A5001473058- Cancer Cells and Metastasis
- Galectins and Cancer Biology
- Adipokines, Inflammation, and Metabolic Diseases
- Protein Tyrosine Phosphatases
- Renewable energy and sustainable power systems
- Healthcare Systems and Public Health
- Balkan and Eastern European Studies
- Cancer Genomics and Diagnostics
- Immune Cell Function and Interaction
- Signaling Pathways in Disease
- IL-33, ST2, and ILC Pathways
- Graphene and Nanomaterials Applications
- Chemotherapy-induced organ toxicity mitigation
- Medicinal plant effects and applications
- Diet and metabolism studies
- Silicon Carbide Semiconductor Technologies
- Pneumonia and Respiratory Infections
- Dental Research and COVID-19
- Pediatric Urology and Nephrology Studies
- Global Energy Security and Policy
- Fire Detection and Safety Systems
- Military, Security, and Education Studies
- Power Quality and Harmonics
- Urological Disorders and Treatments
- Aluminum toxicity and tolerance in plants and animals
University of Kragujevac
2015-2025
Clinical Centre of Kragujevac
2024
University of Mostar
2014-2023
In this study we have produced silver nanoparticles (AgNPs) using Serbian traditional tea Bosiljak (Ocimum basilicum L.) extract in a single step without the involvement of toxic chemicals. The method employed is environmentally friendly, simple, and cost-effective, involving use an aqueous plant that serves as both reducing stabilizing agent for AgNPs. AgNPs were studied UV–Vis spectroscopy, field emission scanning electron microscopy (FESEM), transmission (TEM), dynamic light spectroscopy...
Background:Trapa natans L. fruits and leaf extracts have a broad range of immunomodulatory, anti-inflammatory, antioxidant effects; however, their effects on cardiac protection not been investigated. Objective: The study aims to test the biological activity Trapa extract (TNE) in cisplatin (CDDP)-induced cardiotoxicity. Methods: Wistar albino rats received single dose CDDP intraperitoneally TNE ones per day for 2 weeks orally. Cardiac inflammation, necrosis, fibrosis were determined by...
Type 1 diabetes is an autoimmune disease caused by the immune-mediated destruction of pancreatic β-cells. Prevention type requires early intervention in process against beta-cells islets Langerhans, which believed to result from disordered immunoregulation. CD4+Foxp3+ regulatory T cells (Tregs) participate as one most important cell types limiting process. The aim this study was investigate effect exogenous IL-33 multiple low dose streptozotocin (MLD-STZ) induced and delineate its role...
Aims/hypothesis: Galectin 3 appears to have proinflammatory role in several inflammatory and autoimmune diseases. Also, there is evidence that galectin plays a both, type 1 2 diabetes. During obesity hematopoetic cells-derived induces insulin resistence. While the of expressed islet invading immune cells both diabetes has been studied, importance expression this molecule on target pancreatic beta not defined. Methods: To clarify during obesity-induced diabetogenesis, we developed transgenic...
Nowadays, biomedicine is a multidisciplinary science that requires very broad approach to the study and analysis of various phenomena essential for better understanding human health. This deals with use numerical simulations understand processes cancer viability apoptosis in treatment commercial chemotherapeutics. Starting from many experiments examining cell real-time, determining type death genetic factors control these processes, lot results were obtained. These vitro test used create...
Adiponectin is one of the most important molecules in body's compensatory response to development insulin resistance. By trying maintain sensitivity, increase secretion and prevent inflammation, adiponectin tries glucose homeostasis. Interleukin-33, which belongs group alarmins, also promotes secretion. Interleukin-33 might be either pro-inflammatory or anti-inflammatory depending on disease model. However, interleukin-33 has shown various protective effects CVD, obesity diabetes. The aim...
Galectin-3 (Gal-3) has diverse roles in inflammatory and autoimmune diseases. There is evidence that Gal-3 plays a role both type 1 2 diabetes. While the of expression immune cells invading pancreatic islets experimental model diabetes mellitus been already studied, importance overexpression target β not defined. Therefore, we used multiple low doses streptozotocin (MLD-STZ)-induced C57Bl/6 mice to analyze effect transgenic (TG) cells. Our results demonstrated protected from apoptosis...
Dual antiplatelet therapy is recommended after acute coronary syndrome or percutaneous intervention with stent implantation. Many of the patients on dual receive β-blockers; some them could have antiaggregatory effect. Bisoprolol a highly selective adrenoceptor-blocker, which often used in settings therapy. Its antiaggregative effect has not been extensively studied. Therefore, aim this study to investigate bisoprolol ADP-induced platelet aggregation therapy.Platelet aggregability measured...
(1) Background: Cancer stem cells (CSCs) are a subpopulation of in tumor that can self-regenerate and produce different types with the ability to initiate growth dissemination. Chemotherapy resistance, caused by numerous mechanisms which tissue manages overcome effects drugs, remains main problem cancer treatment. The identification markers on cell surface specific CSCs is important for understanding this phenomenon. (2) Methods: expression CD24, CD44, ALDH1, ABCG2 was analyzed two lines,...
This cross-sectional study aimed to assess the correlation between subjective oral health status and mental in a group of university students Serbia. The included 948 students, aged 18 27, from Faculty Medical Sciences, University Kragujevac, Serbia, was conducted 2020. World Health Organization's Oral Questionnaire for Adults utilized evaluate respondents' self-perceived hygiene practices. existence depressive symptoms evaluated using Beck Depression Inventory-II (BDI-II), Zung self-rating...
Background: Depression is one of the most common mental health diseases among people. Retirement, lost partner, multiple are some factors that contributes to depression elderly Older people tend have weaker oral hygiene and more dental prosthetics which also affect their mood, satisfaction self-esteem. The aim this research was determine correlation characteristics in adults older than 65 years Serbia. Methods Objectives: survey conducted as a part fourth National Population Health Survey...
Metabolic syndrome is a significant pro-inflammatory and pro-coagulant condition. The clinical association of adiponectin, mainly antidiabetogenic molecule, its interaction with platelets platelet indices remains insufficiently investigated. aim our study was to investigate the adiponectin in patients metabolic syndrome. investigation conducted as cross-sectional involving 113 subjects: 63 diagnosis syndrome, 50 healthy controls - clear inclusion exclusion criteria. group divided into two...
U članku je riječ o Mileni Preindslberger-Mrazović, prvoj bosansko-hercegovačkoj novinarki i vlasnici urednici lista Bosnische Post te književnici, čiji su tekstovi nadahnuti ljudima zemljom u kojoj provela četiri desetljeća svoga života. Budući da pisala isključivo na njemačkome jeziku, njezini dugo ostali nepoznati domaćoj, javnosti čitateljima. ovome prilogu obrađen dio njezinih članaka feljtona koje objavljivala različitim novinama časopisima, a ponajviše listu Post. tekstovima kojima do...
Introduction. The respiratory tract is the most common site of opportunistic infections in patients with acquired immunodeficiency syndrome, and failure leading cause death these cases. In addition, use mechanical ventilation treatment carries a high risk nosocomial pneumonia caused by multidrug-resistant strains bacteria. Case report. We present human virus-positive patient positive outcome Pneumocystis jiroveci whose condition progressed to acute distress syndrome development complications...
Abstract The use of medications that improve the physical performance an individual represents a very serious worldwide health problem. abuse these is increasing. Herein, we describe patient, at age 20, who was hospitalized due to loss consciousness and difficulty breathing. At admission, patient unconsciousness, tahi-dyspnoic, had pale complexion athletic build. In gas analyses, extremely low saturation observed, followed by acidosis, heavy hypoxia with normocapnia, higher lactates,...
Abstract Galectin 3 is a lectin expressed in many tissues with significant biological role physiological and pathological processes. Our review aims to sublimate the effects of galectin on β-cells function survival. Data about effect β- cells are scarce contradictory. Several studies have shown that reduced activity gene reduces risk developing type 1 diabetes an experimental model deficient mice. On other side, mice selectively enhanced expression β-cells, was increased this has protective...