A5075894092- High Altitude and Hypoxia
- Travel-related health issues
- Hepatitis C virus research
- Genetic and phenotypic traits in livestock
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Brucella: diagnosis, epidemiology, treatment
- Neurological and metabolic disorders
- Rangeland Management and Livestock Ecology
- Prion Diseases and Protein Misfolding
- Burkholderia infections and melioidosis
- Climate Change and Health Impacts
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Folate and B Vitamins Research
- Cancer, Hypoxia, and Metabolism
- Alcoholism and Thiamine Deficiency
- Genetic diversity and population structure
Memorial Hospital
2024
Sher-i-Kashmir Institute of Medical Sciences
2018-2019
The utility of cell-free (cf) DNA has extended as a surrogate or clinical biomarker for various diseases. However, more profound and expanded understanding the diverse cfDNA population its correlation with physiological phenotypes environmental factors is imperative using full potential. high-altitude (HA; altitude > 2,500 m above sea level) environment characterized by hypobaric hypoxia offers an observational case-control design to study differential profile in patients pulmonary edema...
A 45-year-old female without any past or family history of psychiatric illness presented to the emergency department with complaints abnormal behavior, irrelevant talking, restlessness, episodic crying, and decreased sleep 2-day duration. On detailed interview, attendants gave a an intermittent headache 6-month duration hearing impairment 4-month investigation, her cerebrospinal fluid was reactive, brucella titers were positive. She received appropriate treatment for 6 months short course...
Abstract The dramatic changes in physiology at high altitude (HA) as a result of the characteristic hypobaric hypoxia condition can modify innate and adaptive defense mechanisms body. As consequence, few sojourners visiting HA with mild or asymptomatic infection may have an enhanced susceptibility to high-altitude pulmonary edema (HAPE), acute but severe sickness. It develops upon rapid ascent altitudes above 2500 m, otherwise healthy individuals. Though HAPE has been studied extensively,...
Abstract Trans-Himalayan Ladakh has witnessed complex cultural movements and demographic changes since the Neolithic period, which is still continue despite harsh, inhospitable cold climate. Although geographically isolated from mainland South Asia, historic trade routes well connected accessible to travelers Tibet Central Asia. Despite its rich heritage, a detailed description of genetic landscape region completely lacking, particularly with regard genome-wide analysis larger sample sizes....
Abstract The effect of high altitude (HA, >2500 m) can trigger a maladaptive response in unacclimatized individuals, leading to various HA illnesses such as pulmonary edema (HAPE). present study investigates circulating cell free (cf) DNA, minimally invasive biomarker that elicit pro-inflammatory response. Our earlier observed altered cfDNA fragment patterns HAPE patients and the significant correlation these with peripheral oxygen saturation levels. However, unclear release...
Background: Gastrointestinal manifestations of thiamine deficiency have not been well described in literature. Authors aimed to study the symptoms gastrointestinal beriberi a cohort patients non-alcoholic Wernicke’s encephalopathy and review relevant literature.Methods: In retrospective analysis, case records 52 diagnosed with were analyzed for nature symptoms, their duration, severity associated findings, investigations response treatment. The available literature on disorders was...