A5026321612- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Nosocomial Infections in ICU
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Cardiac and Coronary Surgery Techniques
- Neonatal Respiratory Health Research
- Anesthesia and Neurotoxicity Research
- Mechanical Circulatory Support Devices
- Hydrogen's biological and therapeutic effects
Tomsk National Research Medical Center
2023-2025
Russian Academy of Sciences
2023-2025
The aim of the study was to evaluate antimicrobial effect single and repeated nitric oxide (NO) exposure on major pathogens nosocomial pneumonia isolated from sputum cardiac surgery patients. Materials Methods. A 24-hour culture microorganisms pan-resistant isolates Pseudomonas aeruginosa , Escherichia coli Acinetobacter baumannii Klebsiella pneumoniae inpatient patients with pneumonia, as well strains P. E. American Type Culture Collection (ATCC), were exposed 200 ppm NO (experimental...
Nosocomial pneumonia is the most common infectious complication following cardiac surgical procedures. The aim was to assess efficacy and safety of repeated inhalation sessions 200 ppm nitric oxide for nosocomial Methods. pilot single-center prospective randomized study included spontaneously breathing patients with cardiovascular diseases, operated on under artificial circulation, a complicated postoperative period in form pneumonia. These ( n = 40) underwent procedures cardiopulmonary...
Objective This study aimed to assess the safety and potential efficacy of high-dose inhaled nitric oxide therapy for prevention postoperative pneumonia in cardiac surgery patients
The article describes a clinical case of inhalation therapy with high doses nitric oxide (NO) in comorbid patient severe course COVID-19. An air stream containing NO was generated using the PLAZON device. High-dose administered as life-saving option due to lack effect from treatment delivered accordance current national guidelines for safety and efficacy technique demonstrated.
Introduction: Organoprotective effects of perioperative nitric oxide delivery towards the heart and kidneys have been demonstrated many times in cardiac surgery but information about its ability to prevent respiratory complications is extremely limited. Objective: This study aimed at evaluation efficacy safety for preventing during surgeries involving cardiopulmonary bypass patients with an increased risk adverse events identification factors postoperative acute respiratory. Methods: A...
Aim . To study the prevalence and risk factors (RF) for hospital-acquired pneumonia (HAP) after on-pump cardiac surgery in a modern cohort of patients. Material methods This retrospective analysis medical records cardiovascular patients, operated on period from January 1, 2022 to December 31, 2022. The consistently included 417 patients who underwent surgery. incidence timing HAP development were assessed. influence main demographic, clinical, perioperative was studied. Results per year...
Highlights For the first time, incidence and timing of development postoperative pneumonia in patients undergoing surgical reconstruction aortic arch post-covid period were studied. Risk factors for predictors severe course disease this cohort identified. The results obtained will make it possible to differentiate at risk developing from general population targeted perioperative prevention complication. Abstract Aim. To study nosocomial (NP) after surgery, determine impact on its severity...