Hongxiu Xiao

ORCID: 0000-0003-2052-5261
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Marine Sponges and Natural Products
  • Microbial Natural Products and Biosynthesis
  • Microbial Community Ecology and Physiology
  • Marine Biology and Ecology Research
  • Environmental DNA in Biodiversity Studies
  • Ocean Acidification Effects and Responses
  • Plant Pathogens and Fungal Diseases
  • Eosinophilic Esophagitis
  • Plant biochemistry and biosynthesis
  • Bioactive Natural Diterpenoids Research
  • Asthma and respiratory diseases
  • Phytochemistry and Bioactive Compounds
  • Seaweed-derived Bioactive Compounds
  • Food Allergy and Anaphylaxis Research
  • Petri Nets in System Modeling
  • Bioactive Compounds and Antitumor Agents
  • Advanced Data Processing Techniques
  • Fault Detection and Control Systems

University of Hong Kong
2024

Fujian Institute of Oceanography
2020-2024

Xiamen University
2021-2024

Hong Kong University of Science and Technology
2024

Ministry of Natural Resources
2020-2024

Collaborative Innovation Center of Chemistry for Energy Materials
2021

Hainan University
2021

Zhejiang University
2013

Vestimentiferan tubeworms that thrive in deep-sea chemosynthetic ecosystems rely on a single species of sulfide-oxidizing gammaproteobacterial endosymbionts housed specialized symbiotic organ called trophosome as their primary carbon source. While this simple symbiosis is remarkably productive, the host-symbiont molecular interactions remain unelucidated. Here, we applied an approach for situ single-cell fixation cold-seep tubeworm,

10.1126/sciadv.adn3053 article EN cc-by-nc Science Advances 2024-07-24

The first total synthesis of marine natural product, (−)-majusculoic acid (1) and its seven analogs (9–15), was accomplished in three to ten steps with a yield 3% 28%. strategy featured the application conformational controlled establishment trans-cyclopropane stereochemical bromo-olefination or olefination by Horner–Wadsworth–Emmons (HWE) reaction. potential anti-inflammatory activity eight compounds (1 9–15) evaluated determining nitric oxide (NO) production lipopolysaccharide...

10.3390/md19060288 article EN cc-by Marine Drugs 2021-05-21

Food allergy (FA) poses a growing global food safety concern, yet no effective cure exists in clinics. Previously, we discovered potent antifood compound, butyrolactone I (BTL-I,

10.1021/acs.jmedchem.4c00354 article EN Journal of Medicinal Chemistry 2024-04-19

One new (d-arabinitol-anofinicate, 1) and fourteen known (2-15) compounds were isolated from the marine Penicillium sp. MCCC 3A00228. The structure of compound was established mainly by extensive spectroscopic analyses. Compound 1 exhibited weak transcriptional effect on Nur77. While 13 showed moderate in vitro anti-proliferative against QGY7701, H1299, HCT116 tumor cells with IC50 values 21.2 μM, 18.2 17.6 respectively.

10.1002/cbdv.202100697 article EN Chemistry & Biodiversity 2021-09-29

Abstract A unique polyketide cladosporactone along with eight known compounds were isolated from the deep‐sea‐derived Cladosporium cladosporioides . The structure of was established by spectroscopic analyses, and absolute configuration clarified theoretical ECD calculation. Cladosporactone is first member 7‐methylisochromen‐3‐one skeleton.

10.1002/cbdv.202000158 article EN Chemistry & Biodiversity 2020-04-07

Open AccessCCS ChemistryRESEARCH ARTICLE1 Mar 2022Total Synthesis of Stemarene and Betaerene Diterpenoids: Divergent Ring-Formation Strategy Late-Stage C–H Functionalization Renzhi Chen†, Feng Zhang†, Yuhui Hua†, Dong Shi, Xin Lei, Hongxiu Xiao, Yinong Wang, Shihao Ding, Yang Shen Yandong Zhang Chen† Department Chemistry, Chemical Biology, Key Laboratory Biology Fujian Province, iChEM, College Chemistry Engineering, Xiamen University, Xiamen, 361005 , Zhang† Hua† Shi Lei Xiao Wang Ding...

10.31635/ccschem.021.202100821 article EN cc-by-nc CCS Chemistry 2021-03-29

In networked automation systems, network plays a central role in information exchange. The error local system will directly or indirectly affect other parts of the system, which may induce faults. this paper, novel data driven root cause analysis method for intermittent connection faults, common but difficult troubleshooting problem controller area (CAN), is developed systems. Using discrete random process theory and quasi-period pattern recognition method, reasoning algorithm that...

10.1109/cac.2013.6775747 article EN Chinese Automation Congress 2013-11-01
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