ω-3 = 13:1) or test enriched ω-3 4:1). isolated using ultracentrifugation coupled with size exclusion chromatography, characterized by...
Background/Objectives: Clinical experience indicates that determination of interleukin 6 (IL-6) in human blood can vary depending on time span between sample collection and centrifugation. Here, we have evaluated confounding effect various specimen. Methods: Measurement IL-6 before after pre-centrifugation incubation (20 °C, 24 - 72 h) heparin-plasma, serum EDTA-plasma from healthy individuals critical ill patients. Results: Pre-incubation induced increases heparin-plasma (in 17/20 samples...
The fecal metabolome comprises metabolites that are excreted or not absorbed by the animal. This study examined changes in of dairy cows from end one lactation period, through dry and into subsequent lactation. Twelve Holstein (BW = 745 ± 71 kg, BCS 3.43 0.66) were housed a tie-stall barn 7 wk before to 15 after parturition, with dry-off occurring approximately 6 expected calving date (mean time 42 d). Fecal samples taken at -7, -5, -1, +1, +5, +10, +15 relative calving. Targeted...