- Carbon Nanotubes in Composites
- Graphene research and applications
- Advanced biosensing and bioanalysis techniques
- Mechanical and Optical Resonators
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Neuroblastoma Research and Treatments
- Biosensors and Analytical Detection
- Sarcoma Diagnosis and Treatment
- MXene and MAX Phase Materials
- 2D Materials and Applications
- Nanopore and Nanochannel Transport Studies
- Nanowire Synthesis and Applications
- Nanotechnology research and applications
- Mosquito-borne diseases and control
- Graphene and Nanomaterials Applications
- Near-Field Optical Microscopy
- Neutropenia and Cancer Infections
- Boron and Carbon Nanomaterials Research
- Cancer therapeutics and mechanisms
- Virus-based gene therapy research
- RNA Interference and Gene Delivery
- Gene Regulatory Network Analysis
- Acute Lymphoblastic Leukemia research
- Neuroendocrine Tumor Research Advances
Boston University
2011-2024
Arizona State University
2016-2024
Tempe Union High School District
2017-2021
Harvard University
2011-2017
Northwestern University
2006-2013
Harvard University Press
2011-2013
University of Pisa
2009
Ludwig-Maximilians-Universität München
2008-2009
University of Oklahoma
2009
Rice University
2009
We conducted a randomized controlled trial to determine whether intensive multi-agent adjuvant chemotherapy improves the chances of relapse-free survival in patients with nonmetastatic high-grade osteosarcoma extremity, as compared concurrent controls. After undergoing definitive surgery, 36 were randomly assigned or observation without treatment. At two years actuarial was 17 percent control group, similar that found In studies before 1970, and 66 adjuvant-chemotherapy group (P<0.001)....
Graphene flakes with controlled thicknesses are isolated in solution using density gradient ultracentrifugation. These stable graphene dispersions produced the bile salt sodium cholate, which promotes graphite exfoliation and results graphene−surfactant complexes having buoyant densities that vary thickness. The sorted characterized atomic force microscopy Raman spectroscopy. differentiation offer superior performance transparent conductors than those conventional sedimentation-based...
Thin film transistors (TFTs) are now poised to revolutionize the display, sensor, and flexible electronics markets. However, there is a limited choice of channel materials compatible with low-temperature processing. This has inhibited fabrication high electrical performance TFTs. Single-walled carbon nanotubes (CNTs) have very mobilities can be solution-processed, making thin CNT-based TFTs natural direction for exploration. The two main challenges facing CNT-TFTs difficulty placing aligning...
Printing electronic components on plastic foils with functional liquid inks is an attractive approach for achieving flexible and low-cost circuitry applications such as bendable displays large-area sensors. The challenges printed electronics, however, include characteristically slow switching frequencies associated high supply voltages, which together impede widespread application. Combining printable high-capacitance dielectrics high-mobility semiconductors could potentially solve these...
Single-walled carbon nanotubes (SWNTs) are promising materials for transparent conduction as a result of their exceptional electrical, optical, mechanical, and chemical properties. However, since current synthetic methods yield polydisperse mixtures SWNTs, the performance SWNT conductive films has previously been hindered by semiconducting species. Here, we describe conductors produced using predominantly metallic SWNTs. Compared with unsorted material, enriched in SWNTs can enhance...
Atomically thin transition-metal dichalcogenides (TMDs) have attracted considerable interest because of their unique combination properties, including photoluminescence, high lubricity, flexibility, and catalytic activity. These properties suggest future uses for TMDs in medical applications such as orthodontics, endoscopy, optogenetics. However, few studies thus far investigated the biocompatibility mechanically exfoliated chemical vapor deposition (CVD)-grown pristine two-dimensional TMDs....
With the recent burst of activity surrounding solution-phase production graphene, comparatively little progress has been made toward generation graphene dispersions with tailored thickness, lateral area, and shape. The polydispersity dispersions, however, can lead to unpredictable or nonideal behavior once they are incorporated into devices since properties vary as a function its structural parameters. In this brief perspective, we overview problem polydispersity, methods under development...
Excitement surrounding the attractive physical and chemical characteristics of single walled carbon nanotubes (SWCNTs) has been tempered by concerns regarding their potential health risks. Here we consider lung toxicity nanoscale dispersed SWCNTs (mean diameter ∼1 nm). Because dispersion increases aspect ratio relative to as-produced aggregates, directly test prevailing hypothesis that associated with compared other structures is attributable large individual particles. Thirty days after...
We describe how iterative, orthogonal density gradient ultracentrifugation (DGU) separations can be used to produce nearly single-chirality (6,5) SWNTs. SWNT network transistors made from these highly pure, ≥98% semiconducting SWNTs simultaneously exhibit high on/off ratios, mobilities, and on-state conductances, suggesting their future application in integrated circuits near-infrared optoelectronic light emitters photodetectors.
This paper presents the high frequency performance of single-walled carbon nanotube (SWNT) field-effect transistors, with channel consisting dense networks purity semiconducting SWNTs. Using SWNT samples containing 99% pure SWNTs, we achieved operating frequencies above 80 GHz. record does not require aligned thus demonstrating remarkable potential random sorted SWNTs for electronics.
The ability to disperse pristine graphene at high concentrations in aqueous solutions is an enabling step for large-scale processing and emerging biomedical applications. Herein we demonstrate that nonionic, biocompatible block copolymers are able produce dispersions with exceeding 0.07 mg mL–1 via sonication centrifugation, resulting optical densities above 4 OD cm–1 the visible near-infrared regions of electromagnetic spectrum. dispersion efficiency using Pluronic Tetronic varies...
Current methods of synthesizing single-walled carbon nanotubes (SWNTs) result in racemic mixtures that have impeded the study left- and right-handed SWNTs. Here we present a method isolating different SWNT enantiomers using density gradient ultracentrifugation. Enantiomer separation is enabled by chiral surfactant sodium cholate, which discriminates between SWNTs thus induces subtle differences their buoyant densities. This sorting strategy can be employed for simultaneous enrichment...
Abstract Noroviruses are a primary cause of gastroenteritis and foodborne illness with cases that affect millions people worldwide each year. Inexpensive tests for norovirus do not require sophisticated laboratory equipment important tools ensuring patients receive timely treatment containing outbreaks. Herein, we demonstrate low-cost colorimetric assay detects from clinical samples by combining paper-based cell-free transcription–translation systems, isothermal amplification virus...
Two-dimensional semiconducting transition metal dichalcogenides (TMDCs) like molybdenum disulfide (MoS2) are generating significant excitement due to their unique electronic, chemical, and optical properties. Covalent chemical functionalization represents a critical tool for tuning the properties of TMDCs use in many applications. However, inertness has thus far hindered robust these materials. Previous reports have required harsh treatments or converting into metallic phases prior covalent...
We report the radio-frequency performance of carbon nanotube array transistors that have been realized through aligned assembly highly separated, semiconducting nanotubes on a fully scalable device platform. At gate length 100 nm, we observe output current saturation and obtain as-measured, extrinsic gain power cut-off frequencies, respectively, 7 GHz 15 GHz. While is comparable to state-of-the-art improved. The de-embedded, intrinsic frequencies 153 30 are highest values experimentally...
Abstract Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors with the potential provide decentralized and low-cost molecular diagnostics. However, it remains a challenge deliver this sensing capacity into hands of users practical manner. Here, we leverage glucose meter, one most widely available point-of-care devices, serve as universal reader for these We describe translator that can convert activation conventional output be read by off-the-shelf...