A5039836191- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Lymphatic System and Diseases
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Facial Trauma and Fracture Management
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- Body Contouring and Surgery
- Systemic Sclerosis and Related Diseases
- dental development and anomalies
- Breast Implant and Reconstruction
- Lymphatic Disorders and Treatments
- Diagnosis and Treatment of Venous Diseases
- Cutaneous Melanoma Detection and Management
- Myofascial pain diagnosis and treatment
- Orthodontics and Dentofacial Orthopedics
- Ophthalmology and Eye Disorders
- Sympathectomy and Hyperhidrosis Treatments
- History of Medical Practice
- Facial Nerve Paralysis Treatment and Research
- Aerospace and Aviation Technology
- Anatomy and Medical Technology
- Connective tissue disorders research
Zhejiang Normal University
2024-2025
Yale University
2019-2024
Mayo Clinic in Florida
2019-2022
Creative Commons
2019-2022
Yale New Haven Hospital
2022
Dalian Medical University
2022
Nanjing University of Aeronautics and Astronautics
2022
JDSU (United States)
2021
New York Medical College
2020-2021
Mayo Clinic in Arizona
2020-2021
Medicinal plants, recognized as significant natural resources, have gained prominence in response to the increasing global demand for herbal medicines, necessitating large-scale production of these plants and their derivatives. are exposed a variety internal external factors that interact influence biosynthesis accumulation secondary metabolites. With rapid development omics technologies such genomics, transcriptomics, proteomics, metabolomics, multi-omics become important tools revealing...
Background: De novo or rare transmitted mutations in the SMAD6 gene affect 7 percent of midline nonsyndromic synostosis patients. This study aimed to determine neurocognitive sequelae synostosis. Methods: Nonsyndromic patients 6 years older with and non- controls were recruited. All completed a double-blinded neurodevelopmental battery (i.e., Wechsler Fundamentals, Abbreviated Scale Intelligence, Beery-Buktenica Developmental test), parents/guardians behavioral surveys (Behavior Rating...
Apert syndrome patients are different in clinical pathology, including obstructive sleep apnea, cleft palate, and mental deficiency. These functional deficiencies may be due to anatomic deformities, which caused by forms of associated suture fusion. Therefore, a classification system based on the type craniosynostosis pattern might helpful determining treatment choices.CT scans 31 unoperated 51 controls were included subgrouped as: class I. Bilateral coronal synostosis; II. Pansynostosis;...
Background: Considerable craniofacial features of Crouzon syndrome are attributed to the dysmorphology cranial base. As cephalometric studies have focused mainly on facial deformity, rather than base, underlying cause deformity is not as well understood. Therefore, authors compared base development controls trace timing in and face, analyze their temporal correlation. Methods: Ninety computed tomographic scans were included (Crouzon, n = 36; controls, 54) divided into five age subgroups....
Crouzon syndrome is associated with severe respiratory impairment of the upper airway due in part to midfacial dysmorphology. We calculated distinctive nasal diameter and pharyngeal volume patients compared them age-matched control subjects.Children computed tomography scans absence surgical intervention were included. Computed digitized manipulated using Surgicase CMF (Materialise). Craniometric data relating midface collected. For all linear measurements, mean percent increases or...
Abstract Numerous large scale genomic studies have uncovered rare but recurrent pathogenetic variants in a significant number of genes encoding epigenetic machinery cases with neurodevelopmental disorders (NDD) especially autism spectrum disorder (ASD). These findings provide strong support for the functional importance regulators neurodevelopment. After clinical genomics evaluation patients using exome sequencing, we identified, three novel protein-truncating (PTVs) MSL2 gene (OMIM: 614802)...
Background: Apert syndrome is frequently combined with respiratory insufficiency, because of the midfacial deformity which, in turn, influenced by malformation skull base. Respiratory impairment resulting from caused multilevel limitations airway space. Therefore, this study evaluated segmented nasopharyngeal and laryngopharyngeal anatomy to clarify subcranial children its relevance clinical management. Methods: Twenty-seven patients (Apert syndrome, n = 10; control, 17) were included. All...
Background: Patients with Crouzon syndrome develop various types of anatomic deformities due to different forms craniosynostosis, yet they have similar craniofacial characteristics. However, exact homology is not evident. Different pathology then may be best treated by surgical technique. Therefore, precise classification syndrome, based on individual patterns cranial suture involvement needed. Methods: Ninety-five computed tomography (CT) scans (Crouzon, n = 33; control, 62) were included...
Background: Apert syndrome causes normal or enlarged intracranial volume overall as patients grow. This study aimed to trace the segmental anterior, middle, and posterior cranial fossae structural morphology in these patients, help discern a more focused individualized surgical treatment plan for with syndrome. Methods: included 82 preoperative computed tomographic scans (Apert, n = 32; control, 50) divided into five age-related subgroups. The were measured using image processing...
In Crouzon's syndrome, cranial base deformities begin sequentially in the anterior fossa initially, and later to posterior base. Facial characteristics are likely related development. The temporal correlation between development facial features is need of clarification patients, clarify initial sites deformity, which may impact surgical decision making.Thirty-six computed tomography scans unoperated syndrome patients 54 controls were included divided into 5 age-subgroups. All planes used for...
From infancy to adulthood, the mandible develops increased ramus height, prominence of chin, and laterally widened gonial angles. In Crouzon Apert syndromes, both relative retrognathia prognathic jaws have been reported. Growth is influenced by a variety factors, including growth position skull base, functional coordination, spatial influence laryngopharynx. Thus, this study aimed explore in detail evolution syndromes its relationship with entire facial structure base.One hundred...
BACKGROUND: Paget’s disease of the breast is rare. The National Cancer Database (NCDB) one largest tumor databases in United States. METHODS: We queried NCDB to identify male and female patients with who were treated from January 1, 2004, through December 31, 2015. No age limitations applied. Descriptive statistical analysis survival performed. RESULTS: analyzed demographic, disease, treatment characteristics 7,191 breast. median (range) was 64 (20–90) years. Only 2.1% men, 85.4% white. most...
Facial Feminization Surgery (FFS) alters bone and soft tissue to feminize facial features of transgender females. This study aims evaluate perceptions femininity, attractiveness, ideal surgical outcomes in females, non-transgender females plastic surgeons.The data was extracted from a survey (n=104), (n=192) (completion rate 48.4%) surgeons who performed FFS (n=23) (survey response 31.5%). Five virtually-modified forms three features, the nasal tip width, supratip break, mandibular gonial...