A5051853276- Animal Behavior and Welfare Studies
- Reproductive Physiology in Livestock
- Animal Nutrition and Physiology
- Effects of Environmental Stressors on Livestock
- Stress Responses and Cortisol
- Genetic and phenotypic traits in livestock
- Meat and Animal Product Quality
- Adipose Tissue and Metabolism
- Ruminant Nutrition and Digestive Physiology
- Reproductive Biology and Fertility
- Fatty Acid Research and Health
- Human-Animal Interaction Studies
- Neuroendocrine regulation and behavior
- Animal health and immunology
- Sperm and Testicular Function
- Infant Nutrition and Health
- Genetic Mapping and Diversity in Plants and Animals
- Growth Hormone and Insulin-like Growth Factors
- Primate Behavior and Ecology
- Sarcoma Diagnosis and Treatment
- Toxin Mechanisms and Immunotoxins
- Birth, Development, and Health
- Animal Vocal Communication and Behavior
- Tryptophan and brain disorders
- Ovarian function and disorders
Research Institute for Farm Animal Biology (FBN)
2015-2024
Zimmer Biomet (Germany)
2011-2024
University Hospital Cologne
2012-2024
University of Cologne
2012-2024
Düsseldorf University Hospital
2021-2024
Heinrich Heine University Düsseldorf
2021-2024
Cambridge University Press
2022
New York University Press
2022
Leibniz Association
2010-2015
Centrum für Integrierte Onkologie
2015
The optimal treatment for advanced leiomyosarcoma is still debated. Given histotype-specific prospective controlled data lacking, this study retrospectively evaluated doxorubicin plus dacarbazine, ifosfamide, and alone as first-line treatments advanced/metastatic treated at European Organization Research Treatment of Cancer Soft Tissue Bone Sarcoma Group (EORTC-STBSG) sites.The inclusion criteria were a confirmed histological diagnosis, between January 2010 December 2015, measurable disease...
During the last two decades, hair cortisol concentration (HCC) has proven to be a promising marker for evaluation of increased hypothalamic-pituitary-adrenal axis activity caused by repeated or long-term stressful conditions. A minimally invasive sampling procedure, simple storage and retrospective characteristic one sample are reasons why HCC is increasingly used not only in human medicine but also animal welfare research. However, before applying as reliable indicator stress, it important...
Abstract Background Fibroblast activation protein (FAP) is expressed in the tumor microenvironment (TME) of various cancers. In our analysis, we describe impact dual-tracer imaging with Gallium-68-radiolabeled inhibitors FAP (FAPI-46-PET/CT) and fluorodeoxy-D-glucose (FDG-PET/CT) on radiotherapeutic management primary esophageal cancer (EC). Methods 32 patients EC, who are scheduled for chemoradiation, received FDG FAPI-46 PET/CT same day (dual-tracer protocol, 71%) or two separate days...
Indoleamine 2,3-dioxygenase (IDO) is a rate-limiting enzyme for the degradation of tryptophan (Trp) along kynurenine (Kyn) pathway, and its increased activation associated with immunologic disorders. Because specific role IDO not yet completely clear, aim present study was to establish pig model further research. The in pigs induced experimentally by LPS stimulation vivo ex vivo. characterized measuring Trp, Trp metabolites protein expression blood, liver, lung, muscle different brain areas....