A5100703913- Marine Sponges and Natural Products
- Microbial Natural Products and Biosynthesis
- Microbial Metabolism and Applications
- Fungal Biology and Applications
- Geological and Geochemical Analysis
- Coastal wetland ecosystem dynamics
- Coastal and Marine Dynamics
- Seaweed-derived Bioactive Compounds
- Microbial Community Ecology and Physiology
- Seismic Waves and Analysis
- Methane Hydrates and Related Phenomena
- Hydrocarbon exploration and reservoir analysis
- Bacterial biofilms and quorum sensing
- Geology and Paleoclimatology Research
- Oceanographic and Atmospheric Processes
- Geological and Geophysical Studies
- Hydrology and Sediment Transport Processes
- Natural product bioactivities and synthesis
- Oil Spill Detection and Mitigation
- Phytochemical Studies and Bioactivities
- earthquake and tectonic studies
- Antimicrobial Resistance in Staphylococcus
- Water Quality Monitoring Technologies
- Plant Pathogens and Fungal Diseases
- Geological formations and processes
Ministry of Natural Resources
2019-2024
Fujian Institute of Oceanography
2022-2024
Qingdao Institute of Marine Geology
2019-2024
Laoshan Laboratory
2024
Qingdao National Laboratory for Marine Science and Technology
2022-2024
China Geological Survey
2020-2022
Feed Research Institute
2013
Zhejiang Environmental Monitoring Center
2010
Chemical investigation of the deep-sea-derived fungus Rhizopus sp. W23 resulted in identification six new (1-3, 6, 8, 9) and 12 known (4, 5, 10-19) cyclocitrinol analogues, together with one handling artifact (7), all featuring an unusual 7/7/6/5-tetracyclic scaffold bicyclo[4.4.1] A/B rings. Norcyclocitrinoic acids A B (1, 2) represent second occurrence 24,25-bisnor cyclocitrinols. Structures were assigned to steroids on basis extensive spectroscopic analysis X-ray crystallography. Compound...
A systematic chemical investigation of the deep-sea-derived fungus Aspergillus versicolor 170217 resulted in isolation six new (1-6) and 45 known (7-51) compounds. The structures compounds were established on basis exhaustive analysis their spectroscopic data theoretical-statistical approaches including GIAO-NMR, TDDFT-ECD/ORD calculations, DP4+ probability analysis, biogenetic consideration. Citriquinolinones (1) B (2) feature a unique isoquinolinone-embedded citrinin scaffold, representing...
Three new polyketides (penidihydrocitrinins A–C, 1–3) and fourteen known compounds (4–17) were isolated from the deep-sea-derived Penicillium citrinum W17. Their structures elucidated by comprehensive analyses of 1D 2D NMR, HRESIMS, ECD calculations. Compounds 1–17 evaluated for their anti-inflammatory anti-osteoporotic bioactivities. All isolates exhibited significant inhibitory effects on LPS-stimulated nitric oxide production in murine brain microglial BV-2 cells a dose-response manner....
Three new polyketides (penidihydrocitrinins A–C, 1–3) and 14 known compounds (4–17) were isolated from the deep-sea-derived Penicillium citrinum W17. Their structures elucidated by comprehensive analyses of 1D 2D NMR, HRESIMS, ECD calculations. Compounds 1–17 evaluated for their anti-inflammatory anti-osteoporotic bioactivities. All isolates exhibited significant inhibitory effects on microglial activation in LPS-stimulated BV-2 cells a dose-response manner. Notably, compound displayed...
A systematic investigation combined with a Global Natural Products Social (GNPS) molecular networking approach, was conducted on the metabolites of deep-sea-derived fungus Samsoniella hepiali W7, leading to isolation three new fusaric acid derivatives, hepialiamides A-C (1-3) and one novel hybrid polyketide hepialide (4), together 18 known miscellaneous compounds (5-22). The structures were elucidated through detailed spectroscopic analysis. as well TD-DFT-based ECD calculation. All isolates...
The Cladosporium fungi, one of the largest genera dematiaceous hyphomycetes, could produce various bioactive secondary metabolites. From AcOEt-soluble extract oxysporum 170103, three new secopatulolides (1-3) and thirteen known compounds (4-16) were obtained. Their structures established by detailed analysis NMR HR-ESI-MS data. All sixteen tested for antibacterial activity against Vibrio parahemolyticus, ergosterol (10) presented moderate effect with minimum inhibitory concentration (MIC) 32...
In recent years, development activities have had a significant impact on the environment of Jiaozhou Bay, China. To ensure sustainable economic and social Bay area, it is necessary to strengthen corresponding control measures. The important prerequisite properly understand environmental conditions laws natural change, especially dynamic processes sediment characteristics landform evolution. Based data continuous observation at 6 stations in for 25 hours, Hydrodynamic Eutrophication Model...
Carotenoids represent one of the most widely distributing and structurally diverse classes natural pigments. Over 600 different carotenoids have been found in nature some them are used foods,feeds,pharmaceuticals cosmetics. Some microorganisms ability to synthesize with complex structures. The microorganism could be produce carotenoids. One strain OB-2 which generates an orange pigment was isolated from water samples East Lake,Wuhan,where algae blooms were serious. By visible light spectrum...