A5045330783- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Microbial Natural Products and Biosynthesis
- Legume Nitrogen Fixing Symbiosis
- Microbial Metabolism and Applications
- Marine Sponges and Natural Products
- Lipid metabolism and biosynthesis
- Plant Disease Resistance and Genetics
- Bacteriophages and microbial interactions
- Enzyme Production and Characterization
- Salmonella and Campylobacter epidemiology
- Plant Pathogens and Fungal Diseases
- Protist diversity and phylogeny
- Algorithms and Data Compression
- Machine Learning in Bioinformatics
- Plant nutrient uptake and metabolism
- Identification and Quantification in Food
- Coastal wetland ecosystem dynamics
- Nematode management and characterization studies
- Oral microbiology and periodontitis research
- Plant-Microbe Interactions and Immunity
- RNA and protein synthesis mechanisms
- Environmental DNA in Biodiversity Studies
- Fungal Biology and Applications
- Aquaculture disease management and microbiota
Zhejiang Sci-Tech University
2018-2025
University of Pennsylvania
2021-2025
Second Institute of Oceanography
2014-2024
Ministry of Natural Resources
2015-2024
Fujian Institute of Oceanography
2021-2024
Tohoku University
2024
University of York
2023
Southwest University
2023
Shaoxing University
2022-2023
Hexi University
2014-2023
Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) represents the 2019 merger of VectorBase with EuPathDB projects. As a Bioinformatics Center funded by National Institutes Health, additional support from Welllcome Trust, VEuPathDB supports >500 organisms comprising invertebrate vectors, eukaryotic pathogens (protists fungi) relevant free-living or non-pathogenic species hosts. Designed to empower researchers access Omics data...
The family Erythrobacteraceae , belonging to the order Sphingomonadales class Alphaproteobacteria is globally distributed in various environments. Currently, this consist of seven genera: Altererythrobacter Croceibacterium Croceicoccus Erythrobacter Erythromicrobium Porphyrobacter and Qipengyuania . As more species are identified, taxonomic status should be revised at genomic level because its polyphyletic nature evident from 16S rRNA gene sequence analysis. Phylogenomic reconstruction based...
Endophytic bacteria associated with medicinal plants possess unique strategies that enhance growth and suvival of host plants, many which are mediated by distinctive secondary metabolites. These their metabolites important subjects for both basic applied research aimed at sustainable agriculture. In the present study, 114 endophytic strains isolated from wild ethnomedicinal plant Glycyrrhiza uralensis (licorice) were screened in vitro antimicrobial activities against common fungal pathogens...
The members of the phylum Bacteroidetes are recognized as some most important specialists for degradation polysaccharides. However, in contrast to research on human gut, polysaccharide by marine is still rare. genus Algibacter belongs Flavobacteriaceae family Bacteroidetes, and species this isolated from or near habitat algae, indicating a preference complex polysaccharides algae. In work, novel brown-seaweed-degrading strain designated HZ22 was surface brown seaweed (Laminaria japonica). On...
To develop safe and cheap thrombolytic agents, a fibrinolytic enzyme productive strain of LSSE-62 was isolated from Chinese soybean paste. This identified as Bacillus amyloliquefaciens by 16S rDNA sequence analysis. Nucleotide amino acid analysis showed that this identical to subtilisin DJ-4. Chickpeas were used the substrate for production B. in solid-state fermentation. Under optimized conditions (34 °C 50% initial moisture content), activity fermented chickpeas reached 39.28 fibrin...
Camellia is a well-known ornamental flower native to Southeast of Asia, including regions such as Japan, Korea and South China. However, most species in the genus are cold sensitive. To elucidate stress responses camellia plants, we carried out deep transcriptome sequencing 'Jiangxue', cold-tolerant cultivar japonica, approximately 1,006 million clean reads were generated using Illumina technology. The assembly produced 367,620 transcripts, 207,592 unigenes. Overall, 28,038 differentially...
A Gram-stain-negative, short rod-shaped bacterium, designated 26DY36(T), was isolated from a deep-sea sediment sample collected the North Atlantic Rise. The isolate required NaCl and grew best with 2 % (w/v) sea salts at temperature of 30-35 °C pH 7.0. It formed yellow colonies, produced carotenoid-like pigments did not produce bacteriochlorophyll a. Strain 26DY36(T) positive for hydrolysis aesculin, gelatin, tyrosine Tweens 20, 40, 60 80, but negative casein, DNA starch. major respiratory...
Three Gram-staining-negative, aerobic and rod-shaped strains, designated as T40-1T, T40-3T JL-62T, were isolated from the deep-sea water in southwest Indian ridge. For strain growth occurred at 15-37 °C (optimum, 28 °C), pH 6.0-9.0 7.5) presence of 0.5-5.0 % NaCl (w/v; optimum, 2.0 %). Strain could grow 15-40 with 0.5-11.0 %, w/v) 6.0-9.5 8.0). The temperature, salinity ranges for JL-62T 30 5.5-9.0 7.5-8.0) 0.5-9.0 4.0 Ubiquinone-10 was sole ubiquinone all major fatty acids (>20 %) summed...
Two new xanthones (1 and 2) were isolated from the deep-sea-derived fungus Penicillium sp. MCCC 3A00126 along with 34 known compounds (3-36). The structures of established by spectroscopic data. absolute configuration 1 was validated comparison experimental calculated ECD spectra. All evaluated for cytotoxicity ferroptosis inhibitory activities. Compounds 14 15 exerted potent against CCRF-CEM cells, IC50 values 5.5 3.5 μM, respectively, whereas 26, 28, 33, significantly inhibited...
A Gram-stain-negative, aerobic and rod-shaped bacterium, designated as HZG-20 T , was isolated from a tidal flat in Zhoushan, Zhejiang Province, China. The 16S rRNA sequence similarities between strain Pikeienuella piscinae RR4-56 Coraliihabitans acroporae NNCM2 Parvibaculum indicum P31 Zhengella mangrovi X9-2-2 were 98.9, 91.7, 91.0 91.0%, respectively. Colonies of 1.4 mm diameter, milky white, round, smooth convex after cultivating on marine agar at 30 °C for 48 h. Cells catalase...
Importance Hospital clinicians may request that security personnel search patients’ rooms and belongings in response to suspected possession or use of illicit substances. Although searches are intended protect patient employee safety, little is known about outcomes consequences for clinical care. Objective To investigate the context room among patients with substance-related hospital encounters. Design, Setting, Participants Retrospective cohort study incident reports electronic health...
The isolation and structure elucidation of two cyanobacterial debromoaplysiatoxin (DAT) analogues, neo-debromoaplysiatoxin A (1) B (2), were reported found to possess 6/10/6 6/6/6 fused-ring systems, respectively, which are rarely seen among aplysiatoxins. Both compounds exhibited potent blocking activity against Kv1.5 with IC50 values 6.94 ± 0.26 0.30 0.05 μM, respectively. These findings suggest the potential aplysiatoxin analogues in modulating ionic channels also provide links between...
Two Gram-stain-negative, aerobic, motile by a single polar flagellum and rod-shaped strains, designated SCS-49T SCS-111, were isolated from seawater of the South China Sea. The two strains grew at 4-35 °C, with 0.5-7.5 % (w/v) NaCl pH 6.5-9.0 able to reduce nitrate. Q-8 was sole ubiquinone. major fatty acids C16 : 0, C18 1ω7c summed feature 3 (C16 and/or 1ω6c). lipids included diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol, phospoglycolipid, three unidentified...
Bacterial secondary metabolites have huge application potential in multiple industries. Biosynthesis of bacterial are commonly encoded a set genes that organized the metabolism biosynthetic gene clusters (SMBGCs). The development genome sequencing technology facilitates mining SMBGCs. Marine Streptomyces is valuable resource metabolites. In this study, 87 marine genomes were obtained and carried out into comparative genomic analysis, which revealed their high genetic diversity due to...
Camellia is a genus of flowering plants in the family Theaceae, and several species this have economic importance. Although great deal molecular makers has been developed for assisted breeding past decade, number simple sequence repeats (SSRs) publicly available insufficient. In study, total 28,854 potential SSRs were identified with frequency 4.63 kb. A 172 primer pairs synthesized preliminarily screened 10 C. japonica accessions, these pairs, 111 found to be polymorphic. Fifty-one...
Chemical investigation of the deep-sea-derived fungus Rhizopus sp. W23 resulted in identification six new (1-3, 6, 8, 9) and 12 known (4, 5, 10-19) cyclocitrinol analogues, together with one handling artifact (7), all featuring an unusual 7/7/6/5-tetracyclic scaffold bicyclo[4.4.1] A/B rings. Norcyclocitrinoic acids A B (1, 2) represent second occurrence 24,25-bisnor cyclocitrinols. Structures were assigned to steroids on basis extensive spectroscopic analysis X-ray crystallography. Compound...
Scanning bio-sequence database and finding similarities among DNA protein sequences is basic important work in bioinformatics field. To solve this problem, Needleman-Wunschh (NW) algorithm a classical precise tool, Smith-Waterman (SW) more practical for its capability to find between subsequences. Such algorithms have computational complexity proportional the length product of both involved sequences, hence processing time becomes insufferable due exponential growth speed great amount...
An aerobic, brown-pigmented, non-spore-forming, endophytic bacterium, designated strain Zy-3(T), was isolated from root nodules of Sphaerophysa salsula, a native leguminous herb belonging to the family Leguminosae growing in north-western China. Cells Zy-3(T) were non-motile, Gram-negative rods. Strain produced siderophores and showed antifungal activity. Phylogenetic analysis 16S rRNA gene sequence indicated that closest relative this organism Paracoccus halophilus HN-182(T) (96.6 %...