A5100360600- Advanced Photocatalysis Techniques
- Nanoplatforms for cancer theranostics
- Advancements in Battery Materials
- Nanoparticle-Based Drug Delivery
- Supercapacitor Materials and Fabrication
- Covalent Organic Framework Applications
- Porphyrin and Phthalocyanine Chemistry
- RNA Interference and Gene Delivery
- Advanced Battery Materials and Technologies
- Electrocatalysts for Energy Conversion
- Advanced battery technologies research
- Luminescence and Fluorescent Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- biodegradable polymer synthesis and properties
- Advanced biosensing and bioanalysis techniques
- Photodynamic Therapy Research Studies
- Electrospun Nanofibers in Biomedical Applications
- Bioinformatics and Genomic Networks
- Graphene research and applications
- Electrochemical Analysis and Applications
- Graphene and Nanomaterials Applications
- Fuel Cells and Related Materials
- TiO2 Photocatalysis and Solar Cells
- Analytical Chemistry and Sensors
Northwest University
2022-2025
First Affiliated Hospital of Chengdu Medical College
2024-2025
Xiamen University of Technology
2022-2025
Changchun University of Science and Technology
2016-2025
Shandong Academy of Sciences
2024-2025
Qilu University of Technology
2024-2025
National Health and Family Planning Commission
2022-2025
Peking University
2015-2025
Tangshan People's Hospital
2024
Qingdao University
2013-2024
Exploring efficient and earth-abundant electrocatalysts for water splitting is crucial various renewable energy technologies. In this work, iron (Fe)-doped nickel phosphide (Ni2P) nanosheet arrays supported on foam (Ni1.85Fe0.15P NSAs/NF) are fabricated through a facile hydrothermal method, followed by phosphorization. The electrochemical analysis demonstrates that the Ni1.85Fe0.15P NSAs/NF electrode possesses high electrocatalytic activity splitting. 1.0 M KOH, only needs overpotentials of...
Abstract Triple negative breast cancer (TNBCs), known as an immunologically cold tumor, is difficult to completely eliminate with existing monotherapies, let alone metastasis and recurrence. It urgent design a rational combination of multiple therapies programmatically reconstitute tumor microenvironment (TME) reverse the immune “cold” into “hot” inflammatory tumors improve therapeutic effect. Hence, in this work, multifunctional nanosystem (FeSH NPs) that integrates metal‐polyphenol...
Abstract The chemotherapy of glioblastoma is severely hindered by the immunosuppressive tumor microenvironment, especially growth factor β (TGF‐β), an cytokine. In this study, it proposed to employ RNAi‐based immunomodulation modify immune microenvironment and improve effect chemotherapy. Herein, a nanotheranostic system (Angiopep LipoPCB(Temozolomide+BAP/siTGF‐β), ALBTA) with dual targeting ROS response established for intracranial treatment. traceable nanoparticles exhibit strong siRNA...
Due to the vast differences in chemical properties among small molecule drugs, nucleotide and superparamagnetic iron oxide nanocubes (SPIONs), such as charge hydrophobicity, entrapment of these within a single carrier for traceable synergistic therapy has been proven difficult. Herein, we synthesize positively charged polyprodrug amphiphiles. The hydrophobic unit amphiphiles is charged, which can simultaneously load SPIONs absorb negative let-7b antisense oligonucleotide construct...
This work develops the NiMnO3/NiMn2O4 ilmenite/spinel hybrid oxides as highly efficient bifunctional catalysts toward both oxygen evolution reaction (OER) and reduction (ORR). They are prepared with aid of pollen, using a two-step annealing method. The interaction between NiMnO3 NiMn2O4 nanoparticles results in an enhanced charge transfer active species electrolytes, which is favorable for their electrocatalytic activities. surface oxidation states Ni Mn can be tuned by greatly influences...
To explore a universal electrode material for the high-performance electrochemical storage of Li+, Na+, and K+ ions remains big challenge. Herein, we propose "trinity" strategy to coat SnO2 hollow nanospheres using dual carbon layer from polydopamine-derived nitrogen-doped graphene. Thereinto, structures with sufficient void space could buffer volume expansion, whereas carbon-confined not only elastically prevent aggregation nanoparticle ensure structural integrity but also immensely improve...
Abstract An in situ coupling strategy to prepare Co 9 S 8 /S and N dual-doped graphene composite (Co /NSG) has been proposed. The key point of this is the function-oriented design organic compounds. Herein, cobalt porphyrin derivatives with sulfo groups are employed as not only agents form anchor on situ, but also heteroatom-doped agent generate graphene. tight multiple active sites endows materials fast electrochemical kinetics excellent stability for both oxygen reduction reaction (ORR)...
Conjugated carbonyl compounds are deemed as high theoretical capacity and green electrode materials for lithium-ion batteries (LIBs) but limited by their dissolution poor electronic conductivity. In this paper, we have successfully synthesized a series of multicarbonyl conjugated polymers using the coupling polymerization reaction then constructed carbonyl-conjugated polymer/carbon nanotube hybrid films vacuum-filtration method. Importantly, could serve flexible, binder-free, free-standing...
Covalent organic polymers (COPs) provide an interesting platform for constructing the low-cost and highly efficient multifunctional electrocatalysts in view of their tailorable structures properties. Herein, Co-phthalocyanine-based COPs (CoPc-COPs) are constructed using cobalt tetraaminophthalocyanine (CoPc(NH2)4) as building unit phosphonitrilic chloride trimer (Cl6N3P3) linker group, which serve self-carrier enriched with Co, P, N, C to derive Co2P nanoparticles anchored on P codoped...
Abstract Immunotherapy has become a powerful cancer treatment, but only small fraction of patients have achieved durable benefits due to the immune escape mechanism. In this study, epigenetic regulation is combined with gene therapy-mediated checkpoint blockade relieve PPD (i.e., m P EG-b-PLG/ EI-RT3/ D NA) developed mediate plasmid-encoding shPD-L1 delivery by introducing multiple interactions electrostatic, hydrogen bonding, and hydrophobic interactions) polyproline II (PPII)-helix...
Circulating cell-free DNA (cfDNA) released by damaged cells causes inflammation and has been associated with the progression of sepsis. One proposed strategy to treat sepsis is scavenge this inflammatory circulating cfDNA. Here, we develop a cfDNA-scavenging nanoparticle (NP) that consists cationic polyethylenimine (PEI) different molecular weight grafted zeolitic imidazolate framework-8 (PEI-g-ZIF) in simple one-pot process. PEI-g-ZIF NPs fabricated using PEI 1800 25k but not 600 suppressed...
Abstract The problem of antimicrobial resistance (AMR) caused by the abuse antibiotics is becoming serious. development antibacterial materials with synergistic efficiency and treatment deep tissue/organ infections imminent. Herein, nanoparticles (MPH NPs) are prepared loading peptide polymyxin B (PMB) on Fe‐based MOF (MIL‐100) hyaluronic acid (HA) modification. MPH NPs exerts effects chemodynamic therapy (CDT) release PMB. have broad‐spectrum properties Gram‐negative bacteria ( E. coli ,...
Organic solvent nanofiltration has been commonly used in the pharmaceutical and petroleum chemistry industries. As a two-dimensional (2D) nanomaterial, graphene oxide (GO) nanosheets have great potential for fabrication of organic membranes, while unfavorable swelling peeling GO membrane hampered their practical application. Herein, hybrid membranes with strong stability were designed using reduced (rGO) nanoflake as intercalation poly(vinyl alcohol) (PVA) binder to improve interfacial...
Abstract Developing multifunctional photocatalysts with intelligent self‐adjusting is of great significance in the photocatalytic process. Herein, a smart covalent organic framework (Por‐HQ‐COF) phenol‐quinone conversion structure pH changes constructed for photooxidation, photoreduction, and H 2 O production. As photocatalyst, Por‐HQ‐COF can convert into Por‐BQ‐COF intelligently trigger including solution pH, vice versa. The reconstruction not only significantly alters morphologies specific...
Current high-throughput protein-protein interaction (PPI) data do not provide information about the condition(s) under which interactions occur. Thus, identification of condition-responsive PPI sub-networks is great importance for investigating how a living cell adapts to changing environments.In this article, we propose novel edge-based scoring and searching approach extract sub-network responsive conditions related some investigated gene expression profiles. Using approach, what...
Abstract Motivation: Differentially expressed gene (DEG) lists detected from different microarray studies for a same disease are often highly inconsistent. Even in technical replicate tests using identical samples, DEG detection still shows very low reproducibility. It is believed that current small will largely introduce false discoveries. Results: Based on statistical model, we show even it likely the selected be inconsistent presence of measurement variations. Therefore, apparently...