A5024140093- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Polyomavirus and related diseases
- Chronic Lymphocytic Leukemia Research
- Sarcoma Diagnosis and Treatment
- Nail Diseases and Treatments
- Education, Psychology, and Social Research
- Eosinophilic Disorders and Syndromes
- Cutaneous lymphoproliferative disorders research
- Hair Growth and Disorders
- Cell Image Analysis Techniques
- Media, Gender, and Advertising
- HIV/AIDS oral health manifestations
- Fungal Infections and Studies
- DNA Repair Mechanisms
- Oral and gingival health research
- Colorectal and Anal Carcinomas
- Oral Health Pathology and Treatment
- Neurofibromatosis and Schwannoma Cases
- Skin Protection and Aging
- Lymphoma Diagnosis and Treatment
- Neonatal skin health care
- Advertising and Communication Studies
Charles University
2012-2024
Pilsen Tools (Czechia)
2016
University Hospital Brno
2012
Universidad Nacional de La Plata
2006
Abstract Background The proportion of Merkel cell carcinomas (MCCs) in solid‐organ transplant recipients (SOTR) harbouring polyomavirus (MCPyV) is unknown, as are factors affecting their outcomes. Objective To describe clinicopathological features MCC SOTR, investigate the tumoral MCPyV‐status and identify associated with tumour Methods Retrospective, international, cohort‐study. was investigated by immunohistochemistry polymerase chain reaction. Results A total 30 SOTR 44 consecutive...
Introduction Solid organ transplant recipients (SOTRs) are believed to have an increased risk of metastatic cutaneous squamous-cell carcinoma (cSCC), but reliable data lacking regarding the precise incidence and associated factors. Methods In a prospective cohort study, including 19 specialist dermatology outpatient clinics in 15 countries, patient tumor characteristics were collected using standardized questionnaires when SOTRs presented with new cSCC. After minimum 2 years follow-up,...
Abstract: Close relationship between melanocytes and neural cells is accepted to reflect their common derivation from the crest tumors combining both elements. We present a series of 10 patients with giant congenital melanocytic nevi (CMN) in which secondary proliferation (11 lesions) schwannian and/or perineuriomatous differentiation developed course disease. The age (4 male 6 female) at time surgery histological assessment varied 3 months 57 years. Histopathologically, following subgroups...
Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor used in treatment of advanced NSCLC.Patients harboring EGFR or KRAS mutations represent minority all patients caucasian population and there no available predictor for a predominant group the wild-type genes.Skin rash most frequent manifestation cutaneous toxicity erlotinib.Rash associated with good therapeutic response.We aimed at evaluation as effect erlotinib genes to assess its possible usage clinical...
Muir-Torre syndrome (MTS), a phenotypic variant of the more common hereditary nonpolyposis colorectal cancer syndrome, or Lynch is an autosomal dominantly inherited condition that combines at least one cutaneous sebaceous neoplasm and visceral malignancy. Most patients (~90%) with MTS carry mutations in MSH2 gene; less than 10% cases are associated mutation MLH1 gene, only 3 pathogenic MSH6 have been previously documented. We report family affected which members (father 2 sons) were found to...
Organ transplant recipients (OTR) are at high risk for cutaneous squamous cell carcinomas (SCC). We aimed to define clinically meaningful patient-reported warning signals predicting the presence of invasive SCC. Patient-reported signs and symptoms 812 consecutively biopsied skin lesions from 410 OTR were determined by questionnaire physical examination related subsequent biopsy-proven diagnoses. Receiver-operating characteristic (ROC) curve analyses used as a measure distinction between...
Organ transplant recipients (OTRs) have a highly increased risk of cutaneous squamous cell carcinomas (SCCs). Sensation pain in tumours is powerful patient‐reported warning signal for invasive SCCs OTRs. To investigate the impact painful vs. painless skin lesions and SCC other on overall mortality We followed 410 OTRs from 10 different centres across Europe North America between 2008 2015. These patients had been enrolled an earlier study to define clinically meaningful signals predicting...
Bimatoprost is a synthetic prostaglandin structural analogue used among other indications to increase eyelash growth. The aim of this prospective, open-label study was evaluate the safety and efficacy topical bimatoprost in treatment loss alopecia areata totalis (AT) universalis (AU). Study subjects applied ophthalmic (0.3 mg/ml) solution eyelid margins once nightly for at least 12 weeks (mean period 30.6 weeks). A total 16 out 17 completed study. Only with eyelashes present baseline...
Melanoma is the most aggressive skin cancer with ability to recur also after early-stage tumor surgery. The aim was identify melanoma patients at high risk of recurrence using liquid biopsy, estimating mutated BRAF ctDNA and level marker S100B in plasma.
Linfoma no Hodgkin oral relacionado al sida (LNHORS): Actualización y presentación de un caso clínico RESUMEN Introducción: Los linfomas No-Hodgkin presentan características propias cuando se asocian a la infección por el Virus Inmunodeficiencia Humana.La cavidad bucal es una las localizaciones tener en cuenta pacientes con Sida (LNHORS) Si bien registran casos los primeros estadios infección, diagnóstico previo diferencial estomatológico su seguimiento realizan nuestro medio frecuencia que...